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BioKin, Ltd. - Software and Consulting for the life sciences: Home page

Welcome to BioKin, home of the DynaFit. Software package and a source of scientific information regarding biochemical and biophysical kinetics and equilibria. 11/29/2016] The DynaFit Scripting Manual. Was updated in sections discussing the NL2SOL least-squares minimization algorithm. Journal article in print. 11/05/2016] Page-proof corrections to ****. Biochem. Manuscript No. ABIO-16-714R1. BioKin Technical Note TN-2016-03. BioKin Technical Note TN-2016-02. BioKin Technical Note TN-2016-01.

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Welcome to BioKin, home of the DynaFit. Software package and a source of scientific information regarding biochemical and biophysical kinetics and equilibria. 11/29/2016] The DynaFit Scripting Manual. Was updated in sections discussing the NL2SOL least-squares minimization algorithm. Journal article in print. 11/05/2016] Page-proof corrections to ****. Biochem. Manuscript No. ABIO-16-714R1. BioKin Technical Note TN-2016-03. BioKin Technical Note TN-2016-02. BioKin Technical Note TN-2016-01.
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BioKin, Ltd. - Software and Consulting for the life sciences: Home page | biokin.com Reviews

https://biokin.com

Welcome to BioKin, home of the DynaFit. Software package and a source of scientific information regarding biochemical and biophysical kinetics and equilibria. 11/29/2016] The DynaFit Scripting Manual. Was updated in sections discussing the NL2SOL least-squares minimization algorithm. Journal article in print. 11/05/2016] Page-proof corrections to ****. Biochem. Manuscript No. ABIO-16-714R1. BioKin Technical Note TN-2016-03. BioKin Technical Note TN-2016-02. BioKin Technical Note TN-2016-01.

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ftp.biokin.com ftp.biokin.com

BioKin, Ltd. - Software and Consulting for the life sciences: Home page

Welcome to BioKin, home of the DynaFit. Software package and a source of scientific information regarding biochemical and biophysical kinetics and equilibria. 11/29/2016] The DynaFit Scripting Manual. Was updated in sections discussing the NL2SOL least-squares minimization algorithm. Journal article in print. 11/05/2016] Page-proof corrections to Anal. Biochem. Manuscript No. ABIO-16-714R1. BioKin Technical Note TN-2016-03. BioKin Technical Note TN-2016-02. BioKin Technical Note TN-2016-01.

INTERNAL PAGES

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1

Statistical Tools

http://www.biokin.com/tools/index.html

Basic tools for statistical data analysis: standard deviation, F-statistics, and more. Optimal Design for Inhibitor Screening. Statistical D-Optimal design (Box-Lucas method) for the optimal choice of enzyme inhibitors in a screening project. Automatic derivation of steady-state rate equations. Derive steady-state enzymatic rate equations from a symbolic input, under the steady-state approximation (in the absence of tight bindign). Tools for basic statistical analysis of experimental data.

2

BioKin, Ltd. - Software and Consulting for the life sciences: Home page

http://www.biokin.com/index.html

Welcome to BioKin, home of the DynaFit. Software package and a source of scientific information regarding biochemical and biophysical kinetics and equilibria. BioKin Technical Note TN-2015-06. 11/23/2015] Time-dependent inhibition of 5alpha-steroid reductase. BioKin Technical Note TN-2015-05. 11/16/2015] Determination of substrate kinetic parameters from progress curve data. 11/16/2015] Software DynaFit was updated to version 4.07.066. BioKin Technical Note TN-2015-04. BioKin Technical Note TN-2015-03.

3

DynaFit - (Bio)Chemical Kinetics and Equilibria

http://www.biokin.com/dynafit/index.html

Analysis of (bio)chemical kinetics and equilibria. The main purpose of the program DynaFit is to perform nonlinear least-squares regression of chemical kinetic, enzyme kinetic, or ligand-receptor binding data. The experimental data can be either initial reaction velocities in dependence on the concentration of varied species (e.g., inhibitor concentration vs. velocity), or the reaction progress curves (e.g., time vs. absorbance). Enzyme : k1 k2 Enzyme Inhibitor. Complex : k3 k4 Enzyme Substrate.

4

BioKin, Ltd. - Software and Consulting for the life sciences: About us

http://www.biokin.com/about.html

Essential facts about BioKin Ltd. Petr Kuzmic, Ph.D. Essential facts about BioKin Ltd. United States Corporation since November 1991. US Tax Code Principal Business Activity: 541600. Management, scientific, and technical consulting. Initially (1991) incorporated in the state of Wisconsin. Currently (as of 2008) incorporated in the state of Delaware. Currently (as of 2008) operating in the state of Massachusetts ( contact. Owner and President: Dr. Petr Kuzmic. New Clients: IRS Form "W-9". We design custom...

5

BioKin, Ltd. - Journal articles and technical reports

http://www.biokin.com/publications/index.html

Journal articles and technical reports. Dr Petr Kuzmic, owner of BioKin Ltd., has published more than 60 articles. And book chapters in peer reviewed journals and monographs. According to the Web of Science. Database, these journal articles have been cited 2,028 times. As of April 7, 2014. The most highly cited single journal article. Is the initial description of DynaFit. An abbreviated list of journal publications is shown here. Including selected full text articles in PDF format.

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LINKS TO THIS WEBSITE

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BioKin, Ltd. - Consulting Services

http://ftp.biokin.com/consulting/index.html

Data analysis in chemistry, biology, biochemistry, and related fields. BioKin Ltd. provides consulting services and custom software design for pharmaceutical research laboratories. Typically (but not necessarily) the product of each consulting agreement is a highly specialized software program derived from the program DYNAFIT [P. Kuzmic (1996) Anal. Biochem. 260-273]. Each specialized program is:. Conforms to the nature of the biochemical target (kinetic mechanism of inhibition). In these simple cases of...

ftp.biokin.com ftp.biokin.com

Lecture Courses and Workshops

http://ftp.biokin.com/courses/index.html

Lecture Courses and Workshops. Dr Kuzmic, the proprietor of BioKin Ltd., teaches courses in modern methods of biochemical and biophysical data analysis. Determination of Binding Constants and Mechanisms 2014. Determinatinon of Binding Constants and Mechanisms. May 2, 2014. Biochemical Society, London, UK, Darwin House. Intensive workshop for practicing biologists and biochemists at the graduate or post-graduate level. One day, total six hours of programming. May 12-16, 2014. Mon Dec 7 17:35:03 2015.

jmhartsoftware.com jmhartsoftware.com

JMH Associates

http://www.jmhartsoftware.com/comments_updates.html

C#/NET vs Windows Native Code. Windows API vs. C Run-Time Library. Comments on the Windows API. Edition 4 and Edition 3 Errata and Comments. Version 1.16 April, 2015. Last Update - October 28, 2015 (newer entries in red). I'd like to express my appreciation to the many readers who have contributed to the information here, and I've cited them whereever possible. Thank you for your assistance and your patience; the contributions have been extremely helpful - JMH. October 28, 2015. Pages 3-5 (and elsewhere).

bio-temps.blogspot.com bio-temps.blogspot.com

Exemple en biologie: March 2006

http://bio-temps.blogspot.com/2006_03_01_archive.html

Friday, March 03, 2006. Le but de ce travail est de montrer qu'en prenant une base. Exponentielle de temps, on peut décrire mathématiquement. Une courbe expérimentale. Une méthode déduite d'une hypothèse sur le temps. Une application de cette méthode en biologie permet de. Décrire une réaction de la protease H.I.V.(1). Ma démarche est de démontrer la. Généralité de cette méthode dans diverses. Matériel et Méthode. Les résultats expérimentaux de la. Système naturellement stable. Y = k ( 1-e(-t/jo). D&eacu...

ftp.biokin.com ftp.biokin.com

Lectures and Seminars

http://ftp.biokin.com/lectures.html

A selection of invited talks given by Dr. Petr Kuzmic:. University of Massachusetts Medical School, April 2015. Brandeis University, December 2014. AstraZeneca, September 2014. Brandeis University, March 2014. Several most recent talks address the same topic, so there is significant overlap. However each presentation attempts to address the topic from a slightly different perspective. University of Massachusetts Medical School, April 2015. A New 'Microscopic' Look at Steady-state Enzyme Kinetics. Brandei...

ftp.biokin.com ftp.biokin.com

DynaFit - (Bio)Chemical Kinetics and Equilibria

http://ftp.biokin.com/dynafit/index.html

Analysis of (bio)chemical kinetics and equilibria. The main purpose of the program DynaFit is to perform nonlinear least-squares regression of chemical kinetic, enzyme kinetic, or ligand-receptor binding data. The experimental data can be either initial reaction velocities in dependence on the concentration of varied species (e.g., inhibitor concentration vs. velocity), or the reaction progress curves (e.g., time vs. absorbance). Enzyme : k1 k2 Enzyme Inhibitor. Complex : k3 k4 Enzyme Substrate.

ftp.biokin.com ftp.biokin.com

BioKin, Ltd. - Software and Consulting for the life sciences: Home page

http://ftp.biokin.com/index.html

Welcome to BioKin, home of the DynaFit. Software package and a source of scientific information regarding biochemical and biophysical kinetics and equilibria. BioKin Technical Note TN-2015-06. 11/23/2015] Time-dependent inhibition of 5alpha-steroid reductase. BioKin Technical Note TN-2015-05. 11/16/2015] Determination of substrate kinetic parameters from progress curve data. 11/16/2015] Software DynaFit was updated to version 4.07.066. BioKin Technical Note TN-2015-04. BioKin Technical Note TN-2015-03.

ftp.biokin.com ftp.biokin.com

BioKin, Ltd. - Software and Consulting for the life sciences: About us

http://ftp.biokin.com/about.html

Essential facts about BioKin Ltd. Petr Kuzmic, Ph.D. Essential facts about BioKin Ltd. United States Corporation since November 1991. US Tax Code Principal Business Activity: 541600. Management, scientific, and technical consulting. Initially (1991) incorporated in the state of Wisconsin. Currently (as of 2008) incorporated in the state of Delaware. Currently (as of 2008) operating in the state of Massachusetts ( contact. Owner and President: Dr. Petr Kuzmic. New Clients: IRS Form "W-9". We design custom...

ftp.biokin.com ftp.biokin.com

Statistical Tools

http://ftp.biokin.com/tools/index.html

Basic tools for statistical data analysis: standard deviation, F-statistics, and more. Optimal Design for Inhibitor Screening. Statistical D-Optimal design (Box-Lucas method) for the optimal choice of enzyme inhibitors in a screening project. Automatic derivation of steady-state rate equations. Derive steady-state enzymatic rate equations from a symbolic input, under the steady-state approximation (in the absence of tight bindign). Tools for basic statistical analysis of experimental data.

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Retrouvez le plaisir de bouger avec les physiothérapeutes de Biokin! Biokin vous offre des services de physiothérapie afin de vous permettre de vous débarrasser de vos douleurs et de régler vos problèmes de santé. Nos services représentent une solution durable à vos maux. Une équipe chevronnée. L’approche des professionnels de Biokin est orientée entièrement vers le patient. Nous prenons tout le temps nécessaire afin d’évaluer votre condition, pour bien compren...Nous croyons que personne ne devrait se r...

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BioKin, Ltd. - Software and Consulting for the life sciences: Home page

Welcome to BioKin, home of the DynaFit. Software package and a source of scientific information regarding biochemical and biophysical kinetics and equilibria. 11/29/2016] The DynaFit Scripting Manual. Was updated in sections discussing the NL2SOL least-squares minimization algorithm. Journal article in print. 11/05/2016] Page-proof corrections to Anal. Biochem. Manuscript No. ABIO-16-714R1. BioKin Technical Note TN-2016-03. BioKin Technical Note TN-2016-02. BioKin Technical Note TN-2016-01.

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