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4DN Portal - HOME

​ The Common Fund’s 4D Nucleome program  aims to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular...

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4DN Portal - HOME | 4dnucleome.org Reviews
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​ The Common Fund’s 4D Nucleome program  aims to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular...
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4DN Portal - HOME | 4dnucleome.org Reviews

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​ The Common Fund’s 4D Nucleome program  aims to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular...

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1

Annual Meetings - 4DN Portal

http://www.4dnucleome.org/annual-meetings.html

2

External Advisors - 4DN Portal

http://www.4dnucleome.org/external-advisors.html

Marisa Bartolomei, Ph.D. Professor of Cell and Developmental Biology. Perelman School of Medicine. Cherry, Ph.D. Tom Gingeras, Ph.D. Cold Spring Harbor Laboratory. Gary Karpen, Ph.D. Division Director/Life Sciences Division. Lawrence Berkeley National Laboratory. Scientist, Assistant Professor. Princess Margaret Cancer Centre / University Health Network. University of Toronto, Department of Medical Biophysics. Aviv Regev, Ph.D. Core Member, Broad Institute. Investigator, Howard Hughes Medical Institute.

3

Protocols - 4DN Portal

http://www.4dnucleome.org/protocols.html

Enomic technologies currently in use or being developed in the 4DN network. 4DN Steering Committee approved protocols. February 21, 2017. Standards and Guidelines for Hi-C experiments. February 21, 2017. Protocol and Quality Control Standards for in situ Hi-C experiments. Capturing Chromosome Conformation (Dekker et al, Science, 2002). Chromosome conformation capture techniques. 4C technology: protocols and data analysis (van de Werken et al, Methods Enzymol, 2012). ChIP-based methods for the identificat...

4

Further reading - 4DN Portal

http://www.4dnucleome.org/further-reading.html

Collections of nucleome papers. This is a collection of genome interaction papers. This is a collection of analysis papers.

5

Software - 4DN Portal

http://www.4dnucleome.org/software.html

Data analysis and visualization tools. Here we compiled a list of tools available for data analysis and/or visualization of 4DN-related datasets. If you have any suggestions to add/update this list, please send them to us via email: rcalandrelli@eng.ucsd.edu. AutoChrom3D is an automatic pipeline to model chromatin regions with genomic size ranging from hundreds of kilobases to megabases at 8 kb resolution. A method that jointly calls all centromeres in a genome-wide Hi-C contact map. A deterministic meth...

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Home - 4dnucleome

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4DN Portal - HOME

Welcome to the 4DN Portal. 8203; The Common Fund’s 4D Nucleome program. Aims to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect normal development as well as various diseases.

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