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Importance of Solubility in Pharmacy | chempharming
https://chempharming.wordpress.com/2012/12/04/importance-of-solubility-in-pharmacy
Chemistry and Leukemia-related Pharmacology. December 4, 2012. Importance of Solubility in Pharmacy. Previously, we discussed Synribo, a recently approved drug to treat chronic myelogenous leukemia (CML). However, we also mentioned that it is non-polar in water; thus, in its natural state, Synribo, or Omacetaxine Mepesuccinate, cannot be absorbed in the body that well. Drugs come in many shapes and forms but they all must be somewhat soluble in water to be absorbed in the human body. This makes it even m...
A Different Choice with Different Side Effects | chempharming
https://chempharming.wordpress.com/2013/01/16/a-different-choice-with-different-side-effects
Chemistry and Leukemia-related Pharmacology. January 16, 2013. A Different Choice with Different Side Effects. The blue squiggles represents the Abi kinase domain which is a fancy naming of the white blood cell creator. Within the kinase domain is a red chemical structure which is nilotinib. Tasigna is prescribed as capsules. With any type of medicine, it must be soluble (More on Solubility can be found here. The drug has a chemical formula of C. O and weighs in at a whopping 529.52 g/mole. Anoth...And n...
chempharming | Chemistry & Leukemia-related Pharmacology | Page 2
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Chemistry and Leukemia-related Pharmacology. November 19, 2012. The Search for a Panacea. Previously, we’ve discussed Leukemia. The first example of this is a recent discovery. The use of a patient’s own immune cells to target and destroy cancer such as Leukemia. Image courtesy of CNN. And is only used for educational purposes. To get back to the topic of this blog post, one of the trial participants released an essay. Posted in Chronic lymphocytic leukemia (CLL). November 7, 2012. Is most commonly known...
Synribo and its Speedy Approval to Fight CML | chempharming
https://chempharming.wordpress.com/2012/12/03/synribo-and-its-speedy-approval-to-fight-cml
Chemistry and Leukemia-related Pharmacology. December 3, 2012. Synribo and its Speedy Approval to Fight CML. Tyrosine kinase inhibitor found in today’s drugs to treat CML by normalizing the white blood cell count. (Courtesy: Wikipedia). This drug, however, is not compatible with every patient with CML; the disease mutates to survive traditional treatments. Researchers at the Keck School of Medicine of the University of Southern California discovered that there is a specific protein. Or the Cowtail Pine w...
Gleevec or Glivec, Exactly the Same Thing! | chempharming
https://chempharming.wordpress.com/2012/12/05/gleevec-or-glivec-exactly-the-same-thing
Chemistry and Leukemia-related Pharmacology. December 5, 2012. Gleevec or Glivec, Exactly the Same Thing! The first pharmaceutical drug to note is a drug of two names: Gleevec in the USA, and Glivec everywhere else! It’s certainly an interesting drug. It is marketed by Novartis International AG, a Swiss multinational pharmaceutical company based in Basel, Switzerland. It is considered a mesylate salt, which is any salt or ester of methanesulfonic acid (CH. Methanesulfonic Acid 3D Image. As for the genera...
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About Life With Three Kids – Life With Three Kids
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Life With Three Kids. Life after leukemia – and with three kids! About Life With Three Kids. American Cancer Society’s Relay For Life. Lisy’s Battle with Leukemia. Star Wars, Boyz II Men and Other Things I Like. About Life With Three Kids. What do you do for a living? I’m a father of three, husband of one. My name is Kevin, you can call me Kevin. 8221; emails that had littered my inbox. Since I started in April 2005 Lis has gone from a 3-6 month life sentence to kicking cancer’s butt big time! We (doctor...
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chempharming | Chemistry & Leukemia-related Pharmacology
Chemistry and Leukemia-related Pharmacology. January 20, 2013. Another Day, Another Failsafe. Tasigna and Gleevec are not the only common medicines for CML. Dasatinib was approved by the FDA on June 29, 2006 as Sprycel. Chemical Structure of Dasatinib (Sprycel). Low Red Blood Cell Count. QT interval prolongation (View Tasigna. S QT picture for a better explanation). Congestive Heart Failure (Weakness of the heart that leads to fluid buildup in the lungs). Posted in Chronic myelogenous leukemia (CML).
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