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BISC - Binary Interacting SubComplexes

Thomas Juettemann and Dietlind L Gerloff (2011). Nucleic Acids Res., 39:D705-11. TEMPORARY DOWNTIME - we are moving BiSC to a new server. Please expect that most interactive functionality of BiSC may be down until early Summer 2017. Basic list-lookup should work. WE APOLOGIZE FOR ANY INCONVENIENCE CAUSED BY DISRUPTION OF OUR SERVICE. Selected web services are available to further investigate the validity of postulated PPI by inspection of their hypothetical modelled interfaces. BISCHom: 200-1000 Å.

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BISC - Binary Interacting SubComplexes | bisc.soe.ucsc.edu Reviews

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Thomas Juettemann and Dietlind L Gerloff (2011). Nucleic Acids Res., 39:D705-11. TEMPORARY DOWNTIME - we are moving BiSC to a new server. Please expect that most interactive functionality of BiSC may be down until early Summer 2017. Basic list-lookup should work. WE APOLOGIZE FOR ANY INCONVENIENCE CAUSED BY DISRUPTION OF OUR SERVICE. Selected web services are available to further investigate the validity of postulated PPI by inspection of their hypothetical modelled interfaces. BISCHom: 200-1000 Å.

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1 binary subcomplex database

2 biogrid

3 intact

4 and hprd

5 overview

6 tutorial

7 about bisc

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BISC - Binary Interacting SubComplexes | bisc.soe.ucsc.edu Reviews

https://bisc.soe.ucsc.edu

Thomas Juettemann and Dietlind L Gerloff (2011). Nucleic Acids Res., 39:D705-11. TEMPORARY DOWNTIME - we are moving BiSC to a new server. Please expect that most interactive functionality of BiSC may be down until early Summer 2017. Basic list-lookup should work. WE APOLOGIZE FOR ANY INCONVENIENCE CAUSED BY DISRUPTION OF OUR SERVICE. Selected web services are available to further investigate the validity of postulated PPI by inspection of their hypothetical modelled interfaces. BISCHom: 200-1000 Å.

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bisc.soe.ucsc.edu

1

BISC - Binary Interacting SubComplexes

https://bisc.soe.ucsc.edu/help/overview.html

BISC (BInary SubComplexes in proteins) is a new protein-protein interaction (PPI) database intending to bridge between the two communities most active in their characterisation: structural biology and functional genomics researchers. BISC allows users to explore known and modellable subcomplex structures in current functional genomics PPI databases in user-friendly manner. It is organized in three main sections:. Characterised SubComplexes (BISCHom BISCHet). Users may want to inspect the surface properti...

2

BISC - Binary Interacting SubComplexes

https://bisc.soe.ucsc.edu/advanced.html

BInary SubComplex Database - Advanced Search. Query Characterised Subomplexes (BISCHom and BISCHet). Keywords, comma separated. Keywords, comma separated. Enter 1 or 2 protein Sequences,FASTA format. Query Modellable Interaction Section (BISC:MI). Browse BISCHom and BISCHet by Interface Size. BISCHom: 200-1000 Å. BISCHom: 1000-5000 Å. BISCHom: 5000-10000 Å. 10000html" BISCHom:10000 Å. BISCHet: 200-1000 Å. BISCHet: 1000-5000 Å. BISCHet: 5000-10000 Å. 10000html" BISCHet:10000 Å.

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Tutorial

https://bisc.soe.ucsc.edu/help/tutorial.html

Templates: All content in BISCHom and BISCHet (BInary SubComplexes Homo-dimeric and Hetero-dimeric). Targets/Modelling Targets/Modellable Interactions: Content of BISC-MI (BInary SubComplexes - Modellable Interactions). A tutorial usage example (Analysis of the proteasome complex) is available here. Several options are available to query BISC. On the front page. Keywords in BISC-MI can be a UniProt accession number. Eg Q9NSY8), part of the protein name (like 'protease') or the scientific organism name.

4

BISC - Binary Interacting SubComplexes

https://bisc.soe.ucsc.edu/about.html

BInary SubComplex Database (BISC). Juettemann (a t) soe.ucsc.edu. Gerloff (a t) soe.ucsc.edu. Users interested in downloading the entire database, please contact the authors. Version or release date. PISA (part of CCP4 suite). 2219 and 2.2.19. University of California, Santa Cruz.

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BISC - Binary Interacting SubComplexes

Thomas Juettemann and Dietlind L Gerloff (2011). Nucleic Acids Res., 39:D705-11. TEMPORARY DOWNTIME - we are moving BiSC to a new server. Please expect that most interactive functionality of BiSC may be down until early Summer 2017. Basic list-lookup should work. WE APOLOGIZE FOR ANY INCONVENIENCE CAUSED BY DISRUPTION OF OUR SERVICE. Selected web services are available to further investigate the validity of postulated PPI by inspection of their hypothetical modelled interfaces. BISCHom: 200-1000 Å.

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