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The Baum Group studies protein-protein interaction and protein aggregation through biochemical and biophysical techniques, including Nuclear Magnetic Resonance.

http://baum.rutgers.edu/

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Home | The Baum Group | baum.rutgers.edu Reviews

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The Baum Group studies protein-protein interaction and protein aggregation through biochemical and biophysical techniques, including Nuclear Magnetic Resonance.

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Protein Aggregation | The Baum Group

http://baum.rutgers.edu/protein-aggregation

Α-synuclein aggregation and oxidative stress. Very recently, it has been shown that in vivo. How do the in vivo. Acetylation influences α-synuclein aggregation? What are the timescales of the fluctuations and the extent of residual secondary structure in the different species and how do these relate to the rate of fibril formation? Does oxidative stress increases α-synuclein aggregation? Α-synuclein homologs and interactions.

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Group Members | The Baum Group

http://baum.rutgers.edu/group-members

Principle Investigator and the Director of the Nuclear Magnetic Resonance Facilities. Jeanbaum at rutgers.edu. Dr Ana Monica Nunes. Amnunes at rci.rutgers.edu. Codyhoop at rutgers.edu. Structural and functional effects of pathological collagen mutations. Gmoriar at rci.rutgers.edu. Understand how covalent modifications and ligands, relevant to oxidative stress, affect the aggregation pathway of alpha-synuclein in disease. Jiezhu.jz at rutgers.edu. Mpolson at scarletmail.rutgers.edu.

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Collagen-Protein Interaction | The Baum Group

http://baum.rutgers.edu/collagen-protein-interaction

The binding of integrins to collagen plays a critical role in numerous cellular adhesion processes including platelet activation and aggregation, a key process in clot formation, and cancer metastasis. The two major integrin receptors, α1β1 and α2β1, bind collagen through their α1 and α2 I-domain. The binding is specific with variable affinities, depending on the collagen sequence as well as the integrin protein. Our research focuses on addressing the following questions:.

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Publications | The Baum Group

http://baum.rutgers.edu/publications

Janowska, M.K. and J. Baum. Intermolecular Paramagnetic Relaxation Enhancement (PRE) Studies of Transient Complexes in Intrinsically Disordered Proteins , Methods Mol. Biol. Janowska, M.K. and J. Baum. "The loss of inhibitory C-terminal conformations in disease associated P123Hβ-synuclein", Protein Sci. Fu, I, D.A. Case and J. Baum. "Dynamic water-mediated hydrogen bonding in a collagen model peptide", Biochemistry. Moriarty, G.M., M.K. Janowska, L. Kang, and J. Baum. Explorin...8), 1128-38 (2013). Kang,...

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Proteomics Faculty | Proteomics Public

http://public.proteomics.rutgers.edu/faculty

Skip to main content. Chemistry and Chemical Biology. Helen M. Berman. Board of Governors Professor Chemistry and Chemical Biology;. Director Emerita, RCSB Protein Data Bank;. Founding Director, Center for Integrative Proteomics Research. Stephen K. Burley. Director, Center for Integrative Proteomics Research;. Director, RCSB Protein Data Bank;. Founding Director, Institute for Quantitative Biomedicine at Rutgers;. Distinguished Professor, Chemistry and Chemical Biology;. Chemistry and Chemical Biology.

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The Baum Group studies protein-protein interaction and protein aggregation through biochemical and biophysical techniques, including Nuclear Magnetic Resonance.

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