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CERRX.COM

Home of CerRx Inc.

Home of CerRx Inc. an intermediate stage targeted anticancer drug discovery and development company

http://www.cerrx.com/

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Childrens Hospital Los Angeles

C Patrick Reynolds

Division of Hemato●●●●●●●●●●●●●●●●●●7 4650 Sunset Blvd

Los ●●●●eles , CA, 90027

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1.32●●●●2207
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Childrens Hospital Los Angeles

C Patrick Reynolds

Division of Hemato●●●●●●●●●●●●●●●●●●7 4650 Sunset Blvd

Los ●●●●eles , CA, 90027

US

1.32●●●●2207
1.32●●●●9445
cp●●●●●●@hsc.usc.edu

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Childrens Hospital Los Angeles

C Patrick Reynolds

Division of Hemato●●●●●●●●●●●●●●●●●●7 4650 Sunset Blvd

Los ●●●●eles , CA, 90027

US

1.32●●●●2207
1.32●●●●9445
cp●●●●●●@hsc.usc.edu

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Home of CerRx Inc. | cerrx.com Reviews

https://cerrx.com

Home of CerRx Inc. an intermediate stage targeted anticancer drug discovery and development company

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1

Biochemical Basis for the CerRx Approach to Cancer Therapy

http://www.cerrx.com/approach.php

Biochemical Basis for the CerRx Approach to Cancer Therapy. The Synthesis of Ceramide Waxes in Cells. Fenretinide stimulates the synthesis of dihydroceramide waxes in cancer cells but not in normal cells. CerRx Founders have shown that dihydroceramide waxes are toxic to cancer cells.

2

Introduction to CerRx, Inc.

http://www.cerrx.com/intro.php

Introduction to CerRx, Inc. CerRx is a class C Delaware Corporation that was founded on December 24, 2008. The mission of CerRx is to improve the lives of cancer patients by bringing to the marketplace, with FDA approval, unique therapeutics that target the ceramide pathway.

3

Initial CerRx Clinical Products

http://www.cerrx.com/products.php

Initial CerRx Clinical Products. CerRx will focus for its initial clinical products on intravenous formulations of two drugs (fenretinide safingol) that have a remarkable synergistic activity at drug levels expected to generate modest systemic toxicity. Synthetic vitamin A-like molecule. Increases ceramide waxes in cancer cells but not in normal cells. Kills cancer cells but not normal cells. Clinically-proven low level of bone marrow toxicity. Clinically-proven absence of mouth lesions and hair loss.

4

CerRx Drug Pipeline

http://www.cerrx.com/pipeline.php

The flagship in the CerRx pipeline is the intravenous (emulsion) fenretinide (4-HPR) formulation (patents issued and licensed to CerRx). Phase II studies of intravenous emulsion fenretinide are being planned with the National Cancer Institute (NCI). Click on the chart below to view a larger version.

5

CerRx Management Team

http://www.cerrx.com/team.php

Richard L. Love, Executive Chairman of the Board. William J. Simpson, Chief Executive Officer. Barry J. Maurer, MD PhD, Chief Medical Officer. C Patrick Reynolds, MD PhD, Chief Scientific Officer. Kerry M. Barnhart, Ph.D., Senior Vice-President, Development.

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