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Home | Structural Bioinformatics and Network Biology Group

Skip to main content. Structural Bioinformatics and Network Biology Group. DSysMap: Exploring the edgetic role of disease mutations. Mosca et al, Nature Methods, 2015. Analysis of chemical and biological features yields mechanistic insights into drug side effects. Duran-Frigola and Aloy, Chemistry and Biology, 2013. Interactome3D: adding structural details to protein networks. Mosca et al, Nature Methods, 2013. Assessing the applicability of template-based protein docking in the twilight zone. SBNB recei...

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Home | Structural Bioinformatics and Network Biology Group | sbnb.irbbarcelona.org Reviews

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Skip to main content. Structural Bioinformatics and Network Biology Group. DSysMap: Exploring the edgetic role of disease mutations. Mosca et al, Nature Methods, 2015. Analysis of chemical and biological features yields mechanistic insights into drug side effects. Duran-Frigola and Aloy, Chemistry and Biology, 2013. Interactome3D: adding structural details to protein networks. Mosca et al, Nature Methods, 2013. Assessing the applicability of template-based protein docking in the twilight zone. SBNB recei...

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3did: a catalogue of domain-based interactions of known three-dimensional structure | Structural Bioinformatics and Network Biology Group

http://sbnb.irbbarcelona.org/3did_2013

Skip to main content. 3did: a catalogue of domain-based interactions of known three-dimensional structure. Stein A, Olivella R. Nucleic Acids Research, 2014. 42 (D1), D374-D379. The database of three-dimensional (3D) interacting domains (3did, available online for browsing and bulk download at http:/ 3did.irbbarcelona.org. Direct link: 10.1093/nar/gkt887. Last updated 03 May 2016 10:39 am.

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dSysMap: mapping mutations on the human structural interactome | Structural Bioinformatics and Network Biology Group

http://sbnb.irbbarcelona.org/node/130

Skip to main content. DSysMap: mapping mutations on the human structural interactome. DSysMap (which stands for Disease-mutations Systemic Mapping ) is a computational tool to interpret the effect of genetic mutations on the development of complex diseases by mapping them to the human structural interactome. dSysMap allows to display mutations in the systemic context of the human interactome and to identify their potential "edgetic" effects. Http:/ dsysmap.irbbarcelona.org.

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Charting the molecular links between driver and susceptibility genes in colorectal cancer | Structural Bioinformatics and Network Biology Group

http://sbnb.irbbarcelona.org/node/99

Skip to main content. Charting the molecular links between driver and susceptibility genes in colorectal cancer. Berenguer C, Soler-López M. Biochem. Biophys. Res. Commun, 2014. 445(4), 734 738. Direct link: 10.1016/j.bbrc.2013.12.012. Last updated 03 May 2016 10:39 am.

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A chemo-centric view of human health and disease | Structural Bioinformatics and Network Biology Group

http://sbnb.irbbarcelona.org/node/117

Skip to main content. A chemo-centric view of human health and disease. Rossell D, Aloy P. Nature Communications, 2014. Direct link: 10.1038/ncomms6676. Last updated 03 May 2016 10:39 am.

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Assessing the applicability of template-based protein docking in the twilight zone | Structural Bioinformatics and Network Biology Group

http://sbnb.irbbarcelona.org/node/112

Skip to main content. Assessing the applicability of template-based protein docking in the twilight zone. 22(9), 1356 1362. Direct link: 10.1016/j.str.2014.07.009. Last updated 03 May 2016 10:39 am.

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dsysmap.irbbarcelona.org dsysmap.irbbarcelona.org

dSysMap - About

http://dsysmap.irbbarcelona.org/about.php

DsysMap is provided by the Structural Bioinformatics and Network Biology Group. At the Institute for Research in Biomedicine. Mosca R, Tenorio-Laranga J, Olivella R, Alcalde V, Céol A, Soler-López M and Aloy P. DSysMap: exploring the edgetic role of disease mutations. 2015, Nature Methods, 12:167-168, doi:10.1038/nmeth.328. Http:/ dsysmap.irbbarcelona.org. For any question or suggestion please send an email to dsysmap. Last modified: 27 February 2015.

3did.irbbarcelona.org 3did.irbbarcelona.org

3did - Browse

http://3did.irbbarcelona.org/browse.php

All domains starting with. Ribosomal S10 LIG 2-0. Hormone recep LIG 1-0. Ribosomal S11 LIG 5-0. RNA pol L LIG 0-0. Ribosomal S10 LIG 2-1. SHS2 Rpb7-N LIG 0-0. Ribosomal S10 LIG 5-0. All motifs starting with. Browse by GO term. Is provided by the Structural Bioinformatics and Network Biology Group. At the Institute for Research in Biomedicine. For any question/suggestion. Last modified: 02 January 2014.

3did.irbbarcelona.org 3did.irbbarcelona.org

3did - Help

http://3did.irbbarcelona.org/help.php

The database of 3D Interaction Domains ( 3did. Is a collection of domain-domain interactions in proteins for which high-resolution three-dimensional structures are known. 3did. Those instances where the motif is significantly enriched in model species interactomes are included in 3did. To retrieve information on a domain, use the Domain query in the Search page. You can give the exact domain name, or just part of it. If no exact match is found, 3did. You can give the exact name of the motif, or just part...

3did.irbbarcelona.org 3did.irbbarcelona.org

3did - Download

http://3did.irbbarcelona.org/download.php

The flat files downloadable here contain the core information of 3did. Contains interacting domain pairs (ID) and instances of these interactions in PDB structures along with InterPreTS scores (Aloy and Russell, Bioinformatics 2003). And details on the contacts;. 3did dmi flat.gz. Contains domain-motif interactions, i.e. motifs with the corresponding pattern and source database as well as all 3D instances of the interaction type;. 3did interface flat.gz. 3did global interface flat.gz. Domain (source data...

interactome3d.irbbarcelona.org interactome3d.irbbarcelona.org

Interactome3D - Statistics

http://interactome3d.irbbarcelona.org/statistics.php

Versions of source databases. Statistics on proteins (Ver. 2016 06). Statistics on interactions (Ver. 2016 06). The contents of Interactome3D. Is based on the following databases:. Statistics on proteins (Ver. 2016 06) [top]. Statistics on interactions (Ver. 2016 06) [top]. Growth of Interactome3D [top]. Interactome3D is provided by the Structural Bioinformatics and Network Biology Group. At the Institute for Research in Biomedicine. And requires the latest version of Adobe Flash Player.

interactome3d.irbbarcelona.org interactome3d.irbbarcelona.org

Interactome3D - Results

http://interactome3d.irbbarcelona.org/results.php?queryid=bsubtilis

Results for dataset: Bacillus subtilis. Query interactions with proteins. Enter a list of Uniprot ACs:. For example. A0A5B9 P01848 A0AQH0 O61443. Number of unique interactions. With an experimental structure. With a model (generic PDB template). With a model (domain-domain template from 3did. Total with structural data (structure or model). Available for docking (see help. Number of unique proteins in interactome. With a complete exp. structure. With a complete homolgy model. Browse by GO term.

interactome3d.irbbarcelona.org interactome3d.irbbarcelona.org

Interactome3D - About

http://interactome3d.irbbarcelona.org/about.php

Interactome3D is provided by the Structural Bioinformatics and Network Biology Group. At the Institute for Research in Biomedicine. For any question or suggestion please send an email to interactome3d. Interactome3D is provided by the Structural Bioinformatics and Network Biology Group. At the Institute for Research in Biomedicine. For any question/suggestion. The Interactome3D website is powered by Cytoscape Web. And requires the latest version of Adobe Flash Player. Last modified: 06 November 2013.

interactome3d.irbbarcelona.org interactome3d.irbbarcelona.org

Interactome3D - Download

http://interactome3d.irbbarcelona.org/download.php

You can download complete and representative datasets for complete organisms from the following links:. Synechocystis sp. (strain PCC 6803 / Kazusa). Interactome3D is provided by the Structural Bioinformatics and Network Biology Group. At the Institute for Research in Biomedicine. For any question/suggestion. The Interactome3D website is powered by Cytoscape Web. And requires the latest version of Adobe Flash Player. Last modified: 01 August 2014.

interactome3d.irbbarcelona.org interactome3d.irbbarcelona.org

Interactome3D

http://interactome3d.irbbarcelona.org/index.php

Interactome3D is a web service for the structural annotation of protein-protein interaction networks. Submit your interactions and the server will find all the available structural data for both the single interactors and the interactions themselves. Additionally you can also visualize and download structural information for interactions involving a set of proteins or interactomes for one of the precalculated organisms. If you have any doubts read our section of Frequently Asked Questions. By clicking th...

interactome3d.irbbarcelona.org interactome3d.irbbarcelona.org

Interactome3D - Help

http://interactome3d.irbbarcelona.org/help.php

Format of the downloadable files. Here you can find a series of very short video tutorials that will guide you through the basic functionalities of the Interactome3D web service. Submit your data and check the results. Browse Interactome3D pre-built datasets. Query with a list of proteins. You can also follow our step-by-step tutorials:. Submit your data and check the results. Browse Interactome3D pre-built datasets. Query Interactome3D with a list of proteins. Page displays details about the protein, in...

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Home | Structural Bioinformatics and Network Biology Group

Skip to main content. Structural Bioinformatics and Network Biology Group. DSysMap: Exploring the edgetic role of disease mutations. Mosca et al, Nature Methods, 2015. Analysis of chemical and biological features yields mechanistic insights into drug side effects. Duran-Frigola and Aloy, Chemistry and Biology, 2013. Interactome3D: adding structural details to protein networks. Mosca et al, Nature Methods, 2013. Assessing the applicability of template-based protein docking in the twilight zone. SBNB recei...

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