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Pharmagellan LLC

Pharmagellan reveals the true value in your biotech development pipeline. Biotech companies typically develop deep research portfolios, but many promising early-stage projects don't progress if the team is stretched thin and focused on the lead asset. To fully realize the value of projects under development, these companies need external support that is both senior-level and hands-on. Pharmagellan offers just that: expert advice and project execution to biotech companies willing to discover how far they can

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Pharmagellan reveals the true value in your biotech development pipeline. Biotech companies typically develop deep research portfolios, but many promising early-stage projects don't progress if the team is stretched thin and focused on the lead asset. To fully realize the value of projects under development, these companies need external support that is both senior-level and hands-on. Pharmagellan offers just that: expert advice and project execution to biotech companies willing to discover how far they can
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Pharmagellan LLC | pharmagellan.com Reviews

https://pharmagellan.com

Pharmagellan reveals the true value in your biotech development pipeline. Biotech companies typically develop deep research portfolios, but many promising early-stage projects don't progress if the team is stretched thin and focused on the lead asset. To fully realize the value of projects under development, these companies need external support that is both senior-level and hands-on. Pharmagellan offers just that: expert advice and project execution to biotech companies willing to discover how far they can

INTERNAL PAGES

pharmagellan.com pharmagellan.com
1

Team — Pharmagellan LLC

http://www.pharmagellan.com/team

Frank S. David, MD, PhD. Frank is a seasoned physician-scientist and corporate strategist at the intersection of business, clinical medicine and basic research. He focuses on helping established and emerging biomedical companies, entrepreneurs, and investors unlock the financial and strategic value of innovative R&D. A multi-pharma consortium to promote best practices in medical publishing, garnered Leerink the Communiqué Trust and Reputation Award in pharma communications. The Pharmagellan Guide to Biot...

2

Blog — Pharmagellan LLC

http://www.pharmagellan.com/blog?category=Policy

New data in the FDA deregulation debate. February 13, 2017. Reciprocal approval sounds appealing, but new data suggest its potential clinical benefits may be overstated. And a free bonus chapter from our book:. Projecting Market Share for R&D-Stage Biotechs. We respect your privacy. Just one more step . Please look for an email from us and confirm your subscription. Projecting Market Share for R&D-Stage Biotechs. A chapter from our book - absolutely free! Send it to me! We respect your privacy.

3

Why Pharma Undervalues Novel R&D — Pharmagellan LLC

http://www.pharmagellan.com/blog/launch-curves

Why Pharma Undervalues Novel R&D. December 10, 2016. This post originally appeared on Forbes.com. On December 7, 2016.]. Why do pharma firms sometimes prioritize me-too R&D projects over high-risk, high-reward pioneer programs? One reason not the only one, but a contributor is that many pharma financial models. According to a new paper by me and Seth Robey. Disclosure and shameless self-promotion: We did this study as part of the work on our new book,. Despite this work’s old and limited sample set, Baue...

4

New data in the FDA deregulation debate — Pharmagellan LLC

http://www.pharmagellan.com/blog/reciprocal-approval

New data in the FDA deregulation debate. February 13, 2017. This post originally appeared on Forbes.com. On February 9, 2017.]. The Trump administration has pledged to [cut] the red tape. At the FDA and streamlin[e] the process. For drug approvals, and there’s a full lineup of agency critics. Auditioning to lead it so we’re likely to hear many ideas. To lower the bar for Americans to access new therapies. But what would the clinical impact of these proposals be? Forcing the FDA to automatically green-lig...

5

Research — Pharmagellan LLC

http://www.pharmagellan.com/pubs

Our research spans a broad range of topics relevant to the biopharma industry, and has led to several peer-reviewed articles. For more information about our research activities or reprints of paywalled papers, contact us a. POTENTIAL CLINICAL IMPACT OF "RECIPROCAL APPROVAL" LEGISLATION. Article in BMJ Open. Feb, 2017; open access). Blog post about the key findings. Drug launch curves in the modern era. Article in Nature Reviews Drug Discovery. Jan, 2017; email for reprint. Blog post about the key findings.

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Battling antimicrobial resistance, visualizing data, and value in health. - INSIGHTS WEEKLY by Ugly Research

http://insights.uglyresearch.com/2016/09/dentists-antibiotics-epi-pen-bayesian.html

Laquo; Social determinants of health, nonfinancial performance metrics, and satisficers. Social program science, gut-bias decision test, and enough evidence already. ». Battling antimicrobial resistance, visualizing data, and value in health. Board of the Week : Dentists will slow down on antibiotics if you show them a chart of their prescribing numbers. Peer-reviewed: An Audit and Feedback Intervention for Reducing Antibiotic Prescribing in General Dental Practice. From the authors: "The feedback provid...

insights.uglyresearch.com insights.uglyresearch.com

INSIGHTS WEEKLY by Ugly Research: healthcare & health tech

http://insights.uglyresearch.com/healthcare-evidence-based-medicine-healthit

35 posts categorized "healthcare and health tech". Social program science, gut-bias decision test, and enough evidence already. The driving force behind MDRC is a conviction that reliable evidence, well communicated, can make an important difference in social policy." -Gordon L. Berlin, President, MDRC. 1 Slice of the week. Can behavioral science improve the delivery of child support programs? Not to discount the excellent work by @CABS MDRC. A commitment to using best evidence to support decision making.

placebocontrol.com placebocontrol.com

Placebo Control: June 2013

http://www.placebocontrol.com/2013_06_01_archive.html

A review of key issues in pharmaceutical clinical trials. Friday, June 21, 2013. Preview of Enrollment Analytics: Moving Beyond the Funnel (Shameless DIA Self-Promotion, Part 2). Are we looking at our enrollment data in the right way? I will be chairing a session on Tuesday on this topic, joined by a couple of great presenters (Diana Chung from Gilead and Gretchen Goller from PRA). Here's a short preview of the session:. Hope to see you there. It should be a great discussion. June 25, 1:45PM - 3:15PM.

placebocontrol.com placebocontrol.com

Placebo Control: Waiver of Informed Consent - proposed changes in the 21st Century Cures Act

http://www.placebocontrol.com/2015/07/waiver-of-informed-consent-proposed.html

A review of key issues in pharmaceutical clinical trials. Tuesday, July 14, 2015. Waiver of Informed Consent - proposed changes in the 21st Century Cures Act. Adam Feuerstein points out - and expresses considerable alarm over - an overlooked clause in the 21. Waive informed consent requirement for clinical trials? Unbelievable but true if #Path2Cures. Becomes law. pic.twitter.com/dqmWPpxPdE. 8212; Adam Feuerstein (@adamfeuerstein) July 14, 2015. The act may, in fact, be helpful in those situations. Secti...

placebocontrol.com placebocontrol.com

Placebo Control: January 2013

http://www.placebocontrol.com/2013_01_01_archive.html

A review of key issues in pharmaceutical clinical trials. Friday, January 25, 2013. Less than Jaw-Dropping: Half of Sites Are Below Average. Last week, the Tufts Center for the Study of Drug Development unleashed the latest. In their occasional series of dire pronouncements about the state of pharmaceutical clinical trials. One particular factoid from the CSDD "study" caught my attention:. 57% of these racers won't medal! Many industry reporters uncritically recycled those numbers. Pharmalot. If you beli...

placebocontrol.com placebocontrol.com

Placebo Control: March 2014

http://www.placebocontrol.com/2014_03_01_archive.html

A review of key issues in pharmaceutical clinical trials. Tuesday, March 18, 2014. These Words Have (Temporarily) Relocated. Near the end of last year, I had the bright idea of starting a second blog,. To capture a lot of smaller items that I found interesting but wasn't going to work up into a full-blown, 1000 word post. First, my team at CAHG Trials. Launched a new blog,. FPI is dedicated to an open discussion of patient recruitment ideas, and I’m extremely proud of what we've published so far. My inau...

placebocontrol.com placebocontrol.com

Placebo Control: January 2014

http://www.placebocontrol.com/2014_01_01_archive.html

A review of key issues in pharmaceutical clinical trials. Sunday, January 12, 2014. Megafund versus Megalosaurus: Funding Drug Development. This new 10-minute TEDMED talk is getting quite a bit of attention:. If embedded video does not work, try the TED site itself. In it, Roger Stein claims to have created an approach to advancing drugs through clinical trials that will "fundamentally change the way research for cancer and lots of other things gets done". 9 billion estimated 2013 R&D spend. Many times m...

placebocontrol.com placebocontrol.com

Placebo Control: June 2014

http://www.placebocontrol.com/2014_06_01_archive.html

A review of key issues in pharmaceutical clinical trials. Tuesday, June 10, 2014. I have to admit to maybe being a little unsure about the " Dpharm: Disruptive Innovations to Advance Clinical Trials. A more cynical man than I might look at the high entry price, the posh venue, and the perhaps-somewhat-predictable list of long-time pharma insiders presenting and think: is this really the group that is going to change the status quo in clinical trials, or is this the group that created. Last year's 5/5 whi...

placebocontrol.com placebocontrol.com

Placebo Control: July 2015

http://www.placebocontrol.com/2015_07_01_archive.html

A review of key issues in pharmaceutical clinical trials. Tuesday, July 14, 2015. Waiver of Informed Consent - proposed changes in the 21st Century Cures Act. Adam Feuerstein points out - and expresses considerable alarm over - an overlooked clause in the 21. Waive informed consent requirement for clinical trials? Unbelievable but true if #Path2Cures. Becomes law. pic.twitter.com/dqmWPpxPdE. 8212; Adam Feuerstein (@adamfeuerstein) July 14, 2015. The act may, in fact, be helpful in those situations. Secti...

placebocontrol.com placebocontrol.com

Placebo Control: September 2013

http://www.placebocontrol.com/2013_09_01_archive.html

A review of key issues in pharmaceutical clinical trials. Wednesday, September 25, 2013. Brave New Biopharm Blogging. Although a few articles on this site are older, I really only began blogging in earnest about 15 months ago. However, I suppose that's long enough that I can count myself as at least somewhat established, and take a moment to welcome and encourage some interesting newcomers to the scene. The Big Pharma insider. Frank also gets my vote for most under-followed Twitter account. Clinical oper...

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Our biotech finance handbook is now available! Discover how far you can go. Our biotech finance handbook is now available! Our biotech finance handbook is now available! Now available on amazon! THE PHARMAGELLAN GUIDE TO BIOTECH FORECASTING AND VALUATION. Is the one-stop reference you need, whether you’re making investment decisions, pitching to potential partners, or estimating the value of an R&D program. Vetted benchmarks for key drivers of income, expenses, and valuation. Buy it on amazon. Early clin...

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