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ATDBio - Oligo synthesis experts - high quality modified oligos and fluorescent probes

Experts in oligo synthesis, specializing in high quality modified oligos, fluorescent probes, long oligos and large-scale oligonucleotide synthesis, for research and diagnostic kits.

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ATDBio - Oligo synthesis experts - high quality modified oligos and fluorescent probes | atdbio.com Reviews
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Experts in oligo synthesis, specializing in high quality modified oligos, fluorescent probes, long oligos and large-scale oligonucleotide synthesis, for research and diagnostic kits.
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1 oligo synthesis
2 custom oligonucleotides
3 research
4 and development
5 about us
6 who we are
7 book
8 on nucleic acids
9 oligo calculator
10 oligonucleotide properties
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ATDBio - Oligo synthesis experts - high quality modified oligos and fluorescent probes | atdbio.com Reviews

https://atdbio.com

Experts in oligo synthesis, specializing in high quality modified oligos, fluorescent probes, long oligos and large-scale oligonucleotide synthesis, for research and diagnostic kits.

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atdbio.com atdbio.com
1

Purification of oligonucleotides

http://www.atdbio.com/content/7/Purification-of-oligonucleotides

Call us: 44 (0)23 80596778 /. Request a quote online. 3 High-performance liquid chromatography (HPLC). 33 Which type of HPLC should be used to purify oligos? 34 Trityl-on (DMT-on) purification. 4 Fluorous affinity chromatography. 5 Polyacrylamide gel electrophoresis (PAGE). 6 Secondary structure in oligonucleotides. 7 Recommended methods of purification for different applications. Gel filtration also removes salts from oligonucleotides that have been purified by HPLC. Schematic representation of gel filt...

2

Synthesis and applications of chemically modified oligonucleotides

http://www.atdbio.com/content/19/Synthesis-and-applications-of-chemically-modified-oligonucleotides

Call us: 44 (0)23 80596778 /. Request a quote online. Synthesis and applications of chemically modified oligonucleotides. 1 Introduction to oligonucleotide labelling. 2 Components of a label. 3 Methods of oligonucleotide labelling. 4 The 5'-phosphate monomer and gene synthesis. 42 Preparation of 5'-phosphate oligonucleotides. 5 The 3'-phosphate group as a PCR blocker. 6 Biotinylated oligonucleotides and affinity capture. 7 5'-Aminohexyl oligonucleotides and post-synthetic labelling. P-ATP and T4 polynucl...

3

Nucleic acid-drug interactions

http://www.atdbio.com/content/16/Nucleic-acid-drug-interactions

Call us: 44 (0)23 80596778 /. Request a quote online. 21 Distamycin and netropsin. 5 DNA cleavage agents. 52 Enediyne antitumour antibiotics. 522 Esperamicins and calichemicins. Nucleic acids play an important role in cellular processes including cell division ( DNA replication. And protein synthesis ( transcription. These processes occur both in healthy cells, and in cancer cells, in which case they are targets for anti-cancer drugs. That sit in the minor groove;. That sandwich between base pairs;.

4

Nucleic acid structure

http://www.atdbio.com/content/5/Nucleic-acid-structure

Call us: 44 (0)23 80596778 /. Request a quote online. 1 2'-Deoxyribonucleic acid (DNA). 2 Ribonucleic acid (RNA). 4 Nucleic acid duplexes. 5 Techniques for determining nucleic acid structure. 51 Nuclear magnetic resonance (NMR). 52 Crystallization and X-ray diffraction. 2′-Deoxyribonucleic acid (DNA). DNA (2′-deoxyribonucleic acid) is the molecular store of genetic information in nearly all living systems. It is a large polymeric molecule composed of monomers known as. As a free sugar it can. The phospha...

5

Nucleic Acids Book - Chemistry and Biology of Nucleic Acids

http://www.atdbio.com/nucleic-acids-book

Call us: 44 (0)23 80596778 /. Request a quote online. A free online book on the chemistry and biology of nucleic acids, written by Prof. Tom Brown and Dr Tom Brown (Jr). The book is ideal for chemistry and biology students and also provides practical information for researchers working in the lab. Transcription, Translation and Replication. Mutagenesis and DNA repair. Synthesis and applications of chemically modified oligonucleotides. Synthesis and properties of fluorescent oligonucleotides.

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browngroupnucleicacidsresearch.org.uk browngroupnucleicacidsresearch.org.uk

Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation

http://www.browngroupnucleicacidsresearch.org.uk/papers/view/329/Molecular-Requirements-of-High-Fidelity-Replication-Competent-DNA-Backbones-for-Orthogonal-Chemical-Ligation

Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation. A Shivalingam, A. E. S. Tyburn, A. H. El-Sagheer and T. Brown. J Am Chem. Soc. Graphene Oxide-Upconversion Nanoparticle Based Optical Sensors for Targeted Detection of mRNA Biomarkers Present in Alzheimer’s Disease and Prostate Cancer. Dec 27th, 2016. P Vilela, A. H. El-Sagheer, T. M. Millar, T. Brown, O. L. Muskens and A. G. Kanaras. Professor of Nucleic Acid Chemistry.

browngroupnucleicacidsresearch.org.uk browngroupnucleicacidsresearch.org.uk

Tom Brown Group - Papers

http://www.browngroupnucleicacidsresearch.org.uk/papers

Showing 1 to 20. Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation. A Shivalingam, A. E. S. Tyburn, A. H. El-Sagheer and T. Brown. J Am Chem. Soc. Graphene Oxide-Upconversion Nanoparticle Based Optical Sensors for Targeted Detection of mRNA Biomarkers Present in Alzheimer’s Disease and Prostate Cancer. P Vilela, A. H. El-Sagheer, T. M. Millar, T. Brown, O. L. Muskens and A. G. Kanaras. Angew Chem. Int. Ed. J Am Chem. Soc. H O Abdallah, Y. P&#...

clickgene.eu clickgene.eu

Partners | ClickGene

http://www.clickgene.eu/partners

Skip to main content. Academic and Industry Partners. Dublin City University (DCU). School of Chemical Sciences. Ludwig-Maximilian University Munich (LMUM). Faculty for Chemistry and Pharmacy. LMU’s Department of Chemistry is best known for:. 1) World leading expertise on the synthesis and modification of nucleic acids, including the biochemical manipulation of nucleic acids. Extensive links with cell biologist. Oxford, United Kingdom. National Center for Scientific Research "Demokritos" (NCSRD). Also kn...

lpmhealthcare.com lpmhealthcare.com

Lpmhealthcare » OLIGO 2016 OXFORD

http://lpmhealthcare.com/oligo-2016-oxford

8212; Main Menu —. 2016 & 2017. NGS 2016 Oxford – 12 July. Venoms 2016 – 05-06 Sept. Phages 2016 – 07-08 Sept. Emerging Viruses 2016 – 12 Sept. Influenza 2016 – 13-15 Sept. Genome Editing 2017 – 4 April. Exosomes 2017 – 06 April. OLIGO 2017 OXFORD – 10 April. Aptamers 2017 – 11-12 April. 2015 & 2016. Exosomes 2016 Oxford – 04 April. RNAi 2016 – 05 April. Aptamers 2016 – 04-05 April. OLIGO 2016 Oxford – 06 April. Genome Editing & Gene Modulation 2016 – 06-08 April. IST 2015 Oxford – 25-30 Sept. Respirator...

libpubmedia.co.uk libpubmedia.co.uk

Library Publishing Media » Aptamers 2016

http://libpubmedia.co.uk/aptamers-2016

Journal of Venom Research. Pseudotype – coming soon. Aptamers – coming soon. The British Journal of Extracellular Vesicles (BJEV). Start a New Journal. Our Events – Forthcoming. Aptamers 2017 – 11-12 April. OLIGO 2017 Oxford – 10 April. 3rd Oxford Symposium on Aptamers. St Hilda's College, Oxford, UK. Co-hosted with our 2nd Therapeutic and Antisense Oligonucleotides Symposium, Oligo 2016. On 06 April at St Hilda's College, Oxford, UK. 3rd Oxford Symposium on Aptamers. St Hilda's College, Oxford, UK.

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Sponsors - fb3

http://fb3.cloud.ucsd.edu/home/sponsors

Http:/ www.trilinkbiotech.com/send/brewerytour.html. La Jolla and San Diego. We are grateful to the following sponsors:.

browngroupnucleicacidsresearch.org.uk browngroupnucleicacidsresearch.org.uk

Tom Brown Group - Photos

http://www.browngroupnucleicacidsresearch.org.uk/photos

See all our photos on our Flickr page. Professor of Nucleic Acid Chemistry. E-mail: tom.@chem.ox.ac.uk. We are always looking for enthusiastic, hard-working people. If you are interested, please contact us.

browngroupnucleicacidsresearch.org.uk browngroupnucleicacidsresearch.org.uk

Tom Brown Group - News

http://www.browngroupnucleicacidsresearch.org.uk/news

New amide bond ligation method described in JACS. Jan 18th, 14:51. Arun Shivalingam, Agnes Tyburn and Afaf El-Sagheer’s paper. Molecular Requirements of High-Fidelity Replication-Competent DNA. Backbones for Orthogonal Chemical Ligation. Which describes an exciting new amide bond ligation method for DNA. That is chemically orthogonal to CuAAC click ligation, has been published online in. J Amer. Chem. Soc. Prof Tom Brown wins BBSRC Innovator of the Year 2016. May 18th 2016, 17:55. May 12th 2016, 22:24.

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ATDBio - Oligo synthesis experts - high quality modified oligos and fluorescent probes

Call us: 44 (0)23 80596778 /. Request a quote online. Experts in oligonucleotide synthesis. We are experts in nucleic acids chemistry. Collectively, we have over 50 years' experience in nucleic acids chemistry and oligo synthesis, and we are at the forefront of nucleic acids research. A unique combination of knowledge, experience and intimacy with our customers gives ATDBio a decisive edge. We provide unrivalled technical support and expertise. We help you make your experiments work. Please get in touch.

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