cbf.ox.ac.uk

Home - Clinical BioManufacturing Facility

Contact / Find Us. Welcome to the CBF. The Clinical BioManufacturing Facility (CBF) has over 20 years experience producing biological Investigational Medicinal Products (IMPs) according to GMP for early phase clinical trials. Read more about the CBF. Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against. Infection in Kenyan adults. Science Translational Medicine,. See all related publications. Nuffield Department of Medicine.

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Home - Clinical BioManufacturing Facility | cbf.ox.ac.uk Reviews

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Contact / Find Us. Welcome to the CBF. The Clinical BioManufacturing Facility (CBF) has over 20 years experience producing biological Investigational Medicinal Products (IMPs) according to GMP for early phase clinical trials. Read more about the CBF. Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against. Infection in Kenyan adults. Science Translational Medicine,. See all related publications. Nuffield Department of Medicine.

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3 about us

4 development

5 production

6 quality assurance

7 related publications

8 plasmodium falciparum

9 ogwang c

10 et al

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Home - Clinical BioManufacturing Facility | cbf.ox.ac.uk Reviews

https://cbf.ox.ac.uk

Contact / Find Us. Welcome to the CBF. The Clinical BioManufacturing Facility (CBF) has over 20 years experience producing biological Investigational Medicinal Products (IMPs) according to GMP for early phase clinical trials. Read more about the CBF. Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against. Infection in Kenyan adults. Science Translational Medicine,. See all related publications. Nuffield Department of Medicine.

INTERNAL PAGES

cbf.ox.ac.uk

1

Latest News - Clinical BioManufacturing Facility

http://www.cbf.ox.ac.uk/latest-news

Contact / Find Us. Products and Clinical Trials. Page 1 of 4. CBF listed on KTN’s Innovation Landscape for the Medicines Manufacturing Sector. A new web portal (http:/ www.mmlandscape.ktn-uk.org/) was launched at the recent 12th Annual bioProcessUK Conference held in Cambridge on 25/6 November 2015. The portal developed by the Knowledge Transfer Network (KTN) on behalf of the Medicines Manufacturing Industry Partnership (MMIP) pulls together the innovation landscape, company base and . Good Luck, Phil!

2

Production - Clinical BioManufacturing Facility

http://www.cbf.ox.ac.uk/production

Contact / Find Us. The CBF has a dedicated clean room for the production of master and working cell banks. Once the banks have been checked for sterility and mycoplasma status, they are stored in a liquid nitrogen freezer in vapour phase. A number of vials from all critical cell banks are archived off site at approved storage facilities. 2016 Clinical BioManufacturing Facility, Old Road, Headington, Oxford OX3 7JT Home. Nuffield Department of Medicine.

3

Development - Clinical BioManufacturing Facility

http://www.cbf.ox.ac.uk/development

Contact / Find Us. Upstream and Downstream Development. Process Development is a critical aspect of product development that aims to reduce the costs, risks and timelines for projects entering GMP manufacture. Our Process Development team will:. Define the processing conditions for the GMP manufacture of adenoviral vector products. Ensure that the product is manufactured by a process that maintains the highest standards of product quality, as required by the European Pharmacopoeia for clinical trials.

4

Quality Assurance - Clinical BioManufacturing Facility

http://www.cbf.ox.ac.uk/quality-assurance

Contact / Find Us. Many of the standard in process tests and QC release tests are also carried out in house. These include:. Endotoxin testing (LAL assays). Residual host-cell protein and residual reagents. Antigen detection using a number of different methodologies including FACS analysis, ELISA and Western Blotting. Quantification of virus by total particle number determination using A. Plaque assays, limiting dilution of infectious virus. Nuffield Department of Medicine.

5

Related Publications - Clinical BioManufacturing Facility

http://www.cbf.ox.ac.uk/related-publications

Contact / Find Us. Products and Clinical Trials. Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against. Infection in Kenyan adults. Ogwang C, Kimani D, Edwards NJ, Roberts R, Mwacharo J, Bowyer G, Bliss C, Hodgson SH, Njuguna P, Viebig NK, Nicosia A, Gitau E, Douglas S, Illingworth J, Marsh K, Lawrie A, Imoukhuede EB, Ewer K, Urban BC, Hill AVS, Bejon P, MVVC Group. May 2015. doi:. New England Journal of Medicine. July 2014. ...

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GMP

http://www.setgyc.es/Información-de-Interés/GMP.aspx

Ensayos Clinicos en España. Introducción a la Terapia Génica y la Terapia Celular. Guía para patrocinar la SETGyC. Instalaciones de producción de vectores para investigación y para clínica (GMP). La fabricación de fármacos celulares o génicos según normas GMP para ensayos clínicos puede ser una limitación importante y difícil de superar. Biotec Distribution Wales Limited. Clinical Biomanufacturing Facility, Oxford. Emergent Product Development UK Limited. NHSBT, Clinical Biotechnology Centre.

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Links | www.transvac.org

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EUROPEAN NETWORK OF VACCINE RESEARCH AND DEVELOPMENT. Biomedical Primate Research Centre. BPRC), The Netherlands. Central Veterinary Institute (CVI) of Wageningen UR. University of Oxford, UK. European Commission - Framework Program 7. Helmholtz Centre for Infection Research. London School of Hygiene and Tropical Medicine. Max Planck Institute for Infection Biology. TBVI), The Netherlands. Health Protection Agency, Centre for Emergency Preparedness and Response. CEPR, formerly CAMR), UK.

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http://www.jenner.ac.uk/jobs-2

Working at the Jenner Institute. Meet our Staff and Students. Working at the Jenner Institute. The vaccine development process. Vaccine development is a multi-disciplinary effort which requires expertise from a diversity of areas that range from immunology, structural biology and pathogen genomics, to bioprocessing, delivery technology, field trial design and health economics. Research groups and programmes. Read more about our different research programmes. The Jenner Institute Laboratories. In Headingt...

sftcg.fr

GMP

http://www.sftcg.fr/Generalites/GMP.aspx

Introduction à la Thérapie Génique. La SFTCG et le Public. Centres de Production et de Contrôle de Produits de Thérapie Génique. La production et le contrôle de produits de biothérapie par des laboratoires et sociétés observant des pratiques satisfaisantes aux exigences des agences réglementaires (jusquau stade Bonnes Pratiques de Fabrication BPF) est indispensable pour accéder aux essais cliniques. Gene Therapy, The Time is Now. Click here to visit the bluebird bio site. Biotec Distribution Wales Limited.

ndm.ox.ac.uk

About us - Nuffield Department of Medicine

http://www.ndm.ox.ac.uk/about-ndm

Institutes, Centres, Units. About the Nuffield Department of Medicine. The Nuffield Department of Medicine (NDM) is a large multi-disciplinary department that links high quality clinical research with medical application. The underpinning motivation behind all research carried out by NDM is the pursuit of academic excellence and the positive impact of research on the health and wellbeing of the global community. Are supported by a central administrative team, NDM Strategic. NDM’s diverse research p...

ndm.ox.ac.uk

About us - Nuffield Department of Medicine

http://www.ndm.ox.ac.uk/about-us

Institutes, Centres, Units. About the Nuffield Department of Medicine. The Nuffield Department of Medicine (NDM) is a large multi-disciplinary department that links high quality clinical research with medical application. The underpinning motivation behind all research carried out by NDM is the pursuit of academic excellence and the positive impact of research on the health and wellbeing of the global community. Are supported by a central administrative team, NDM Strategic. NDM’s diverse research p...

esgct.eu

GMP

http://www.esgct.eu/Useful-Information/GMP.aspx

Introduction to Gene Therapy. National Gene and Cell Therapy Societies. Congress Main Scientific Programme. GMP and Research-grade Vector Production Facilities. Biotec Distribution Wales Limited. Clinical Biomanufacturing Facility, Oxford. Emergent Product Development UK Limited. NHSBT, Clinical Biotechnology Centre. Npil Pharmaceuticals (UK) Limited. Omnia Biologics, Inc. Powell Gene Therapy Centre, University of Florida. Texcell, a Pasteur Institute Co. Create a secure account Join.

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cbf.ox.ac.uk

Home - Clinical BioManufacturing Facility

Contact / Find Us. Welcome to the CBF. The Clinical BioManufacturing Facility (CBF) has over 20 years experience producing biological Investigational Medicinal Products (IMPs) according to GMP for early phase clinical trials. Read more about the CBF. Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against. Infection in Kenyan adults. Science Translational Medicine,. See all related publications. Nuffield Department of Medicine.

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