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ABREGEN.COM

AbRegen Pty Ltd

AbRegen Pty Ltd is a preclinical stage biotechnology company that specialises in the development of antibody-based therapeutics for tissue repair applications.

http://www.abregen.com/

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'Cowin'

AbRegen Pty Ltd

1/190 ●●●●●●ton Rd

Du●●ch , SA, 5065

AUSTRALIA

6108●●●●5018
al●●●●●●●●●●●@unisa.edu.au

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Cowin

Allison Cowin

1/190 ●●●●●●ton Rd

Du●●ch , SA, 5065

AUSTRALIA

6108●●●●5018
al●●●●●●●●●●●@unisa.edu.au

View this contact

Cowin

Allison Cowin

1/190 ●●●●●●ton Rd

Du●●ch , SA, 5065

AUSTRALIA

6108●●●●5018
al●●●●●●●●●●●@unisa.edu.au

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AbRegen Pty Ltd | abregen.com Reviews
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AbRegen Pty Ltd is a preclinical stage biotechnology company that specialises in the development of antibody-based therapeutics for tissue repair applications.
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AbRegen Pty Ltd | abregen.com Reviews

https://abregen.com

AbRegen Pty Ltd is a preclinical stage biotechnology company that specialises in the development of antibody-based therapeutics for tissue repair applications.

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1

AbRegen Pty Ltd

http://www.abregen.com/publications

1 Cowin AJ, Adams DH, Strudwick XL, Chan H, Hooper JA, Sander GR, Rayner TE, Matthaei KI, Powell BC, Campbell HD (2007) Flightless I deficiency enhances wound repair by increasing cell migration and proliferation. Journal of Pathology 211(5):572-581. 2 Kopecki Z, and Cowin AJ (2007) Flightless I: An actin-remodelling protein and an important negative regulator of wound repair. International Journal of Biochemistry and Cell Biology 40(8):1415-9. 5 Adams DH, Ruzehaji N, Strudwick XL, Greenwood JE, Campbell...

2

AbRegen Pty Ltd

http://www.abregen.com/flightless_I

Flightless I (Flii) is a novel drug target that regulates important cellular behaviours including mobility, contraction, adhesion, proliferation and cytokine production. The activity of Flii is mediated through interaction with components of the cell’s cytoskeleton, modulation of intracellular signalling pathways and regulation of cellular transcription events. Gene was originally identified in Drosophila melanogaster. And a murine model of epidermolysis bullosa. In addition, administration of anti-Fligh...

3

AbRegen Pty Ltd

http://www.abregen.com/news

2014 AbRegen Pty Ltd.

4

AbRegen Pty Ltd

http://www.abregen.com/therapeutic_focus

Inherited EB is caused by mutations to structural proteins in the skin. Patients with dystrophic EB have mutations within the gene for type VII collagen, resulting in deficient or absent anchoring fibrils. Separation of the epidermis from the dermis can occur with even minor trauma, resulting in blister formation. For further information on EB:. 2014 AbRegen Pty Ltd.

5

AbRegen Pty Ltd

http://www.abregen.com/zh

AbRegen 正在着手开发的项目是寻找依托抗体 anti-Flightless I 的治疗方法,主要针对一系列以肌肤脆弱以及水疱反复出现 表皮溶解水疱症 为特征的先天性遗传紊乱疾病。 澳大利亚南澳州锡巴顿区西锡巴顿路 40-46号, 邮编 5031. 澳大利亚营业许可号 ABN) 38 129 282 800. 邮箱 10065, 阿德莱德商业中心, 南澳阿德莱德 5000, 澳大利亚. David Belford 博士, 经理,AbRegen私人有限公司. 2014 AbRegen Pty Ltd.

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AbRegen Pty Ltd

AbRegen is a preclinical stage biotechnology company that specialises in the development of antibody-based therapeutics for tissue repair applications. AbRegen owns a broad intellectual property portfolio related to the modulation of Flightless I, a key regulator of cell growth and migration. The technology has application to disorders of cellular movement and proliferation, including non-healing chronic wounds, burn injury, cancer and fragile skin disorders. 2014 AbRegen Pty Ltd.

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