ArthritoMab Antibody Cocktail for the induction of a shorter, more synchronized alternative to the collagen-induced arthritis (CIA) model.
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ArthritoMab Antibody Cocktail for induction of arthritis in 48 hours | arthritomab.com Reviews
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ArthritoMab Antibody Cocktail for the induction of a shorter, more synchronized alternative to the collagen-induced arthritis (CIA) model.
arthritomab.com
Versatility of Strains in the Collagen Antibody Induced Arthritis Model
http://www.arthritomab.com/strains.html
Versatility of Collagen Antibody Induced Arthritis (CAIA). Unlike the Collagen-Induced Arthritis (CIA) model which requires a restricted MHC haplotype thereby limiting the available strains, the CAIA model using ArthritoMab™ Antibody Cocktail can be used in various strains including CIA-resistant, gene-knockouts and transgenic animals. Commonly used strains in the CAIA model:.
ArthritoMab Antibody Cocktail for induction of arthritis in 48 hours
http://www.arthritomab.com/index.html
ArthritoMab™ Antibody Cocktail - Induce disease in 48 hours. For many years, the Collagen Induced Arthritis (CIA) model has been the traditional model used for evaluating compounds in a model of Rheumatoid Arthritis. The model however, presents many challenges to scientists, which led the search for an alternative model using a cocktail of collagen II antibodies - the Collagen Antibody Induced Arthritis Model (CAIA or ACAIA). Challenges with the CIA model:. Disease Incidence and Severity.
Importance of Epitope Specificity in the Collagen Antibody Induced Arthritis Model
http://www.arthritomab.com/epitopes.html
In Collagen Induced Arthritis (CIA), the disease is mediated by autoantibodies which bind to collagen type II (CII) and complement. The epitope specificity is critically important to their pathogenicity. Eptiopes that are positively associated with arthritis are C1, J1 and U1 epitopes, which are spread across the entire CII region. ArthritoMab™ Antibody Cocktail:.
Advantages of the CAIA model using ArthritoMab Antibody Cocktail
http://www.arthritomab.com/advantages.html
Advantages of Collagen Antibody Induced Arthritis (CAIA) using ArthritoMab™ Antibody Cocktail. Benefits of the CAIA model:. The model is induced by administration of cocktail followed by an LPS boost. Disease symptoms are apparent within 24-48 hours with results obtained in as little as 10 days allowing the rapid progression of studies. The shortened study length reduces the facility requirements, administration periods and the amount of expensive compound and controls.
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Thursday, June 14, 2012. Thanks for stopping by! I'm so excited to have a post of mine featured on Kelly the Kitchen Kop. It's funny to me that something as clean and pure as raw milk from healthy, grass-fed cows is creating such a raucous - yet here we are. I'm grateful that my family still has access to this important part of our diet (which also means fresh, raw cream for my iced coffee, and cultured sour cream for our tacos - yum! Links to this post. Sunday, July 24, 2011. I don't bother with ferment...
ArthritoMab Antibody Cocktail for induction of arthritis in 48 hours
ArthritoMab™ Antibody Cocktail - Induce disease in 48 hours. For many years, the Collagen Induced Arthritis (CIA) model has been the traditional model used for evaluating compounds in a model of Rheumatoid Arthritis. The model however, presents many challenges to scientists, which led the search for an alternative model using a cocktail of collagen II antibodies - the Collagen Antibody Induced Arthritis Model (CAIA or ACAIA). Challenges with the CIA model:. Disease Incidence and Severity.
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