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BetaBlue, Inc. is a developmental stage biopharmaceutical company that is developing novel small molecule therapeutics that exhibit functional selectivity at clinically relevant dopamine receptors to treat neurological illness. The Company has lead compounds with a unique pharmacological signature that have shown activity as potentially novel antipsychotics in models of schizophrenia. Ligands to Facilitate Biased Signaling. BetaBlue has strong ties with the University of North Carolina where initial inte...

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BetaBlue, Inc. is a developmental stage biopharmaceutical company that is developing novel small molecule therapeutics that exhibit functional selectivity at clinically relevant dopamine receptors to treat neurological illness. The Company has lead compounds with a unique pharmacological signature that have shown activity as potentially novel antipsychotics in models of schizophrenia. Ligands to Facilitate Biased Signaling. BetaBlue has strong ties with the University of North Carolina where initial inte...
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BetaBlue home page | beta-blue.com Reviews

https://beta-blue.com

BetaBlue, Inc. is a developmental stage biopharmaceutical company that is developing novel small molecule therapeutics that exhibit functional selectivity at clinically relevant dopamine receptors to treat neurological illness. The Company has lead compounds with a unique pharmacological signature that have shown activity as potentially novel antipsychotics in models of schizophrenia. Ligands to Facilitate Biased Signaling. BetaBlue has strong ties with the University of North Carolina where initial inte...

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1

BetaBlue:publications

http://www.beta-blue.com/publications.html

2015 Dopamine Receptors-IUPHAR Review 13. British J of Pharmacology. Mailman RB and Murthy V 2010. Third Generation Antipsychotic Drugs: Partial Agonism or Receptor Functional Selectivity? 2017 New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy. Biological Psychiatry. 2016 Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proc Natl Acad Sci USA.

2

BetaBlue:management_team

http://www.beta-blue.com/management.html

Jeremy D. Ollerenshaw, PhD. Dr Ollerenshaw is Co-Founder and Chief Executive Officer at BetaBlue, Inc. He has a PhD from the University of Leicester in the UK and has worked in various R&D leadership capacities in the pharmaceutical and medical device industries for over 23 years. He has played an integral part in drug and medical device regulatory filings internationally and has published more than 60 scientific research articles as book chapters and in medical and scientific journals. Dr Montgomery has...

3

BetaBlue:pipeline

http://www.beta-blue.com/BetaBlue_Pipeline.html

Addiction / Movement Disorders. BetaBlue's lead compounds, BBL1010 and BBL1020 are structurally based upon the backbone of the aripiprazole molecule and have functional bias and site-specific selectivity at dopamine D. This functional selectivity profile, coupled with demonstrated favorable pharmacokinetic properties in vivo. Suggests that these compounds may yield distinct advantages as candidate pharmaceuticals in the treatment of a number of dopamine D.

4

BetaBlue:investors

http://www.beta-blue.com/investors.html

BetaBlue News and Presentations. January 26, 2017:. BetaBlue is Selected to Present at the 2017 CED Life Science Conference. February 22, 2017:. CED Life Science presenter profile: BetaBlue.

5

BetaBlue home page

http://www.beta-blue.com/index.html

BetaBlue, Inc. is a developmental stage biopharmaceutical company that is developing novel small molecule therapeutics that exhibit functional selectivity at clinically relevant dopamine receptors to treat neurological illness. The Company has lead compounds with a unique pharmacological signature that have shown activity as potentially novel antipsychotics in models of schizophrenia. Ligands to Facilitate Biased Signaling. BetaBlue has strong ties with the University of North Carolina where initial inte...

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BetaBlue, Inc. is a developmental stage biopharmaceutical company that is developing novel small molecule therapeutics that exhibit functional selectivity at clinically relevant dopamine receptors to treat neurological illness. The Company has lead compounds with a unique pharmacological signature that have shown activity as potentially novel antipsychotics in models of schizophrenia. Ligands to Facilitate Biased Signaling. BetaBlue has strong ties with the University of North Carolina where initial inte...

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