ActiveSite Pharmaceuticals utilizes proprietary lead discovery technology to discover new small molecule drug candidates (NCEs) for human diseases with unmet medical need. Our initial efforts are focused on developing novel, innovative treatments for diabetic macular edema and hemorrhagic stroke by targeting the vascular serine protease plasma kallikrein. Powered by Network Solutions.
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PERFECT PRIVACY, LLC
12808 Gra●●●●●●●●●kway West
Jack●●●●ille , FL, 32258
US
View this contact
PERFECT PRIVACY, LLC
12808 Gra●●●●●●●●●kway West
Jack●●●●ille , FL, 32258
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View this contact
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ActiveSite Pharmaceuticals | activesitepharma.com Reviews
https://activesitepharma.com
ActiveSite Pharmaceuticals utilizes proprietary lead discovery technology to discover new small molecule drug candidates (NCEs) for human diseases with unmet medical need. Our initial efforts are focused on developing novel, innovative treatments for diabetic macular edema and hemorrhagic stroke by targeting the vascular serine protease plasma kallikrein. Powered by Network Solutions.
activesitepharma.com
ActiveSite Pharmaceuticals
http://www.activesitepharma.com/publicationsnews.html
United States Patent 8,691,861. Prodrugs of Inhibitors of Plasma Kallikrein. ActiveSite and Joslin Diabetes Center awarded. United States Patent 8,658,685. Methods for Treatment of Kallikrein-Related Disorders. United States Patent 8,609,866. Prodrugs of Inhibitors of Plasma Kallikrein. United States Patent 8,258,170. Inhibitors of Plasma Kallikrein. ActiveSite Pharmaceuticals’ Announces the Award of a Competitively Renewed Phase II SBIR Grant From the National Institutes of Health,. 60, 1590-98 (2011).
ActiveSite Pharmaceuticals
http://www.activesitepharma.com/founders.html
Sukanto Sinha, Ph.D. Tamie Chilcote, Ph.D. Powered by Network Solutions.
ActiveSite Pharmaceuticals
http://www.activesitepharma.com/plasmakallikrein.html
What is Plasma Kallikrein? Plasma kallikrein is a vascular serine protease, circulating in blood as an inactive zymogen, prekallikrein. Upon activation, plasma kallikrein cleaves its physiological substrate high molecular weight kininogen, generating the potent inflammatory vasodilator peptide bradykinin. Binding of bradykinin to its receptors on the surface of endothelial cells lining blood vessels initiates a series of signaling events leading to the opening of intercellular junctions between e...
ActiveSite Pharmaceuticals
http://www.activesitepharma.com/clinicalindications.html
Diabetic Macular Edema (DME). ActiveSite's Approach to DME and HAE. For HAE, plasma levels of the lead compound readily achieved via once-daily dosing inhibit bradykinin formation more effectively than physiological levels of C1-Inhibitor, providing empirical confirmation of its prophylactic potential. Powered by Network Solutions.
ActiveSite Pharmaceuticals
http://www.activesitepharma.com/home.html
ActiveSite Pharmaceuticals utilizes proprietary lead discovery technology to discover new small molecule drug candidates for human diseases with unmet medical need. Our initial efforts are focused on developing novel, innovative treatments for the major vision-threatening complication of diabetes, diabetic macular edema. And the genetic disease hereditary angioedema. By targeting the vascular protease plasma kallikrein. Powered by Network Solutions.
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Diabetes: June 2011
http://diabposition.blogspot.com/2011_06_01_archive.html
DIABETES CIES SEARCH ENGINE [SELECTED WEBSITES]. ActiveSite Pharmaceuticals : Small Molecule Protea. Sirona Biochem : Scale Up of Compounds to Accelera. The Juvenile Diabetes Research Foundation and Sele. LCT and Otsuka of Japan : Common DIABECELL Visio. Monday, June 27, 2011. ActiveSite Pharmaceuticals : Small Molecule Protease Inhibitor Blocks Retinal Blood Vessel Damage in Rodent Model of Diabetes. March 28, 2011 - ActiveSite Pharmaceuticals, Inc. Publié par Benjamin de Bélizal. Is a privately owned C...
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ActiveSite Pharmaceuticals
ActiveSite Pharmaceuticals utilizes proprietary lead discovery technology to discover new small molecule drug candidates (NCEs) for human diseases with unmet medical need. Our initial efforts are focused on developing novel, innovative treatments for diabetic macular edema and hemorrhagic stroke by targeting the vascular serine protease plasma kallikrein. Powered by Network Solutions.
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