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Pipeline - Radius Health

http://www.radiuspharm.com/r-d/pipeline.html

Being Developed for the Potential Use in the Treatment of Osteoporosis. Investigational drug product candidate Abaloparatide-SC. Abaloparatide is a new synthetic peptide analog of hPTHrP (human parathyroid hormone-related protein), a naturally occurring bone building hormone. PTHrP, unlike parathyroid hormone, is critical in the formation of the skeleton, is involved in the regulation of bone formation, and is able to rebuild bone with low associated risk of inducing hypercalcemia as a side effect. Inves...

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Breast Cancer - Radius Health

http://www.radiuspharm.com/r-d/disease-areas/breast-cancer.html

Approximately 70% of breast cancers express the estrogen receptor, or ER, and depend on estrogen signaling for growth and survival. SERDs have the potential to be an emerging class of endocrine therapies that could directly induce estrogen receptor, or ER, degradation, thus potentially enabling them to treat ER-dependent tumors without allowing ligand-independent resistance to develop while potentially being able to act on AI- and SERM-resistant ER-positive tumors.

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Publications - Radius Health

http://www.radiuspharm.com/r-d/publications.html

RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Fiona Garner, Maysoun Shomali, Dotty Paquin, C. Richard Lyttle, Gary Hattersley. May 29-June 2 2015. American Society of Clinical Oncology. A phase 1 study of RAD1901, an oral selective estrogen receptor degrader, in ER positive, HER2 negative, postmenopausal advanced breast cancer patients. San Antonio Breast Cancer -. November 13, 2014. Responder Analysis of...

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Osteoporosis - Radius Health

http://www.radiuspharm.com/r-d/disease-areas/osteoporosis.html

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Management - Radius Health

http://www.radiuspharm.com/about/management.html

President and Chief Executive Officer. Senior Vice President, Chief Financial Officer. Gary Hattersley, PhD. Greg Williams, PhD, MBA. Senior Vice President and General Counsel. Senior Vice President, Head of Global Oncology. Deborah A. Kauffman. Vice President Human Resources. Vice President Corporate Affairs. Vice President Strategic Planning and Corporate Services. Geoffrey A. Swire. Vice President, Business Development and Strategy. Deb received her BA from Franklin and Marshall College. Over the past...

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Vasomotor Symptoms - Radius Health

http://www.radiuspharm.com/r-d/disease-areas/vasomotor-symptoms.html

Radius believes that there is a significant need for new therapeutic options to treat vasomotor symptoms.

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Board of Directors - Radius Health

http://www.radiuspharm.com/about/board-of-directors.html

Kurt C. Graves. Alan H. Auerbach. Willard H. Dere MD. Ansbert K. Gadicke, MD. Dr Dere received a B.A. degree in Zoology and History and an M.D. degree from the University of California, Davis. He has published over 50 articles; wrote and co-edited a primary care textbook; was awarded the 2008 transformational leadership award from UC Davis; and is a fellow in the American College of Physicians. Debasish Roychowdhury is currently President of Nirvan Consultants, LLC and advises biotechnology companies and...

radiuspharm.com

About - Radius Health

http://www.radiuspharm.com/about.html

Radius is a science-driven biopharmaceutical company focused on developing new therapeutics for patients with osteoporosis as well as other serious endocrine-mediated diseases.

radiuspharm.com

Scientific Advisory Board - Radius Health

http://www.radiuspharm.com/about/scientific-advisory-board.html

John Katzenellenbogen, PhD. C Richard Lyttle, PhD. Stavros C. Manolagas, MD, PhD. John T. Potts, MD, DSc. Michael Rosenblatt, MD.