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Mike's Fourth Try

Sunday, April 26, 2015. Blogging My Genome, episode 7: sifting for bad news. This is the seventh in a series of blog posts. About my genome, which I had sequenced through Illuminas Understand Your Genome. Hey, its been awhile! Weve been unbelievably busy. At my company, but Ive been plugging away on my genome analysis slowly. When I last blogged. On a certain variant Id known to look for, but now well sift through the others in my VCF file. Nearly four million of them! 479;SAR=26;SRF=0;SRP=0;SRR=0;TYPE=s...

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Sunday, April 26, 2015. Blogging My Genome, episode 7: sifting for bad news. This is the seventh in a series of blog posts. About my genome, which I had sequenced through Illuminas Understand Your Genome. Hey, its been awhile! Weve been unbelievably busy. At my company, but Ive been plugging away on my genome analysis slowly. When I last blogged. On a certain variant Id known to look for, but now well sift through the others in my VCF file. Nearly four million of them! 479;SAR=26;SRF=0;SRP=0;SRR=0;TYPE=s...

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Mike's Fourth Try | blog.mlin.net Reviews

https://blog.mlin.net

Sunday, April 26, 2015. Blogging My Genome, episode 7: sifting for bad news. This is the seventh in a series of blog posts. About my genome, which I had sequenced through Illuminas Understand Your Genome. Hey, its been awhile! Weve been unbelievably busy. At my company, but Ive been plugging away on my genome analysis slowly. When I last blogged. On a certain variant Id known to look for, but now well sift through the others in my VCF file. Nearly four million of them! 479;SAR=26;SRF=0;SRP=0;SRR=0;TYPE=s...

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blog.mlin.net

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Mike's Fourth Try: Blogging My Genome, episode 7: sifting for bad news

http://blog.mlin.net/2015/04/blogging-my-genome-episode-7-sifting.html

Sunday, April 26, 2015. Blogging My Genome, episode 7: sifting for bad news. This is the seventh in a series of blog posts. About my genome, which I had sequenced through Illumina's Understand Your Genome. Hey, it's been awhile! We've been unbelievably busy. At my company, but I've been plugging away on my genome analysis slowly. When I last blogged. On a certain variant I'd known to look for, but now we'll sift through the others in my VCF file. Nearly four million of them! G ENSG00000187634 ENST0000034...

2

Mike's Fourth Try: May 2013

http://blog.mlin.net/2013_05_01_archive.html

Sunday, May 26, 2013. A taste of molecular phylogenetics in Julia. Ive been meaning for some time to try out Julia. As far as I could tell via Google, no phylogenetic sequence analysis code has been written in Julia, so this seemed like an interesting place to start. In this post, Ill build up some toy code for commonly-used models of molecular sequence evolution as continuous-time Markov processes on a phylogenetic tree. This will enable a little implementation of Felsensteins algorithm. Meme spread thr...

3

Mike's Fourth Try: July 2013

http://blog.mlin.net/2013_07_01_archive.html

Sunday, July 28, 2013. The human population harbors 172 mutations per non-lethal genome position. What'll happen to them? A recent Pandas Thumb post. Highlighted that, given the size of the human genome, the rate of de novo. Point mutations, and the total size of the population, every non-lethal position can be expected to vary - meaning that, for every genome position or site. We are all, regardless of race,. Genetically 99.9% the same. Mutations: what will be their ultimate fate? Links to this post.

4

Mike's Fourth Try: February 2013

http://blog.mlin.net/2013_02_01_archive.html

Wednesday, February 27, 2013. A true story about Big Science. Once, I decided to consult the literature for details about how to perform a certain selection test using PAML. I turned to my officemate Matt. And asked if he knew of any papers using it. He suggested three relevant papers, which indeed described details of that test, at least in their supplements. I was an author on two of those papers! Links to this post. Sunday, February 24, 2013. My thoughts on the immortality of television sets. The manu...

5

Mike's Fourth Try: Blogging My Genome, episode 5: the homozygous designated driver

http://blog.mlin.net/2014/04/blogging-my-genome-episode-5-homozygous.html

Wednesday, April 2, 2014. Blogging My Genome, episode 5: the homozygous designated driver. This is the fifth in a series of blog posts. About my genome, which I recently had sequenced through. Illumina's Understand Your Genome. We manually examined some of my read mappings and called one A/A homozygous variant. I didn't choose this example at random, of course, but rather because it's an interesting variant with a fairly life-altering phenotype. A gene encoding a key enzyme. Kudos to that dude! Without a...

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Mike Lin's Home Page

http://www.mlin.net/CrossHair.shtml

Michael F Lin, PhD. I'm a software engineer and genome scientist in Silicon Valley. I joined DNAnexus. In 2012, following a decade at MIT. And the Kellis lab. You can read my blog. On twitter, look me up. On LinkedIn, peruse my scientific publications. On Google Scholar, or fork my repos. I established mlin.net in 1999 to publish several freeware Windows utilities I'd created, which had millions of users over the following decade. You can still view the classic mlin.net.

mlin.net

Mike Lin's Home Page

http://www.mlin.net/StartupCPL.shtml

Michael F Lin, PhD. I'm a software engineer and genome scientist in Silicon Valley. I joined DNAnexus. In 2012, following a decade at MIT. And the Kellis lab. You can read my blog. On twitter, look me up. On LinkedIn, peruse my scientific publications. On Google Scholar, or fork my repos. I established mlin.net in 1999 to publish several freeware Windows utilities I'd created, which had millions of users over the following decade. You can still view the classic mlin.net.

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blog.mlin.net

Mike's Fourth Try

Sunday, April 26, 2015. Blogging My Genome, episode 7: sifting for bad news. This is the seventh in a series of blog posts. About my genome, which I had sequenced through Illuminas Understand Your Genome. Hey, its been awhile! Weve been unbelievably busy. At my company, but Ive been plugging away on my genome analysis slowly. When I last blogged. On a certain variant Id known to look for, but now well sift through the others in my VCF file. Nearly four million of them! 479;SAR=26;SRF=0;SRP=0;SRR=0;TYPE=s...

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