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ALEXA: Alternative Expression Analysis

Provides as introduction and entry point for Alternative Expression Analysis (ALEXA) resources developed at the BC Genome Sciences Center of the BC Cancer Agency. Created by Malachi Griffith and Marco A. Marra

http://www.alexaplatform.org/

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ALEXA: Alternative Expression Analysis | alexaplatform.org Reviews
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Provides as introduction and entry point for Alternative Expression Analysis (ALEXA) resources developed at the BC Genome Sciences Center of the BC Cancer Agency. Created by Malachi Griffith and Marco A. Marra
<META>
KEYWORDS
1 Malachi Griffith
2 Marco Marra
3 ALEXA
4 Alternative Expression Analysis
5 Alternative splicing
6 Splicing microarrays
7 Solexa sequencing
8 Illumina sequencing
9 paired-end sequencing
10 gene expression
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ALEXA: Alternative Expression Analysis | alexaplatform.org Reviews

https://alexaplatform.org

Provides as introduction and entry point for Alternative Expression Analysis (ALEXA) resources developed at the BC Genome Sciences Center of the BC Cancer Agency. Created by Malachi Griffith and Marco A. Marra

INTERNAL PAGES

alexaplatform.org alexaplatform.org
1

ALEXA-Seq: Alternative Expression Analysis by Massively Parallel Sequencing

http://www.alexaplatform.org/alexa_seq/index.htm

A brief introduction to alternative expression analysis by massively parallel RNA sequencing. A brief overview of the methods employed in this analysis. Visualize alternative expression in one of 19 data sets with the ALEXA-Seq data viewer. Get ALEXA-Seq annotation databases for eight species, raw data, source code, etc. ALEXA-Seq is a method for using massively parallel paired-end transcriptome sequencing for 'alternative expression analysis'. Nature Methods. 2010 Oct;7(10):843-847. Pubmed.

2

Acknowledgements

http://www.alexaplatform.org/acknowledge.htm

This work was primarily conducted by Malachi Griffith under the supervision of Marco A. Marra. In addition to the authors and funding sources listed below I would like to acknowledge the advice and support of the following people: Joseph Connors, Stephane Flibotte, Steven Jones and Gregg Morin. Development of ALEXA-seq is ongoing by Malachi Griffith and Obi Griffith under the supervision of Elaine Mardis and Joe Gray respectively. And Marco A. Marra. Nature Methods. Feb 2008. 5(2):118. Characterization o...

3

Results generated by application of the ALEXA-Seq approach

http://www.alexaplatform.org/alexa_seq/results.htm

The following table summarizes data sets that have completed analysis by the ALEXA-Seq approach. Additional details for these projects are provided below. Additional projects that are in the process of being analyzed are also listed. Further additional projects are being analyzed externally at others centres, such as the LBL. Life Sciences Division who are currently mirroring this site and using ALEXA-Seq to analyze some of their data: alexa-seq-lbl.org. Currently, updates are being added to the ' Breast.

4

ALEXA: A microarray design platform for Alternative Expression Analysis

http://www.alexaplatform.org/alexa_arrays/index.htm

Feb, 2008: ALEXA is now published in Nature Methods. The purpose of this site is to make the ALEXA platform and supporting materials available to the public. Complete array designs are now available for ten EnsEMBL. Species. Refer to the Designs. Page for more details. Oct, 2007: Updated version of ALEXA (v1.1) released. The updated source code and 'Virtual Machine Appliance' are both available in the Platform. To learn more about the these designs and how they are created, check out the Intro.

5

ALEXA: Alternative Expression Analysis

http://www.alexaplatform.org/index.htm

Oct 2009: Release of the ALEXA-Seq data viewer. Nov 2009: The first data set analyzed can be viewed here: 5-FU resistance. Apr 2010: ALEXA-Seq analysis is now completed for 16 of 19 data sets representing 155 RNA-Seq libraries. See the results. May 2010: Release of ALEXA-Seq code. June 2010: Our collorators at the LBL are using ALEXA-Seq to analyze some of their data: alexa-seq-lbl.org. Click one of the buttons below to jump straight to alternative expression results or search for a specific gene,. We us...

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LINKS TO THIS WEBSITE

genomesciencesinstitute.com genomesciencesinstitute.com

Scientific Data — Canada's Michael Smith Genome Sciences Centre

http://www.genomesciencesinstitute.com/data

Only in current section. The GSC creates and serves many scientific databases, data assets and data services. CEEHRC: Canadian Epigenetics, Environment and Health Research Consortium Platform. C Elegans Gene Expression. For both Chromatin- immunoprecipation Transcription Factors. Sequence files and the associated probability files are also provided. FPC Mapping data files from species we have fingerprinted. Mouse Atlas of Gene Expression. The Mouse Atlas of Gene Expression is a quantitative and comprehen...

bcgsc.ca bcgsc.ca

Scientific Data — Canada's Michael Smith Genome Sciences Centre

http://www.bcgsc.ca/data

Only in current section. The GSC creates and serves many scientific databases, data assets and data services. CEEHRC: Canadian Epigenetics, Environment and Health Research Consortium Platform. C Elegans Gene Expression. For both Chromatin- immunoprecipation Transcription Factors. Sequence files and the associated probability files are also provided. FPC Mapping data files from species we have fingerprinted. Mouse Atlas of Gene Expression. The Mouse Atlas of Gene Expression is a quantitative and comprehen...

genomesciencesinstitute.org genomesciencesinstitute.org

Scientific Data — Canada's Michael Smith Genome Sciences Centre

http://www.genomesciencesinstitute.org/data

Only in current section. The GSC creates and serves many scientific databases, data assets and data services. CEEHRC: Canadian Epigenetics, Environment and Health Research Consortium Platform. C Elegans Gene Expression. For both Chromatin- immunoprecipation Transcription Factors. Sequence files and the associated probability files are also provided. FPC Mapping data files from species we have fingerprinted. Mouse Atlas of Gene Expression. The Mouse Atlas of Gene Expression is a quantitative and comprehen...

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ALEXA: Alternative Expression Analysis

Oct 2009: Release of the ALEXA-Seq data viewer. Nov 2009: The first data set analyzed can be viewed here: 5-FU resistance. Apr 2010: ALEXA-Seq analysis is now completed for 16 of 19 data sets representing 155 RNA-Seq libraries. See the results. May 2010: Release of ALEXA-Seq code. June 2010: Our collorators at the LBL are using ALEXA-Seq to analyze some of their data: alexa-seq-lbl.org. Click one of the buttons below to jump straight to alternative expression results or search for a specific gene,. We us...

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