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MRC Bright Study

mrc bright study into the genetics of hypertension

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MRC Bright Study | brightstudy.ac.uk Reviews
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MRC Bright Study | brightstudy.ac.uk Reviews

https://brightstudy.ac.uk

mrc bright study into the genetics of hypertension

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1

MRC Bright Study

http://www.brightstudy.ac.uk/index.html

The British Genetics of Hypertension (BRIGHT) study is a research collaboration between 6 UK universities with the aim of finding genes causing high blood pressure using large-scale family studies. We hope that the discovery of genes causing high blood pressure will ultimately lead to new diagnostics, improved therapeutic targets and better prediction of those at greatest risk. Nursing and scientific teams.

2

MRC Bright Study

http://www.brightstudy.ac.uk/info/genome_screen_results.html

Nursing and Scientific Teams. Blood pressure may contribute to 50% of the global cardiovascular disease epidemic. By understanding the genes predisposing to common disorders such as human essential hypertension we may gain insights into novel pathophysiological mechanisms and potential therapeutic targets. In the Medical Research Council BRItish Genetics of HyperTension (BRIGHT) study, we aim to identify these genetic factors by scanning the human genome for susceptibility genes for essential hyp...These...

3

MRC Bright Study

http://www.brightstudy.ac.uk/info/sop_9000666.html

Nursing and Scientific Teams. In 2001, under the Human Samples Collection Initiative the BRIGHT study investigators were awarded a strategic grant to perform Epstein Barr virus (EBV) immortalisation of peripheral blood lymphocytes (PBLs) collected from all BRIGHT sibling-pair and TDT trio samples. All DNA samples will subsequently be made into master plates (50ng/ul) for use by investigators. At ECACC, four vials of transformed lymphocytes per individual will be kept and we have agreed that they will...

4

MRC Bright Study

http://www.brightstudy.ac.uk/info/sop_menu.html

Nursing and Scientific Teams. In order to attain consistency in phenotyping, genetic counselling and recruitment procedures the Nurse Co-ordinator developed Standard Operating Procedures (SOPs) accompanied by regular training updates for all the study nurses. Figure 1 will now guide you through the standardised recruitment process for the sib pair study. Should you wish to view some of the documentation used for the study please click on the relevant links. Regional nurse contact details.

5

MRC Bright Study

http://www.brightstudy.ac.uk/info/patient_resources.html

Nursing and Scientific Teams. Sibling pair study (Sib study). Transmission disequlibrium trios (TDT Study). Case control association study.

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oege.org oege.org

OEGE - Online Encyclopedia for Genetic Epidemiology studies

http://www.oege.org/caseandfamstudies.html

OEGE - Online Encyclopedia for Genetic Epidemiology studies. Case and Family Studies. Case and Family Studies. Country then alphabetical order). United States of America. Australian and New Zealand Clinical Trials Registry (ANZCTR):. Hunter DNA Bank for Schizophrenia and Allied Disorders:. Pharmacogenetics of Vascular Disease - RCSI, Dublin, Eire:. 8220;bioresources at SurGen: hypertension and metabolic syndrome phenotypes on 1,400 normal subjects, 125 BPU hypertensives, 260 SPP100-04 hypertensives; ASCO...

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OEGE - Online Encyclopedia for Genetic Epidemiology studies

http://genes.org.uk/caseandfamstudies.html

OEGE - Online Encyclopedia for Genetic Epidemiology studies. Case and Family Studies. Case and Family Studies. Country then alphabetical order). United States of America. Australian and New Zealand Clinical Trials Registry (ANZCTR):. Hunter DNA Bank for Schizophrenia and Allied Disorders:. Pharmacogenetics of Vascular Disease - RCSI, Dublin, Eire:. 8220;bioresources at SurGen: hypertension and metabolic syndrome phenotypes on 1,400 normal subjects, 125 BPU hypertensives, 260 SPP100-04 hypertensives; ASCO...

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The British Genetics of Hypertension (BRIGHT) study is a research collaboration between 6 UK universities with the aim of finding genes causing high blood pressure using large-scale family studies. We hope that the discovery of genes causing high blood pressure will ultimately lead to new diagnostics, improved therapeutic targets and better prediction of those at greatest risk. Nursing and scientific teams.

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