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James Chou

Latest results from the lab. Fas/CD95 is an apoptosis-inducing death receptor. Fu et al. determined the transmembrane domain structure of Fas and showed that the trimer assembly, which is mediated by a proline-containing motif, is essential for Fas signaling. The study is published in Fu et al, Molecular Cell. 2016, 61(4):602-13. 2005 Chou Research Group.

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James Chou | chou.med.harvard.edu Reviews
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Latest results from the lab. Fas/CD95 is an apoptosis-inducing death receptor. Fu et al. determined the transmembrane domain structure of Fas and showed that the trimer assembly, which is mediated by a proline-containing motif, is essential for Fas signaling. The study is published in Fu et al, Molecular Cell. 2016, 61(4):602-13. 2005 Chou Research Group.
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1 biological chemistry and
2 molecular pharmacology
3 contacts
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6 research summary
7 publication
8 position availability
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James Chou | chou.med.harvard.edu Reviews

https://chou.med.harvard.edu

Latest results from the lab. Fas/CD95 is an apoptosis-inducing death receptor. Fu et al. determined the transmembrane domain structure of Fas and showed that the trimer assembly, which is mediated by a proline-containing motif, is essential for Fas signaling. The study is published in Fu et al, Molecular Cell. 2016, 61(4):602-13. 2005 Chou Research Group.

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1

James Chou Lab

http://chou.med.harvard.edu/publication.htm

Equal contribution authors * - corresponding authors. Dev J , Park D , Fu Q, Chen J, Ha HJ, Ghantous F, Herrmann T, Chang W, Liu Z, Frey G, Seaman MS, Chen B*, Chou JJ: Structural Basis for Membrane Anchoring of HIV-1 Envelope Spike. Oxenoid K , Dong Y , Cao C , Cui T , Sancak Y, Markhard AL, Grabarek Z, Kong L, Liu Z, Ouyang B, Cong Y, Mootha VK, Chou JJ: Architecture of the mitochondrial calcium uniporter. 7(4):300-4 (2016). PDF. 25(5):959-73 (2016). PDF. 61(4):602-13 (2016). PDF. Nature Struct Mol Biol.

2

James Chou Lab

http://chou.med.harvard.edu/position.htm

2010 Chou Research Group.

3

James Chou Lab

http://chou.med.harvard.edu/group.htm

James J. Chou. Visiting Graduate Student (Nankai University). Matthew E. Call. Professor and Lab Head. The Walter and Eliza Hall Institute of Medical Research, Australia. Rafal M. Pielak. JiaoTong University, China. Jason R. Schnell. University of Oxford, UK. Academy of Science, Hefei, China. National Center for Protein Sciences, Shanghai, CAS. Research Scientist, Institut de Genomique Fonctionnelle, Dept. de Physiologie, Univ Montpellier. Scientist, Aptitude Medical Systems. Professor and Vice Dean.

4

James Chou

http://chou.med.harvard.edu/index.html

Latest results from the lab. Fas/CD95 is an apoptosis-inducing death receptor. Fu et al. determined the transmembrane domain structure of Fas and showed that the trimer assembly, which is mediated by a proline-containing motif, is essential for Fas signaling. The study is published in Fu et al, Molecular Cell. 2016, 61(4):602-13. 2005 Chou Research Group.

5

James Chou Lab

http://chou.med.harvard.edu/events.htm

2005 Chou Research Group.

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CMCD: The Center for Molecular and Cellular Dynamics - Faculty

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22nd Annual Structural Biology Retreat. July 27, 2016. Stephen C. Harrison. Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School. Children's Hospital Laboratory of Molecular Medicine. Http:/ crystal.harvard.edu. We are structural biologists concerned with the organization and dynamics of macromolecular assemblies. We ask the following kinds of questions: (1) How do viruses assemble and get into and out of cells? Brigham and Women's Hospital, Department of Pathology. Labora...

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Latest results from the lab. Fas/CD95 is an apoptosis-inducing death receptor. Fu et al. determined the transmembrane domain structure of Fas and showed that the trimer assembly, which is mediated by a proline-containing motif, is essential for Fas signaling. The study is published in Fu et al, Molecular Cell. 2016, 61(4):602-13. 2005 Chou Research Group.

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