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Tuesday, December 06, 2016. Biologically inert caged GABA. Since the invention of CNB-caged glutamate and GABA by George Hess in 1994, many others labs have introduced other caged versions using different photochemical protecting groups. See my Beilstein J. Org. Chem. 64 73 review for a summary of work up to 2013. In 2000 Molnar reported (Eur J Pharmacol 2000 vol. 391 (3) pp. 255-62) that CNB-GABA blocked GABA-A receptors in neurons (IC-50 = 0.028 mM). In 2009 Yuste and Etchenique reported RuBi-Glu was m...

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cagedcalcium | cagedcalcium.blogspot.com Reviews
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Tuesday, December 06, 2016. Biologically inert caged GABA. Since the invention of CNB-caged glutamate and GABA by George Hess in 1994, many others labs have introduced other caged versions using different photochemical protecting groups. See my Beilstein J. Org. Chem. 64 73 review for a summary of work up to 2013. In 2000 Molnar reported (Eur J Pharmacol 2000 vol. 391 (3) pp. 255-62) that CNB-GABA blocked GABA-A receptors in neurons (IC-50 = 0.028 mM). In 2009 Yuste and Etchenique reported RuBi-Glu was m...
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cagedcalcium | cagedcalcium.blogspot.com Reviews

https://cagedcalcium.blogspot.com

Tuesday, December 06, 2016. Biologically inert caged GABA. Since the invention of CNB-caged glutamate and GABA by George Hess in 1994, many others labs have introduced other caged versions using different photochemical protecting groups. See my Beilstein J. Org. Chem. 64 73 review for a summary of work up to 2013. In 2000 Molnar reported (Eur J Pharmacol 2000 vol. 391 (3) pp. 255-62) that CNB-GABA blocked GABA-A receptors in neurons (IC-50 = 0.028 mM). In 2009 Yuste and Etchenique reported RuBi-Glu was m...

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cagedcalcium: December 2006

http://cagedcalcium.blogspot.com/2006_12_01_archive.html

Saturday, December 30, 2006. End of year rant. I started this weblog at the beginning of this year because I got so pissed off at the wretched News and Views in Nature Methods. That WH Li wrote about our NDBF-EGTA paper. It seems fitting to end with another rant. So what does it take to be news-worthy? Year (April 2005) in Cell. Yes, JAY LENO). What is so inaccurate about this account is the folk who actually pioneered ChR-2 are not even mentioned. Now this is a 3-page article, so don’t tell there is...

2

cagedcalcium

http://cagedcalcium.blogspot.com/2013/05/rite-of-spring.html

Tuesday, May 28, 2013. The Rite of Spring. Posted by graham at 5:25 AM. Philadelphia, United States. View my complete profile. A plea for better reviewing. Winning the Prize(s).

 The SGP 2010 annual me. I have organised the Socie. My laboratory has moved to the Dept. Todays quiz. Which leading journal no longer sho. I dont normally quote verbatim, but fr. Karl is taking over! Karl Deisseroth and co-wor. CaMK-2 activation is synapse specific during LT. Calcium on the brain. Brian Bacskai has a lovely.

3

cagedcalcium: Our world is darker. Leonard Cohen died today.

http://cagedcalcium.blogspot.com/2016/11/our-world-is-darker-leonard-cohen-died.html

Friday, November 11, 2016. Our world is darker. Leonard Cohen died today. What a shitty end to a shitty week*. Listen to this interview on BBC Radio 4, now available on the iplayer (use your computer only). Or better yet, listen to your favorite Cohen album* , mine is "I'm your man", one I first listened to in my favorite city:. Due to cell phones and google our memories are super short, this was the week of the US general election. An especially moving bootleg of The Partisan. Posted by graham at 4:01 PM.

4

cagedcalcium: August 2006

http://cagedcalcium.blogspot.com/2006_08_01_archive.html

Sunday, August 06, 2006. Is there a statute of limitation on citation? When should you cite a journal article? If someone does something for the first time, and you use their work in some way for your own, it is expected that you cite the original work. Is it then acceptable in your next article, to cite your last paper, rather than the original work? Can this not give a mis-impression of originality? Posted by graham at 8:55 AM. Philadelphia, United States. View my complete profile. New GED lab web page.

5

cagedcalcium: January 2006

http://cagedcalcium.blogspot.com/2006_01_01_archive.html

Wednesday, January 11, 2006. Has just posted a highlight of our recent Nature Methods. Paper in their "hot of the press" section. Posted by graham at 1:26 PM. Sunday, January 08, 2006. Inhibtion of leukemia in vivo. Using a synthetic peptide. Walensky et al. published a wonderful paper in Science. 2004) 305: 1466-70 in which they develop a technqiue to enhance the alpha. Double bond) between adjacent turns of the peptide alpha. Helix increases the alpha. Posted by graham at 8:01 AM. If anyone is interest...

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brainwindows.wordpress.com brainwindows.wordpress.com

Drosophila visual system | Brain Windows

https://brainwindows.wordpress.com/2012/10/24/drosophila-visual-system

New tools for peering into the brain…. Click-thru for the original resolution of a fellow Janelian’s Nikon Small World 4th place. Prize winner. Ryan Williamson composed the image. Drosophila melanogaster visual system halfway through pupal development, showing retina (gold), photoreceptor axons (blue), and brain (green) (1500x). Laquo; G-CaMP5 is finally published! Genetically-encoded intracellular EM stain for connectomics. Date : October 24, 2012. FlyFashioNaut Star Bear Publications.

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GCaMP6 plasmids at addgene | Brain Windows

https://brainwindows.wordpress.com/2012/11/08/gcamp6-plasmids-at-addgene

New tools for peering into the brain…. GCaMP6 plasmids at addgene. Are on addgene. Three flavors, fast kinetics or big signals. Bigger responses than OGB-1, some are MUCH bigger. The responses to drifting gratings in visual cortex are spectacular. Sorry no pics for now. Hopefully the reviewers will be nice so we can all read about it soon. Still work to be done getting true 1AP resolution when simultaneously imaging large populations of neurons, but for single neuron imaging. From the SfN abstract :.

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Journal Club | Brain Windows

https://brainwindows.wordpress.com/journal-club

New tools for peering into the brain…. Journal Club #5 – In Vivo Inhibition Dynamics. Inhibition has a powerful role shaping the network dynamics of the cortex, but most studies of inhibitory circuitry are done in brain slice or anesthetized animals. In Membrane potential dynamics of GABAergic neurons in barrel cortex of behaving mice. Journal Club #4 – Photoactivatable Transcription. Journal Club #3 – Rodent Secondary Somatosensory Cortex (SII). Journal Club #2 – A brief history of calcium imaging.

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Philosophy | Brain Windows

https://brainwindows.wordpress.com/philosophy

New tools for peering into the brain…. Here is a collection my writings that are of a more philosophical nature. Freedom of Scientific Information. A brief piece on the flow of scientific knowledge and the merits of a open system of information sharing. The Science of Free Will. Prepared remarks for the Unitarian Universalist congregation in my hometown led off by two readings from Hippocrates and David Foster Wallace. The topic? And is well worth the 10 minute reading time. Leave a Reply Cancel reply.

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Code | Brain Windows

https://brainwindows.wordpress.com/code

New tools for peering into the brain…. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). You are commenting using your WordPress.com account. ( Log Out. You are commenting using your Twitter account. ( Log Out. You are commenting using your Facebook account. ( Log Out. You are commenting using your Google account. ( Log Out. Notify me of new comments via email. Ryohei’s Neuroscience Notes. Blog at WordPress.com.

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Genetically-encoded intracellular EM stain for connectomics | Brain Windows

https://brainwindows.wordpress.com/2012/10/25/genetically-encoded-intracellular-em-stain-for-connectomics

New tools for peering into the brain…. Genetically-encoded intracellular EM stain for connectomics. The field of connectomics. From the Tsien lab, is a genetically-encoded tag that can stain via singlet oxygen generation, but requires light to activate it. In Nature Biotechnology, Alice Ting’s group reports APEX. Laquo; Drosophila visual system. GCaMP6 plasmids at addgene. Date : October 25, 2012. Categories : circuit mapping. Leave a Reply Cancel reply. Enter your comment here. Address never made public).

neuroscience.mssm.edu neuroscience.mssm.edu

Neuroscience Department - Ellis-Davies Lab Research - Optical Methods & Neurophysiology

http://neuroscience.mssm.edu/ellisdavies

Ellis - Davies Lab. OPTICAL METHODS and NEUROPHYSIOLOGY. Graham Ellis-Davies, PhD. My lab uses organic chemistry to develop new optical methods for cell physiology. Caged compounds for multichromic optical interrogation of neural systems.J. M. Amatrudo, J. P. Olson, H. K. Agarwal and G. C. R. Ellis-Davies Eur. J. Neurosci. (2015) 41: 5-16. Click here for more publications→. Meet the team →. Ellis - Davies Laboratory. T 212 241 6958 F 212 828 4221. Chemistry lab An22-053 T212 241 4355. New York, NY 10029.

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BrainStorm | Brain Windows

https://brainwindows.wordpress.com/brainstorm

New tools for peering into the brain…. Project ideas currently under development. BrainStorm 1 : Calcium Memory Sensors. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). You are commenting using your WordPress.com account. ( Log Out. You are commenting using your Twitter account. ( Log Out. You are commenting using your Facebook account. ( Log Out. You are commenting using your Google account. ( Log Out.

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cagedbutterfly1 | Emerging from the darkness of a cocoon

Emerging from the darkness of a cocoon. Doing Some Things Differently. September 5, 2014. Today my hair is a bit oily, as in sticky-oily. It doesn’t look that way but it. That way. I’m sure it will go away. I have noticed that my hair holds a curl much better and I’m not seeing as much silver as before. Is that a bad thing? I cannot wait for my hair to return to a state of normalcy. Making my own soaps should be fun. I can buy everything I need at Michaels or Walmart, right? Then on to buying a house!

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caged but undaunted – stanley l cohen

It’s Not Just Settlements. An Open Letter to American Jews. To some, ignorance is bliss. Comey’s Blindside: You’re Just a Cop. Equality and Justice for All, It Seems, But Palestinians. The lone wolf of Gaza. American Nightmare: the Criminal, Justice System. Israel and Academic Freedom: a Closed Book. When US Congress chases votes and not the law. The Road from Standing Rock to Gaza is a Straight Line. Boycotts, Now and Then: an Open Letter on BDS to the City Council of New York. Declare Victory, Come Home.

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caged home

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cagedcalcium

Tuesday, December 06, 2016. Biologically inert caged GABA. Since the invention of CNB-caged glutamate and GABA by George Hess in 1994, many others labs have introduced other caged versions using different photochemical protecting groups. See my Beilstein J. Org. Chem. 64 73 review for a summary of work up to 2013. In 2000 Molnar reported (Eur J Pharmacol 2000 vol. 391 (3) pp. 255-62) that CNB-GABA blocked GABA-A receptors in neurons (IC-50 = 0.028 mM). In 2009 Yuste and Etchenique reported RuBi-Glu was m...

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CAGED CANARY

Thursday, 30 July 2015. Do You Love Crystals? Auckland, New Zealand Auckland, New Zealand. Friday, 24 July 2015. Monday, 20 July 2015. New in this week. Kyanite. Auckland, New Zealand Auckland, New Zealand. Wednesday, 15 July 2015. It is Yellow Opal! Said to promote inventiveness, creativity and self expression. Also encourages freedom and independence and enhances the imagination. Coming to my online store soon. Auckland, New Zealand Auckland, New Zealand. Shop Crystal Jewellery NZ. Shop New Age Crystals.

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Home

One man and his porsche obsession. There is something that excites me about cars built for motorsport. When I get into a car that has a roll cage, a fire extinguisher, harnesses or an engine kill switch. I cannot describe exactly what it is, but if you have landed on this site no doubt you will probably agree. This site has been put together to document the build of my Porsche 911 964 Carrera 2 into a Cup spec road and track car. The car came with many receipts for the parts and work carried out as well ...

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