Jean Gariépy Research Laboratory - Department of Medical Biophysics, University of Toronto and the Ontario Cancer Institute.
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2075 Bayvi●●●●●●●●●●oom M7-434
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Jean Gariepy
2075 Bayvi●●●●●●●●●●oom M7-434
TO●●TO , Ontario, M5G2M9
Canada
View this contact
Jean Gariepy
2075 Bayvi●●●●●●●●●●oom M7-434
TO●●TO , Ontario, M5G2M9
Canada
View this contact
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Jean Gariépy Research Laboratory - Department of Medical Biophysics, University of Toronto and the Ontario Cancer Institute | jeangariepy.com Reviews
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Jean Gariépy Research Laboratory - Department of Medical Biophysics, University of Toronto and the Ontario Cancer Institute.
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Jean Gariépy Research Laboratory - Department of Medical Biophysics, University of Toronto and the Ontario Cancer Institute
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GE Healthcare MicroCal iTC200 System (Isothermal Titration Calorimetry. Direct and label-free measurement of binding affinity, stoichiometry, enthalpy, and entropy in one experiment. Lab applications: study of proteins, antibodies, peptides and aptamers. Biacore T200 - Surface Plasmon Resonance. Real time and label free measurement of biomolecular interactions providing high quality kinetic, affinity, concentration, specificity, selectivity, and thermodynamic interaction data. GE Healthcare ÄKTA Purifie.
Jean Gariépy Research Laboratory - Department of Medical Biophysics, University of Toronto and the Ontario Cancer Institute
http://www.jeangariepy.com/recentdev.html
A Rapid and Universal Tandem-Purification Strategy for Recombinant Proteins. The N-terminal HiCaM purification tag combines a (His)6 sequence for IMAC purification followed by a CaM module for HIC purification with phenyl sepharose. By virtue of the thrombin cleavage site (TCS), the target protein can either be cleaved on-column or eluted and subsequently cleaved with thrombin. 1) McCluskey AJ, Poon GMK, Gariépy J. (2007). A rapid and universal tandem-purification strategy for recombinant proteins.
Jean Gariépy Research Laboratory - Department of Medical Biophysics, University of Toronto and the Ontario Cancer Institute
http://www.jeangariepy.com/publications.html
Perform an automatic Pubmed search. To view all of Jean Gariépy's. Wu FT, Lee CR, Bogdanovic E, Prodeus A, Gariépy J, Kerbel RS. (2015) Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2. EMBO Mol Med. In press [Epub ahead of print]. Abdul-Wahid A, Huang EH, Cydzik. J (2014) The carcinoembryonic. Like N domain plays a critical role in the implantation of metastatic tumor cells. Mol Oncol. Antigen. Mol Oncol. S, Gari é.
Jean Gariépy Research Laboratory - Combinatorial Libaries
http://www.jeangariepy.com/biotherapeutics.html
Development of novel wt-like p53 tumor suppressor variants for cancer gene therapy. Homo-tetramers with wt p53 activity ( blue. Can bind DNA to transactivate p53-target genes. Within cancer cells, endogenous mutant p53 ( red. 1) Poon GMK, Brokx RD, Sung M, Gari é. Py J (2007) Tandem dimerization of the human p53 tetramerization domain stabilizes a primary dimer intermediate and dramatically enhances its oligomeric stability. J Mol Biol,. 2) Brokx RD, Bolewska-Pedyczak E, Gari é. J Biol Chem,.
Jean Gariépy Research Laboratory - Combinatorial Libaries
http://www.jeangariepy.com/toxin.html
Exotoxin A and a schematic of the polypeptide chain divided into its three domains. Image modified from: Wedekind. Journal of Molecular Biology. The hypothetical routing pathway of. Exotoxin A into susceptible cells. 1) Mohammed AF, Abdul-Wahid A, Huang EH, Bolweska-Pedyczak. M, Broad AE, Gari é. J (2012) The Pseudomonas aeruginosa. Domain facilitates the routing of CPP-protein cargos to the cytosol. 2) McCluskey AJ, Poon GM, Bolewska-Pedyczak E, Srikumar T, Jeram SM, Raught B, Gariépy J. (2008) The ...
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Jean Gariépy Research Laboratory - Department of Medical Biophysics, University of Toronto and the Ontario Cancer Institute
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