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Welcome to Aileron Therapeutics

Is a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides. Stapled Peptides are a breakthrough solution to address thousands of therapeutically important yet currently undruggable targets. Stapled Peptides have demonstrated their unique ability to penetrate cells throughout the body and modulate protein-protein interactions, critical control points for most human diseases. Aileron is building a robust pipeline of therapeutics. February 12, 2015. Key insights o...

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CONTACTS AT AILERONRX.COM

Aileron Therapeutics, Inc.

Administrator Administrator

840 Me●●●●●● Drive

Cam●●●dge , Massachusetts, 02139

United States

617●●●900
in●●@aileronrx.com

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Aileron Therapeutics, Inc.

Administrator Administrator

840 Me●●●●●● Drive

Cam●●●dge , Massachusetts, 02139

United States

617●●●900
in●●@aileronrx.com

View this contact

Aileron Therapeutics, Inc.

Administrator Administrator

840 Me●●●●●● Drive

Cam●●●dge , Massachusetts, 02139

United States

617●●●900
in●●@aileronrx.com

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Welcome to Aileron Therapeutics | aileronrx.com Reviews
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Is a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides. Stapled Peptides are a breakthrough solution to address thousands of therapeutically important yet currently undruggable targets. Stapled Peptides have demonstrated their unique ability to penetrate cells throughout the body and modulate protein-protein interactions, critical control points for most human diseases. Aileron is building a robust pipeline of therapeutics. February 12, 2015. Key insights o...
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Welcome to Aileron Therapeutics | aileronrx.com Reviews

https://aileronrx.com

Is a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides. Stapled Peptides are a breakthrough solution to address thousands of therapeutically important yet currently undruggable targets. Stapled Peptides have demonstrated their unique ability to penetrate cells throughout the body and modulate protein-protein interactions, critical control points for most human diseases. Aileron is building a robust pipeline of therapeutics. February 12, 2015. Key insights o...

INTERNAL PAGES

aileronrx.com aileronrx.com
1

Aileron Therapeutics : News & Publications

http://www.aileronrx.com/publications.php

Big Pharma Venture Teams Back Aileron's Shift to Early-Stage R&D. Shifting more of its focus to clinical drug development, Cambridge, MA-based Aileron Therapeutics has rounded up $30 million in Series E cash to fund a Phase I/IIa study of its p53-targeted cancer drug candidate. The roster of VC backers includes some of the industry's biggest corporate venture groups- Roche Venture Fund, Novartis Venture Funds, Lilly Ventures and SR One- along with Apple Tree Partners and Excel Venture Management. Aileron...

2

Aileron Therapeutics : News & Publications

http://www.aileronrx.com/publications_scipubs.php

Stapled α helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy. A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers. A stapled p53 helix overcomes HDMX-mediated suppression of p53. Or link to Research Highlight. Nature Reviews Drug Discovery. Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic. Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide. Walensky, L&#...

3

Aileron Therapeutics : Careers

http://www.aileronrx.com/careers.php

In October 2010 Aileron moved into its new state-of-the-art facility in Cambridge, MA. This unique space features a large integrated lab where scientists from all disciplines work together side-by-side to design, produce, and test Stapled Peptides. The additional work spaces and common areas, designed in a Soho Loft style, offer a highly collaborative and fun work environment in the heart of Cambridge’s biotech community. Click Here to See Our Unique Work Environment. Innovative, Flat Organization. Annua...

4

About Aileron Therapeutics : Sitemap

http://www.aileronrx.com/sitemap.php

The Discovery of Stapled Peptides. 2016 Aileron Therapeutics, Inc. 105;nfo@aileronrx.com.

5

Aileron Therapeutics : Therapeutic Programs

http://www.aileronrx.com/programs.php

Aileron is developing a broad and growing pipeline of Stapled Peptide drugs across a range of therapeutic areas, including cancer, endocrine and metabolic diseases, and inflammation. Aileron is advancing our lead oncology program a highly potent, full re-activator of the p53 pathway. With the potential to deliver superior efficacy and safety in a broad spectrum of solid and hematological malignancies. The development candidate entered clinical trials in 2014. 2016 Aileron Therapeutics, Inc.

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venturecapitalreporter.com venturecapitalreporter.com

finance projects

http://www.venturecapitalreporter.com/tag/finance-projects

Get the latest Venture Capital and Angel investors news and info Join Our Mailing List:. Download The Investors Database. Learn how to Raise Capital from Private Investors. Venture capital firms and funds in Europe. 128 Venture Capital Group. Act Venture Capital Ltd. Adelaide Venture Capital Email. Advantages Of Venture Capital. All Stages Venture Capital. More Venture Capital Terms and Topics. Aileron Therapeutics Closes $40 Million Series D Financing. Â We believe that Stapled Peptides could represent ...

appletreepartners.com appletreepartners.com

Apple Tree Partners

http://www.appletreepartners.com/portfolio/detail/aileron-therapeutics

Aileron Therapeutics is developing first-in-class therapeutics based on its proprietary stapled peptide drug platform. ALRN-6924, in Phase 1, is a p53 re-activator for the treatment of cancer, the only p53 molecule in development that targets both MDM2 and MDMX. Aileron Therapeutics Initiates Phase 1 Cancer Study of ALRN-6924 in Advanced Hematologic and Solid Malignancies with Wild Type p53. Aileron Therapeutics Secures $33 Million in Series E. At AACR Annual Meeting. 10 Top Next-Gen Biotech Platforms.

changetack.com changetack.com

Portfolio - Apple Tree Partners

http://www.changetack.com/portfolio-current.php

Developing a breakthrough proprietary peptide technology platform: stapled peptides convert a broad range of therapeutically useful peptides into pharmaceutically tractable molecules. The world-leader in miniaturized left ventricular assist devices. Developing the leading clinical prostate cancer molecule, with three independent mechanisms of action to suppress the disease.

hrbiotechconnect.com hrbiotechconnect.com

HR BioTech Connect » Members

http://hrbiotechconnect.com/members

HR Biotech Connect Home. April 2017 Event with Radford – Submit Your Questions for our Speakers. Building a Mission-Driven Organization: May 16th. Building and Maintaining a Strong Company Culture. December 2014: Spotlight on the Changing OFCCP Regulations. February 2014: Building High Performance Teams. February 2015: Insights into Personal and Team Communication. HR Roundtable Meeting: April 18th. June 2014 Meeting: Responding to Your CFO: Self-Funding and ACA Readiness. BioTech Journey through the Pha...

biohive.net biohive.net

September 2013 | BioHive

http://www.biohive.net/2013_09_01_archive.html

Monday, 2 September 2013. Monday, September 02, 2013. Maintaining a healthy pipeline and a steady revenue stream are on the top of the priority list for pharma and biotech companies. 2013 has been a interesting year so far, with most companies finishing off making their moves in order to defend against the patent cliff, cut costs, or even "redefine" themselves ( Pfizer had begun the cost-cutting exercise in 2010-2011. AstraZeneca continues to buy. So, let's begin.The graph and table below contain the...

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Aileron - Home

8146 One Calais Avenue. Its easy to recruit, but hard to retain. Aileron enables hospitals to retain their most valuable asset. Nurses. By working with the root causes of nurse turnover. To stop the tug of war for nursing staff based on pay and bonuses. To enhance patient outcomes and satisfaction through quality nursing care. To recruit and retain the best doctors who are attracted by a quality nursing staff. For More Information: Call 225.767.7224 or Email: info@aileronprogram.com. Web Hosting by Yahoo!

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Aileron Publishing, LLC. The Awakening of Ancient Echoes. Where echoes never fade . . . 2008 Aileron Publishing, LLC.

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Croom's RC Website. Welcome to the AileronRC hub! Here you will find videos, posts, Scratch builds, info, and generally RC-related topics. Youtube: http:/ www.youtube.com/croom248. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). You are commenting using your WordPress.com account. ( Log Out. You are commenting using your Twitter account. ( Log Out. You are commenting using your Facebook account. ( Log Out.

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Aileron Roadhouse :: Great Outback Hospitality!

Aileron Hotel and Roadhouse. PMB 175 via Alice Springs NT 0872 (135km north of Alice). Ph: (08) 8956 9703 Fax: (08) 8956 9868. Outback hospitality, Aboriginal art gallery, accom: camping, caravan grounds and air-con motel rooms, pool, bbq picnic area, take a walk and view beautiful scenery, stop for fuel, buy some supplies at the store, or for a longer break enjoy some breakfast, lunch or dinner with an icy cold beer in the Glen Maggie bar! Site Design : DUNNART Advertising.

aileronrx.com aileronrx.com

Welcome to Aileron Therapeutics

Is a biopharmaceutical company leading the development of a new class of drugs called Stapled Peptides. Stapled Peptides are a breakthrough solution to address thousands of therapeutically important yet currently undruggable targets. Stapled Peptides have demonstrated their unique ability to penetrate cells throughout the body and modulate protein-protein interactions, critical control points for most human diseases. Aileron is building a robust pipeline of therapeutics. February 12, 2015. Key insights o...

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