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Apoptosis Research Center - ARC National University Galway

Apoptosis is a way in which the cells in our bodies die when they are damaged or reach the end of their lifespan. linked to diseases such as cancer.

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Apoptosis Research Center - ARC National University Galway | apoptosis.ie Reviews

https://apoptosis.ie

Apoptosis is a way in which the cells in our bodies die when they are damaged or reach the end of their lifespan. linked to diseases such as cancer.

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1

ARC - Apoptosis Research Centre

http://www.apoptosis.ie/facilities.html

Prof Afshin Samali (Director). Flow cytometry and cell sorting. Fluorescence and confocal microscopy. Lentivirus and adenovirus lab.

2

ARC - Apoptosis Research Centre

http://www.apoptosis.ie/adrienne.html

Prof Afshin Samali (Director). Lecturer in Biochemistry, 2000. PhD Trinity College Dublin, Ireland. BAMod Biochemistry, Trinity College Dublin, Ireland. Mechanisms of pro-survival signalling. Mechanisms of nerve growth factor signalling in cell death and survival. Yao L, Damodaran G, Nikolskaya N, Gorman AM, Windebank A, Pandit A (2010) The effect of laminin peptide gradient in enzymatically cross-linked collagen scaffolds on neurite growth. J Biomed Mater Res 92, 484-492. Szegezdi E, Reed Herbert K, Kav...

3

ARC - Apoptosis Research Centre

http://www.apoptosis.ie/apoptosis.html

Prof Afshin Samali (Director). In the adult organism cell number is kept constant by carefully balancing cell division and cell death. Cells have to be replaced when they become old, diseased or infected but cell proliferation must by offset by cell death. If the. Between cell proliferation and cell death is disturbed, for example if. The cells divide faster than they die, tumor formation can occur, or conversely, if cells divide slower than they die this will result in an overall cell loss. Http:/ www&#...

4

ARC - Apoptosis Research Centre

http://www.apoptosis.ie/ralf.html

Prof Afshin Samali (Director). Lecturer Above The Bar, NCBES, NUI Galway. Selection of key publications:. Büneker CK, Yu R, Deedigan L, Mohr A, Zwacka RM. (2012) 'IFN-γ combined with targeting of XIAP leads to increased apoptosis-sensitisation of TRAIL resistant pancreatic carcinoma cells'. Cancer Letters,. Albarenque SM, Zwacka RM, Mohr A. (2011) 'Both human and mouse mesenchymal stem cells promote breast cancer metastasis'. Stem Cell Research. Murray TV, McMahon JM, Howley BA, Stanley A, Ritter T, Mohr...

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ARC - Apoptosis Research Centre

http://www.apoptosis.ie/michael.html

Prof Afshin Samali (Director). Professor of Haematology NUIG 2007. Consultant Haematologist University Hospital Galway 2002. Assistant Professor Leukemia Department , Oregon Health and Sciences University 2002. Hematology Fellow, Oregon Health and Sciences University 1998-2001. Translational research and drug development in haematological malignancies. Selection of recent publications:. Giles FJ, O'Dwyer M, Swords R. Class effects of tyrosine kinase inhibitors in the treatment of chronic myeloid leuk...

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Just the apoptosis research collection. Bcl-2 (B-cell lymphoma 2). MicroRNA-1 Regulates Cardiomyocyte Apoptosis by Targeting Bcl-2. Ubiquitous Expression of Bcl-2 Protein in Mitotic Nuclei and Chromosomes. Gene Expression Analysis of Bcl-2 in Rat Experimental Periapical Lesions. Bcl-2 Completely Blocks Fas-Mediated Apoptosis in mtDNA-Depleted HeLa Cells. Enhanced Expression of Bcl-2 Inhibits Apoptosis in Cultured Human Keratinocytes. TRIM29 negatively regulates p53 via inhibition of Tip60.

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Apoptosis Research Center - ARC National University Galway

Professor Michael O’Dwyer. Research Expertise & Facilities. NEWS & EVENTS. Meetings & Seminars Calendar. Past Events & Conference Reports. PUBLIC ENGAGEMENT & COLLABORATION. The Apoptosis Research Centre is a group of Research Teams located at the Biomedical Sciences Building at NUI, Galway. The Teams work collaboratively to investigate the mechanisms of cell death in a range of diseases, with a particular focus on cancers. A Message From the Director. A Message From the Director. Dr Susan Logue receives...

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