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Alliance Protein Laboratories Home Page

We specialize in biophysical characterization of proteins

http://www.ap-lab.com/

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Alliance Protein Laboratories

3957 C●●●●●●ancion

Thou●●●●Oaks , CA, 91360

US

1.80●●●●1074
1.80●●●●7252
jp●●●●@MAILWAY.COM

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Alliance Protein Laboratories

Philo, John

3957 C●●●●●●ancion

Thou●●●●Oaks , CA, 91360

US

1.80●●●●1074
1.80●●●●7252
jp●●●●@ap-lab.com

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Alliance Protein Laboratories Home Page | ap-lab.com Reviews
<META>
DESCRIPTION
We specialize in biophysical characterization of proteins
<META>
KEYWORDS
1 contract research
2 consulting
3 protein
4 biophysics
5 purification
6 characterization
7 biosimilars
8 biotechnology
9 analytical ultracentrifugation
10 AUC
CONTENT
Page content here
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select page,contact information,aggregation services,auc services,characterization overview,cd services,characterization examples,characterization methods,consulting,native gels,light scattering services,other related services,purification services,people
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Alliance Protein Laboratories Home Page | ap-lab.com Reviews

https://ap-lab.com

We specialize in biophysical characterization of proteins

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1

AUC Services

http://www.ap-lab.com/AUC_services.htm

Analytical ultracentrifugation (AUC) is a fundamental and powerful tool for studying the size and shape of macromolecules in solution. It is particularly important for characterizing protein aggregation and determining the native state stoichiometry (quaternary structure). It is also a common tool for showing comparability of higher order structure (HOS). Recently APL has pioneered a new sedimentation equilibrium protocol. SV-AUC) and sedimentation equilibrium. APL has two analytical ultracentrifuges: a ...

2

Careers

http://www.ap-lab.com/careers.htm

Senior Scientist, Biophysical Analysis. We are seeking a talented Ph.D.-level scientist with 5 years of post-Ph.D. experience, preferably including some experience in the biotech or pharmaceutical industries, for work in the laboratory. Extensive experience with multiple biophysical and/or spectroscopic methods such as circular dichroism, analytical ultracentrifugation, light scattering, DSC, FTIR, fluorescence, and/or subvisible particle analysis is required; CD and AUC experience strongly preferred.

3

Frequently Asked Questions

http://www.ap-lab.com/faqs.htm

Do you run biophysical analyses under cGMP standards? No, and thus we cannot accept samples of licensed final products for analysis. We of course try to conform to principles of good laboratory practice, but meeting cGMP standards for these biophysical techniques is generally not possible. The software for these instruments is not compliant with 21 CFR Part 11 guidelines, and the protocols have not been formally validated. It is our understanding that characterization data. Who have you worked for? We do...

4

About Our People

http://www.ap-lab.com/people.htm

Tsutomu Arakawa, Ph.D. President and Director of Protein Chemistry. Tsutomu has authored over 340 scientific publications, listed here. Including over 290 directly related to his work in biotechnology and pharmaceuticals. John Philo, Ph.D. Vice President, CFO, and Director of Biophysical Chemistry. John has authored 90 scientific publications, listed here. Including over 70 directly related to biotechnology and pharmaceutical applications. N Karl Maluf, Ph.D. Prior to that Karl did postdoctoral work at U...

5

Circular Dichroism

http://www.ap-lab.com/circular_dichroism.htm

See also our CD services page. Circular dichroism (CD) spectroscopy measures differences in the absorption of left-handed polarized light versus right-handed polarized light which arise due to structural asymmetry. The absence of regular structure results in zero CD intensity, while an ordered structure results in a spectrum which can contain both positive and negative signals. Circular dichroism spectroscopy is particularly good for:. And the structural family to which it belongs. If there are any confo...

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LINKS TO THIS WEBSITE

jphilo.mailway.com jphilo.mailway.com

Links to Biophysics and Protein Chemistry Sites

http://jphilo.mailway.com/links.htm

Quick jumps to: CD. If you find broken links or have suggestion for other sites please contact John Philo). Contract lab offering AUC services (experiments and/or data analysis) to industry and academia; web pages have examples of pharmaceutical applications. Software depot, e-mail list server. U Texas HSC Center for Analytical Ultracentrifugation of Macromolecular Assemblies. Ultrascan software, analysis examples, tutorials. National Analytical Ultracentrifugation Facility. Good AUC reading list. From B...

htlbio.com htlbio.com

Protein Characterizations

http://www.htlbio.com/services/PC.html

Customized Plasmid DNA Preparations. Amino Acid and Vitamin Analysis. At HTL Biosolutions, Inc., we offer both consulting and contract research services on protein characterizations, stability testings and formulation development. In a close alliance with Protein Alliance Laboratory, Inc. We offer a array of comprehensive contract research service in protein characterizations. HPLC including SEC, RP, IEX, and peptide mapping. Gel Electrophoresis including SDS-PAGE, Native and IEF.

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Contact us by e-mail. DSC services and background. Download articles and presentations. Welcome to the Alliance Protein Laboratories, Inc. web site! APL offers contract research services in the areas of protein. And peptide biophysical characterization, protein aggregation, protein purification, and protein stabilization. If you are looking for analytical ultracentrifugation. AUC), circular dichroism. Fluorescence, or native gel. APL has demonstrated a new sedimentation equilibrium protocol. At APL the e...

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