3drepertoire.russelllab.org
Protein Evolution (Rob Russell)
http://www.3drepertoire.russelllab.org/images.shtml
Cancer severity from interaction mechanisms. Figure shows shorter survival across all cancers for tumors with mutations altering the P53-zinc interface (red) compared to others (green). Cancer severity from interaction mechanisms. Figure shows distinct populations within Breast carcinoma according to different mutations at the PIK3CA/PIK3R1 interface. Cancer severity from interaction mechanisms. Cancer severity from interaction mechanisms. Modelling of FFV gag protein. Figure shows the architecture of th...
russelllab.org
Group Members in Protein Evolution
http://www.russelllab.org/group.shtml
Protein-protein interactions, Modelling, Computational administration. Chemistry, Biochemistry, Biophysics and Molecular Biology in the lab. GTPases, Structure, Modifications. YingYing Jiang (PhD Student). Juan-Carlos Gonzales (PhD Student). Protein modifications and structure. Gurdeep Singh (MSc Student). Alumni of the Russell Group. 11/05/2016 Ciliary landscape data now available. 15/04/2015 New group member Juan-Carlos Gonzalez (PhD Student). 27/01/2015 New group member Gurdeep Singh (MSc Student).
russelllab.org
Protein Evolution (Rob Russell)
http://www.russelllab.org/publications.shtml
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Boldt K*, van Reeuwijk J*, Lu Q. Koutroumpas K*, Nguyen TT, Texier Y, van Beersum SEC, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KLM, Arts HH, Betts MJ. Roepman R* Nat Commun. Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia. Lopez C, Bergmann AK, Paul U, Murga-Penas EM, Nagel I, Betts MJ. Schilhabel M, Schlesner M, S...
russelllab.org
Services offered by Protein Evolution
http://www.russelllab.org/services.shtml
This tool lets you interrogate data from our collaborative project on the Ciliary proteome, where we identified nearly 5000 interactions and over 50 complexes, involving more than 1000 proteins in the cilia. From Boldt, van Reeuwijk, Lu, Koutroumpas et al Nat Commun. From Betts et al, Nucl Acids Res. A database of protein-chemical interactions predicted by structure superimpositions: if you are interested in chemicals that might bind a particular protein or vice versa, then check it out. From Stark et al...
mechismo.russelllab.org
Protein Evolution (Rob Russell)
http://www.mechismo.russelllab.org/index.shtml
Cancer severity from interaction mechanisms. Cancer severity from interaction mechanisms. Cancer severity from interaction mechanisms. Cancer severity from interaction mechanisms. Modelling of FFV gag protein. A landscape of the human cilium. A landscape of the human cilium. A landscape of the human cilium. A landscape of the human cilium. Mechismo: Mechanistic interpretation of structural modifications. Mechismo: Mechanistic interpretation of structural modifications. RhoA mutations in Burkitt's lymphoma.
apiclab.org
Biomedical Networks
http://www.apiclab.org/index.shtml
A roadmap for toxicology. Pathway maps for toxicology. Predicting new drug-protein interactions. We are the Cell Networks. Biomedical Networks group based at the University of Heidelberg. Our research is focussed on studying biological networks and using them to make useful predictions in the biomedical sciences. For more information click on Research above. Design based on a template from Free CSS Templates. A landscape of the human cilium (Nat Commun). Toxicology ontology perspectives (ALTEX).
mechismo.russelllab.org
Protein Evolution (Rob Russell)
http://www.mechismo.russelllab.org/publications.shtml
Insights into cancer severity from biomolecular interaction mechanisms. Apic G, Vukotic R, Andreone P, Stein L, Russell RB. Mutagenesis of N-terminal residues of feline foamy virus Gag reveals entirely distinct functions during capsid formation, particle assembly, Gag processing and budding. Liu Y, Betts MJ. Lei J, Wei G, Bao Q, Kehl T, Russell RB. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Boldt K*, van Reeuwijk J*, Lu Q. Roepman R* Nat Commun. DNA methyl...
landscape.syscilia.org
Protein Evolution (Rob Russell)
http://www.landscape.syscilia.org/publications.shtml
Insights into cancer severity from biomolecular interaction mechanisms. Apic G, Vukotic R, Andreone P, Stein L, Russell RB. Mutagenesis of N-terminal residues of feline foamy virus Gag reveals entirely distinct functions during capsid formation, particle assembly, Gag processing and budding. Liu Y, Betts MJ. Lei J, Wei G, Bao Q, Kehl T, Russell RB. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Boldt K*, van Reeuwijk J*, Lu Q. Roepman R* Nat Commun. DNA methyl...
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