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CENTRIFUGATION
Principles of centrifugation, industrial centrifugal filters and centrifugal sedimenters. APPLICATIONS OF CENTRIFUGATION IN PHARMACEUTICAL INDUSTRIES. 1 Production of bulk drugs. After crystallization the drugs are separated from the mother liquor by centrifugation. For example traces of mother liquor is separated from aspirin crystals by centrifugation method. 2 Production of biological products. 3 Evaluation of suspensions and emulsions. 4 Determination of molecular weight of colloids. M they undergo B...
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CRYSTALLIZATION
Introduction, importance. Theory – nucleation, crystal growth, Mier’s theory. Classification, principles underlying the design and operation of Swenson-Walker, Krystal, Vacuum and growth type of crystallisers. Study of different operation variables in the vacuum and growth type crystallizers. Discuss the Mier’s theory of crystallization. (2000) [8]. Describe the design and operation of Krystal crystalliser. (2000) [8]. What are the different types of nucleation. How are nucleation rates predicted? Crysta...
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INTRODUCTION TO BIOPHARMACEUTICS AND PHARMACOKINETICS
INTRODUCTION TO BIOPHARMACEUTICS AND PHARMACOKINETICS. Introduction to biopharmaceutics and pharmacokinetics. Introduction to biopharmaceutics and pharmacokinetics and their role in information development and clinical setting. Biopharmaceutics can be defined as the study of the. Interrelationship of the physicochemical properties of the drug,. The dosage form in which the drug is given,. And the route of administration. On the rate and extent (amount) of systemic drug absorption. The theoretical aspect ...
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