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K4DD

The goal of the K4DD project is to improve our understanding of how potential drugs bind with their target, and develop methods and tools to allow researchers to study drug-target interactions with greater ease.

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K4DD | k4dd.eu Reviews
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The goal of the K4DD project is to improve our understanding of how potential drugs bind with their target, and develop methods and tools to allow researchers to study drug-target interactions with greater ease.
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K4DD | k4dd.eu Reviews

https://k4dd.eu

The goal of the K4DD project is to improve our understanding of how potential drugs bind with their target, and develop methods and tools to allow researchers to study drug-target interactions with greater ease.

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K4DD: Home

K4DD - Kinetics for Drug Discovery. This webinterface allows you as a scientist to upload your experimental data to the K4DD servers. The K4DD project is supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) under grant agreement n° [115366], resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies' in kind contribution. Contact: bernhard.knasmueller (at) univie.ac.at.

INTERNAL PAGES

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1

People: K4DD

http://www.k4dd.eu/about-k4dd/people.html

K4DD 2017 Berlin Meeting. Linking to the clinic. K4DD 2017 Berlin Meeting. Meet the K4DD researchers. Learn more about the K4DD researchers by selecting organization in the left hand column. The K4DD project is supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) under grant agreement n [115366], resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in kind contribution.

2

K4DD enters 2017 with the acceptance of another public private publication: K4DD

http://www.k4dd.eu/about-k4dd/news/news-detail/item/k4dd-enters-2017-with-the-acceptance-of-another-public-private-publication.html

K4DD 2017 Berlin Meeting. Linking to the clinic. K4DD 2017 Berlin Meeting. K4DD enters 2017 with the acceptance of another public private publication. K4DD got off to a good start in 2017: we are happy to report the acceptance of another joint public-private research article ( Hothersall et al., 2017. Check out Indira's and Daniels publications here. In the final year of the K4DD project we expect many highlights, amongst them will be the PhD thesis defenses of multiple K4DD fellows. Stay tuned!

3

News: K4DD

http://www.k4dd.eu/about-k4dd/news.html

K4DD 2017 Berlin Meeting. Linking to the clinic. K4DD 2017 Berlin Meeting. K4DD Scientific Meeting: "Binding kinetics: Time is of the essence". On 16-18 October, K4DD will organize an open scientific meeting. The meeting will be hosted by K4DD coordinator Bayer in Berlin, Germany. Read more. K4DD enters 2017 with the acceptance of another public private publication. K4DD pharmacologists find new ways to predict the duration of drug effects. K4DD member organizes EFMC course. With a recent publication in ...

4

Publications: K4DD

http://www.k4dd.eu/about-k4dd/publications.html

K4DD 2017 Berlin Meeting. Linking to the clinic. K4DD 2017 Berlin Meeting. Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics. Hothersall JD, Guo D, Sarda S, Sheppard RJ, Chen H, Keur W, Waring MJ, IJzerman AP, Hill SJ, Dale IL and Rawlins PB. Kinetic Profile of Neuropeptide Receptor Interactions. Nederpelt I, Bunnik J, IJzerman AP, and Heitman LH. Journal of Medicinal Chemistry. Guo D, Heitman LH, IJzerman AP. Trends in Pharm...

5

Linking to the clinic: K4DD

http://www.k4dd.eu/k4dd-strategy/linking-to-the-clinic.html

K4DD 2017 Berlin Meeting. Linking to the clinic. Linking to the clinic. Workpackage 3: Link to the clinic: building the models to improve prediction of the kinetics of drug effect in humans. Understanding the interaction of drug molecules with their protein targets is important to predict how fast a drug effect will (dis)appear in a patient. Drug-target binding kinetics are mostly measured in vitro. To select the best drug candidates ( WP1. However, to predict a clinical drug effect from in vitro. It is ...

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Label-free Molecular Interactions : May 2015

http://gedipia.blogspot.com/2015_05_01_archive.html

The latest in label-free molecular Interactions. Tuesday, 19 May 2015. 10th Annual CHI Drug Discovery 2015 Conference Summary. Last month I attended the 10. Annual CHI Drug Discovery 2015 Conference. The only track that dates back to the inception of the conference in 2006 is the FBDD one, making this the oldest recurring fragment conference in the world. Like the conference,. From Harren Jhoti, cofounder and CEO of Astex (acquired by Otsuka in 2013 for $886M) gave a retrospective on FBDD at Astex and th...

db.k4dd.eu db.k4dd.eu

K4DD: Users

https://db.k4dd.eu/help/overview

K4DD - Kinetics for Drug Discovery. Please enter your email and password. I forgot my password. Contact: bernhard.knasmueller (at) univie.ac.at.

pharminfo.univie.ac.at pharminfo.univie.ac.at

Pharmacoinformatics Research Group » Projects

http://pharminfo.univie.ac.at/projects

Faculty of Life Sciences. Open PHACTS: Open Pharmacological Concepts Triple Store. ETOX: A better prediction of toxic effects of new drug candidates. K4DD: Kinetics for Drug Discovery. SFB35: Transmembrane Transporters in Health and Disease. MolTag: Molecular Drug Targets. EU-ToxRisk: An Integrated European 'Flagship' Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century. Univ-Prof. Dr. Gerhard F. Ecker. Department für Pharmazeutische Chemie.

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K4DD

Linking to the clinic. We want to discover design principles that help us in fine-tuning the kinetic parameters of a lead compound. Prof A. IJzerman. We have one big goal:. A better understanding of binding kinetics! Kinetics for Drug Discovery. Why invest 21 million to understand how potential drugs interact with their disease target? The nature of the disease dictates a drug interacts with its target for a relatively short period of time or for a more prolonged duration. This website reflects only the ...

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