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Araç Laboratory | The University of Chicago

Skip to main navigation. Skip to main content. The University of Chicago. Our laboratory uses molecular approaches to understand brain and neuron function. We are interested in neurons, synapse formation and validation, and specifically a protein family that is heavily expressed in the brain: Adhesion GPCRs. All Adhesion GPCRs contain an extracellular GAIN domain. Structural Biology of Adhesion GPCRs. Structural Biology has been and will be crucial for an understanding of Adhesion GPCR function. Of adhes...

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Araç Laboratory | The University of Chicago | arac.uchicago.edu Reviews
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Skip to main navigation. Skip to main content. The University of Chicago. Our laboratory uses molecular approaches to understand brain and neuron function. We are interested in neurons, synapse formation and validation, and specifically a protein family that is heavily expressed in the brain: Adhesion GPCRs. All Adhesion GPCRs contain an extracellular GAIN domain. Structural Biology of Adhesion GPCRs. Structural Biology has been and will be crucial for an understanding of Adhesion GPCR function. Of adhes...
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Araç Laboratory | The University of Chicago | arac.uchicago.edu Reviews

https://arac.uchicago.edu

Skip to main navigation. Skip to main content. The University of Chicago. Our laboratory uses molecular approaches to understand brain and neuron function. We are interested in neurons, synapse formation and validation, and specifically a protein family that is heavily expressed in the brain: Adhesion GPCRs. All Adhesion GPCRs contain an extracellular GAIN domain. Structural Biology of Adhesion GPCRs. Structural Biology has been and will be crucial for an understanding of Adhesion GPCR function. Of adhes...

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Katie and Katherine join our lab! | Araç Laboratory | The University of Chicago

http://arac.uchicago.edu/news/yue-lu-joins-our-lab-0

Skip to main navigation. Skip to main content. The University of Chicago. Katie and Katherine join our lab! Published on Aug 3, 2013. Welcome Katie and Katherine! We are excited to have two new and really excellent students rotate in our lab in Spring Quarter. Gabe Salzman has decided to join the lab as our first graduate trainee! We also had a great time with Chris Katanski, who joined us for a rotation in Winter Quarter. Our paper was published in Neuron! Demet got an R01! Celia Fernandez joined our lab.

2

Chen and Katarzyna join the lab! | Araç Laboratory | The University of Chicago

http://arac.uchicago.edu/news/chen-and-katarzyna-join-lab

Skip to main navigation. Skip to main content. The University of Chicago. Chen and Katarzyna join the lab! Published on Jul 18, 2014. We are excited to have two new students with us this summer: Chen Ding and Katarzyna Merdas! Chen is currently an undergraduate student from Peking University, China, and Katarzyna is an exchange Masters student from Wroclaw University of Technology, Poland. Welcome Chen and Katarzyna! Joins the lab as a graduate student! Our paper was published in Neuron! Demet got an R01!

3

Our paper came out in Structure! | Araç Laboratory | The University of Chicago

http://arac.uchicago.edu/news/our-paper-came-out-structure

Skip to main navigation. Skip to main content. The University of Chicago. Our paper came out in Structure! Published on Oct 8, 2015. Congratulations on the publication of our paper "Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion"! Our paper was published in Neuron! Demet got an R01! New undergraduate student joined our lab. Celia got CBC Postdoctoral Research Grant! Celia Fernandez joined our lab. The University of Chicago. 2017 The University of Chicago.

4

News | Araç Laboratory | The University of Chicago

http://arac.uchicago.edu/page/news

Skip to main navigation. Skip to main content. The University of Chicago. Latest News and Announcements. Our paper was published in Neuron! Congratulations on the publication of our paper "Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains"! Our paper was also mentioned in a press release. From UChicago Science Life. Read the full post. Demet got an R01! Congratulations to Demet on her R01! Read the full post. New undergraduate student joined our lab. Recei...

5

Our paper was published in Neuron! | Araç Laboratory | The University of Chicago

http://arac.uchicago.edu/news/our-paper-was-published-neuron

Skip to main navigation. Skip to main content. The University of Chicago. Our paper was published in Neuron! Published on Sep 28, 2016. Congratulations on the publication of our paper "Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains"! Our paper was also mentioned in a press release. From UChicago Science Life. Our paper was published in Neuron! Demet got an R01! New undergraduate student joined our lab. Celia got CBC Postdoctoral Research Grant!

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Get Help ▼. For Depositors ▼. X-Ray Diffraction data from VHH-L66 in Complex with Prefusion RSV F, source of 5TOK structure. Data DOI: 10.15785/SBGRID/427. Publication DOI: 10.1038/ncomms14158. Published: March 3, 2017. Data DOI: 10.15785/SBGRID/427. Publication DOI: 10.1038/ncomms14158. X-Ray Diffraction data from Single-Domain Antibody F-VHH-4, source of 5TP3 structure. Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4. Data DOI: 10.15785/SBGRID/426. Published: March 3, 2017.

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SBGrid In Your Lab. University of Maryland College Park. University of California, Davis. Washington University in St. Louis. Yale University School of Medicine. Dana Farber Cancer Institute. National Institutes of Health. Duke University School of Medicine. Johns Hopkins University School of Medicine. Berkeley Center for Structural Biology. Lawrence Berkeley National Laboratory. California Institute of Technology. Yale University School of Medicine. Institut de Biologie Structurale, Grenoble. Washington...

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Get Help ▼. For Depositors ▼. X-Ray Diffraction data from VHH-L66 in Complex with Prefusion RSV F, source of 5TOK structure. Data DOI: 10.15785/SBGRID/427. Publication DOI: 10.1038/ncomms14158. Published: March 3, 2017. Data DOI: 10.15785/SBGRID/427. Publication DOI: 10.1038/ncomms14158. X-Ray Diffraction data from Single-Domain Antibody F-VHH-4, source of 5TP3 structure. Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4. Data DOI: 10.15785/SBGRID/426. Published: March 3, 2017.

bmb.uchospitals.edu bmb.uchospitals.edu

Department of Biochemistry & Molecular Biology

http://bmb.uchospitals.edu/faculty/demet-arac-ozkan

Department of Biochemistry and Molecular Biology. Biochemistry and Molecular Biophysics. 929 E 57th St. GCIS. 929 E 57th St. Postdoctoral fellow, Stanford University. PhD in Molecular Biophysics, University of Texas Southwestern Medical Center at Dallas. BSc in Molecular Biology and Genetics, Bilkent University. Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion. Sep, 1 2015. Matching structure with function: the GAIN domain of adhesion-GPCR and PKD1-like proteins. Mar, 21 2012.

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