cabenda.com

Cabenda

Cabenda provides services for evaluation of drug activity in the context of the tumour microenvironment. Advanced in-house methodologies allow us to conduct high volume in vivo tumour and in vitro 3-D tissue model screening for quantitative assessment of drug activity. Whole tumour immunostaining -. Advanced microscopy and immunohistochemical staining methodologies that bypass conventional bottlenecks and allow high throughput. Intelligent image analysis -. 3-D tissue based screening -.

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ANDREW MINCHINTON

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VAN●●●VER , BC, V6T 2B5

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AI●@BCCRC.CA

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ANDREW MINCHINTON

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VAN●●●VER , BC, V6T 2B5

CA

1.60●●●●8032

AI●@BCCRC.CA

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<META> DESCRIPTION

Cabenda provides services for evaluation of drug activity in the context of the tumour microenvironment. Advanced in-house methodologies allow us to conduct high volume in vivo tumour and in vitro 3-D tissue model screening for quantitative assessment of drug activity. Whole tumour immunostaining -. Advanced microscopy and immunohistochemical staining methodologies that bypass conventional bottlenecks and allow high throughput. Intelligent image analysis -. 3-D tissue based screening -.

<META> KEYWORDS

1 Cabenda

2 cancer

3 drug

4 penetration

5 diffusion

6 distribution

7 microenvironment

8 multicellular

9 multilayered

10 tumor

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wwwcabenda com,tumour microenvironment,technology,services,publications,download brochure,in vivo,studies,in vitro

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Cabenda | cabenda.com Reviews

https://cabenda.com

Cabenda provides services for evaluation of drug activity in the context of the tumour microenvironment. Advanced in-house methodologies allow us to conduct high volume in vivo tumour and in vitro 3-D tissue model screening for quantitative assessment of drug activity. Whole tumour immunostaining -. Advanced microscopy and immunohistochemical staining methodologies that bypass conventional bottlenecks and allow high throughput. Intelligent image analysis -. 3-D tissue based screening -.

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cabenda.com

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Cabenda

http://www.cabenda.com/services.html

Assays for mapping a number of biological markers relative tumour vasculature. Drug distribution relative vasculature:. Direct evaluation of drugs relative tumour vasculature. Standard growth delay and cell survival:. Standard growth delay and cell survival assay for drugs on their own and in combination with radiotherapy. Direct visualization of drug penetration:. Allows for evaluation of drug penetration under controlled exposures avoiding complications of plasma pharmacokinetics, liver metabolism, ser...

2

Cabenda

http://www.cabenda.com/tm.html

Little is known of the ability of many of the most commonly used anticancer drugs to distribute within solid tumors (9). Measurement of gross tumor drug accumulation is a routine component of new drug development but tells little about extravascular drug distribution, especially in the case of drugs that are highly reactive in tissue. 1 Rubin P and Casarett G. Microcirculation of tumors - Part I: Anatomy, Function and necrosis. Clin. Radiol. 1966;17:220-229. 8 Jain RK. Delivery of molecular and cellu...

3

Cabenda

http://www.cabenda.com/pub.html

Conference Posters and Publications -. Innovative tools for drug discovery. 2014 AACR Annual Meeting San Diego Trastuzumab distribution following bevacizumab. 2014 AACR Annual Meeting San Diego "Camptothecins: tissue dynamics and implications for therapy". 2009 EORTC-NCI-AACR Boston "Targeting the tumour microenvironment: anti-vascular effects of the hypoxic cytotoxin tirapazamine". 2008 EORTC-NCI-AACR Geneva Tight junctions as a limit to Herceptin Penetration? Clin Cancer Res 2008;14(7):2171-79. Tirapaz...

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Cabenda

http://www.cabenda.com/index.html

Cabenda provides services for evaluation of drug activity in the context of the tumour microenvironment. Advanced in-house methodologies allow us to conduct high volume in vivo tumour and in vitro 3-D tissue model screening for quantitative assessment of drug activity. Whole tumour immunostaining -. Advanced microscopy and immunohistochemical staining methodologies that bypass conventional bottlenecks and allow high throughput. Intelligent image analysis -. 3-D tissue based screening -.

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Cabenda

Cabenda provides services for evaluation of drug activity in the context of the tumour microenvironment. Advanced in-house methodologies allow us to conduct high volume in vivo tumour and in vitro 3-D tissue model screening for quantitative assessment of drug activity. Whole tumour immunostaining -. Advanced microscopy and immunohistochemical staining methodologies that bypass conventional bottlenecks and allow high throughput. Intelligent image analysis -. 3-D tissue based screening -.

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