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Bioexigence -in vitro and ex vivo test laboratory - Human cell cultures - Services for pharmaceutical industries- Services for cosmetic industries- Services for active ingredienrs manufacturers - Besançon -France- Franche-Comté

Bioexigence develops models in order to address and support new and innovative claims of its customers. Classic evaluation tests are performed on skin cells lines (with *** and specific age) or skin explants maintained in survival conditions. Recently, thanks to a device GlasBoxPlus  developed by Pr Philippe Humbert, Head of the Department of Dermatology of Besançon (France), Bioexigence is able to compare several actives in order to find lifting effects, anti-wrinkle effects, anti-stretch marks effe

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Bioexigence -in vitro and ex vivo test laboratory - Human cell cultures - Services for pharmaceutical industries- Services for cosmetic industries- Services for active ingredienrs manufacturers - Besançon -France- Franche-Comté | bioexigence.com Reviews
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Bioexigence develops models in order to address and support new and innovative claims of its customers. Classic evaluation tests are performed on skin cells lines (with *** and specific age) or skin explants maintained in survival conditions. Recently, thanks to a device GlasBoxPlus  developed by Pr Philippe Humbert, Head of the Department of Dermatology of Besançon (France), Bioexigence is able to compare several actives in order to find lifting effects, anti-wrinkle effects, anti-stretch marks effe
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1 in vitro tests
2 ex vivo tests
3 skin
4 apoptosis
5 Franz cells
6 wound healing
7 in vitro models
8 ex vivo models
9 skin explant
10 3D culture
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présentation,accueil,équipe,convention,localisation,nos locaux,accès,actualités,secteurs d'activité,lignées cellulaires,vieillissement photo induit,mélanogénèse,derme infecté,immunohistochimie,partenariat,r and d,téléchargements
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Bioexigence -in vitro and ex vivo test laboratory - Human cell cultures - Services for pharmaceutical industries- Services for cosmetic industries- Services for active ingredienrs manufacturers - Besançon -France- Franche-Comté | bioexigence.com Reviews

https://bioexigence.com

Bioexigence develops models in order to address and support new and innovative claims of its customers. Classic evaluation tests are performed on skin cells lines (with *** and specific age) or skin explants maintained in survival conditions. Recently, thanks to a device GlasBoxPlus  developed by Pr Philippe Humbert, Head of the Department of Dermatology of Besançon (France), Bioexigence is able to compare several actives in order to find lifting effects, anti-wrinkle effects, anti-stretch marks effe

SUBDOMAINS

en.bioexigence.com en.bioexigence.com

Bioexigence - Culture of human cells - Services for pharmaceutical and cosmetic laboratories - Besançon - Franche-Comté

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. A leg ulcer that does not heal, the appearance of wrinkles or stretch marks . Thanks to BIOEXIGENCE, which offers services including in vitro tests on cell cultures and ex vivo tests on operative wastes, BIOEXIGENCE is able to provide proofs of efficacy of a medicine or cosmetic actives. Bioexigence - 8 r Alfred de Vigny - 25000 BESANCON - Tel : 33 (0)3 81 51 48 98 - Fax : 33 (0) 03 81 51 32 29 mentions légales.

INTERNAL PAGES

bioexigence.com bioexigence.com
1

Derme équivalent infecté par des bactéries | Bioexigence (Besançon - Franche Comte)

http://www.bioexigence.com/page-derme-infecte,14.html

Modèles in vitro et modèles ex vivo. Flexercell : Etude des contraintes mécaniques sur le métabolisme cellulaire. GlasBoxPlus système : screening de molécules anti-ride, lifting, protecteur solaire et anti-vergeture. Modèle in vitro de "cicatrisation" et de "régénérateur cellulaire". Screening de formulations ou actifs anti-cellulite. Etude de pénétration cutanée sur peau totale. Evaluation d'un effet anti-allergique. Quantification des SBC (Sun burn cells), de la mélanine, Test des comètes sur biopsies.

2

Nos locaux | Bioexigence (Besançon - Franche Comte)

http://www.bioexigence.com/page-nos-locaux,7.html

Modèles in vitro et modèles ex vivo. Flexercell : Etude des contraintes mécaniques sur le métabolisme cellulaire. GlasBoxPlus système : screening de molécules anti-ride, lifting, protecteur solaire et anti-vergeture. Modèle in vitro de "cicatrisation" et de "régénérateur cellulaire". Screening de formulations ou actifs anti-cellulite. Etude de pénétration cutanée sur peau totale. Evaluation d'un effet anti-allergique. Quantification des SBC (Sun burn cells), de la mélanine, Test des comètes sur biopsies.

3

Mélanogénèse | Bioexigence (Besançon - Franche Comte)

http://www.bioexigence.com/page-melanogenese,17.html

Modèles in vitro et modèles ex vivo. Flexercell : Etude des contraintes mécaniques sur le métabolisme cellulaire. GlasBoxPlus système : screening de molécules anti-ride, lifting, protecteur solaire et anti-vergeture. Modèle in vitro de "cicatrisation" et de "régénérateur cellulaire". Screening de formulations ou actifs anti-cellulite. Etude de pénétration cutanée sur peau totale. Evaluation d'un effet anti-allergique. Quantification des SBC (Sun burn cells), de la mélanine, Test des comètes sur biopsies.

4

Services de haut niveau technologique aux laboratoires pharmaceutiques et cosmétiques | Bioexigence (Besançon - Franche Comte)

http://www.bioexigence.com/page-secteurs-d-activite,9.html

Modèles in vitro et modèles ex vivo. Flexercell : Etude des contraintes mécaniques sur le métabolisme cellulaire. GlasBoxPlus système : screening de molécules anti-ride, lifting, protecteur solaire et anti-vergeture. Modèle in vitro de "cicatrisation" et de "régénérateur cellulaire". Screening de formulations ou actifs anti-cellulite. Etude de pénétration cutanée sur peau totale. Evaluation d'un effet anti-allergique. Quantification des SBC (Sun burn cells), de la mélanine, Test des comètes sur biopsies.

5

Test de cicatrisation et régénération cellulaire de la peau | Bioexigence (Besançon - Franche Comte)

http://www.bioexigence.com/page-monocouches-de-fibroblastes-et-de-keratinocytes-blesses-et-derme-blesse,13.html

Modèles in vitro et modèles ex vivo. Flexercell : Etude des contraintes mécaniques sur le métabolisme cellulaire. GlasBoxPlus système : screening de molécules anti-ride, lifting, protecteur solaire et anti-vergeture. Modèle in vitro de "cicatrisation" et de "régénérateur cellulaire". Screening de formulations ou actifs anti-cellulite. Etude de pénétration cutanée sur peau totale. Evaluation d'un effet anti-allergique. Quantification des SBC (Sun burn cells), de la mélanine, Test des comètes sur biopsies.

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LINKS TO THIS WEBSITE

en.bioexigence.com en.bioexigence.com

Dowload room | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-dowload-room,20.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Bioexigence - 8 r Alfred de Vigny - 25000 BESANCON - Tel : 33 (0)3 81 51 48 98 - Fax : 33 (0) 03 81 51 32 29 mentions légales.

en.bioexigence.com en.bioexigence.com

Test verification effectiveness of active ingredients on skin cell lines | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-cell-lines,11.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Bioexigence can test the efficiency of your actives on several monolayer cutaneous healthy and pathological cell cultures. Monolayer cell cultures make it possible to test:. Cell viability and proliferation. Expression of cytoskeleton proteins (F-Actin). Synthesis of ECM components (collagen, elastin, proteoglycans.). Healthy cells obtained after extraction. Culture of skin fragment. Les keratinocytes are obtained after sep...

en.bioexigence.com en.bioexigence.com

Offices | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-offices,7.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Bioexigence - 8 r Alfred de Vigny - 25000 BESANCON - Tel : 33 (0)3 81 51 48 98 - Fax : 33 (0) 03 81 51 32 29 mentions légales.

en.bioexigence.com en.bioexigence.com

Services of high technological level for pharmaceutical and cosmetics | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-our-customers,9.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Evaluation of efficacy of actives or wound dressings. Demonstration of lifting effects, anti-wrinkle effects, effects on stretch marks , sun protection or depigmenting cream. Dermatological research, Food Industry, Chemical Industry. Bioexigence - 8 r Alfred de Vigny - 25000 BESANCON - Tel : 33 (0)3 81 51 48 98 - Fax : 33 (0) 03 81 51 32 29 mentions légales.

en.bioexigence.com en.bioexigence.com

Current news | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/actualites.php

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. BIOEXIGENCE at In Cosmetics, Barcelona, Spain, 14-16 april 2015. BIOEXIGENCE will be pleased to welcome you on stand n° 6R35 Test in In Cosmetics, Barcelona, Spain, 14-16 April 2015. Use of a model of a blood-induced bruise for the evaluation of formulations on bruising. New scientific publication :Mecanostimulation of the skin.

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Local partnerships - CERT - Centre d'études et de recherche sur le tégument

http://www.cert-besancon.com/en/2012-08-24-14-25-43/local-partnerships.html

Your contacts in CERT. Centre Hospitalier et Universitaire de Besançon :. Hôpitaux Saint-Jacques et Jean Minjoz, service de Dermatologie. Unité du service de Dermatologie: Centre de Traitement Ambulatoire des Plaies Chroniques ( CTAPC. Hôpital Jean Minjoz, service de Traumatologie. Clinique Saint Vincent à Besançon. Université de Franche-Comté, faculté de médecine et de pharmacie :. Laboratoire d’ingénierie et Biologie Cutanées (LIBC). Centre de Diagnostic du vieillissement de la peau ( CDVP.

en.bioexigence.com en.bioexigence.com

Melanogenesis | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-melanogenesis,17.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Your active is a skin-lightening agent or melanogenic stimulator, test its activity on melanocyte lines. Studies of melanogenesis by :. Quantification of total melanin. Evaluation of the activity of tyrosinase. Bioexigence - 8 r Alfred de Vigny - 25000 BESANCON - Tel : 33 (0)3 81 51 48 98 - Fax : 33 (0) 03 81 51 32 29 mentions légales.

en.bioexigence.com en.bioexigence.com

R & D | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-r-d,19.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Bioexigence performs innovative cell models in order to show the efficiency of your actives. Bioexigence is specialized in the fields of:. Photoaging model allowing the measurment of the lifting effect of actives. Infected dermal equivalent by bacteria. Injured keratinocyte or fibroblast monolayers in order to show the cell regeneration. Pharmacokinetic studies thanks to ex vivo cutaneous microdialysis.

en.bioexigence.com en.bioexigence.com

Dermis equivalent infected by bacteria | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-infected-dermal-equivalent,14.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Infected tense dermal equivalent by bacteria. In hospital, bacteria infections are responsible for delayed healing of wounds such as leg ulcers. Our model makes it possible to know whether the use of an antibacterial dressing does not disturb the fibroblast viability and their differentiation into myofibroblast, the key element of the healing. Journal des plaies et. Déc 2005, IX (51) : 33-37.

en.bioexigence.com en.bioexigence.com

Immunohistochemistry | Bioexigence (Besançon - Franche Comte)

http://en.bioexigence.com/page-immunohistochemistry,18.html

Dermal equivalent and GlasBoxPlus. Wounded dermal equivalent and monolayer cells. Bioexigence - 8 r Alfred de Vigny - 25000 BESANCON - Tel : 33 (0)3 81 51 48 98 - Fax : 33 (0) 03 81 51 32 29 mentions légales.

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Bioexigence -in vitro and ex vivo test laboratory - Human cell cultures - Services for pharmaceutical industries- Services for cosmetic industries- Services for active ingredienrs manufacturers - Besançon -France- Franche-Comté

Modèles in vitro et modèles ex vivo. Flexercell : Etude des contraintes mécaniques sur le métabolisme cellulaire. GlasBoxPlus système : screening de molécules anti-ride, lifting, protecteur solaire et anti-vergeture. Modèle in vitro de "cicatrisation" et de "régénérateur cellulaire". Screening de formulations ou actifs anti-cellulite. Etude de pénétration cutanée sur peau totale. Evaluation d'un effet anti-allergique. Quantification des SBC (Sun burn cells), de la mélanine, Test des comètes sur biopsies.

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