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The Adams Lab | – the epigenetics of aging and cancer

- the epigenetics of aging and cancer

http://chromatin.wordpress.com/

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The Adams Lab | – the epigenetics of aging and cancer | chromatin.wordpress.com Reviews
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- the epigenetics of aging and cancer
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The Adams Lab | – the epigenetics of aging and cancer | chromatin.wordpress.com Reviews

https://chromatin.wordpress.com

- the epigenetics of aging and cancer

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Publications | The Adams Lab

https://chromatin.wordpress.com/publications

Adams, P.D., Parker, P.J. TPA inducible activation of MAP-kinase. FEBS Lett. 290:77-82, 1991. Adams, P.D., Parker, P.J. Activation of MAP-kinase by a MAP-kinase-kinase. J. Biol. Chem. 267:13127 13130, 1992. Qin, X-Q., Livingston, D.M., Kaelin, W.G. Jr., Adams, P.D. Deregulated E2F-1 expression leads to S phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. U.S.A. 91:10918-10922, 1994. Chen, Y-N. P., Sharma, S.K., Ramsey, T.M., Jiang, L., Martin, M.S., Baker, ...Ma, T, Van Tine, B.A., We...Hall,...

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Lab members | The Adams Lab

https://chromatin.wordpress.com/lab-members

Peter D. Adams, PhD. 8211; p.adams@beatson.gla.ac.uk. Peter Adams obtained his BA in biochemistry at the University of Oxford, England and his PhD at Imperial Cancer Research Fund (now CR-UK). He did post-doctoral work with Dr. William G. Kaelin, Jr. at Dana-Farber Cancer Institute. He set up his own lab at Fox Chase Cancer Center in 1999 and moved to the CR-UK Beatson Institute and Glasgow University in October of 2008. Peter Adams is co-Editor-in-Chief of the journal. Rachael Hewitt, BSc. –. Mohammad I...

3

Collaborations | The Adams Lab

https://chromatin.wordpress.com/collaborations

The lab has extensive collaborations with other labs throughout the world. In particular, we collaborate closely with the labs of Dr. Shelley Berger (University of Pennsylvania, Philadelphia), Ronen Marmorstein (University of Pennsylvania, Philadelphia) and Brad Johnson (University of Pennsylvania, Philadelphia). These collaborations are funded by an NIH program project grant on the “. Epigenetics of aging and age-associated diseases. Http:/ agingepigenetics.wordpress.com/. We have had excellent collabor...

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Research | The Adams Lab

https://chromatin.wordpress.com/projects

Research in the lab focuses on cellular and molecular mechanisms underlying cell and tissue aging, with emphasis on epigenetics and age-associated epigenetic changes that predispose to cancer. We are also interested in developing epigenetic therapies. To combat cancer, and ultimately epigenetic chemopreventative strategies. We employ. Why does the incidence of cancer increase with age? Figure : A model for age-associated increase in cancer incidence . See: Adams, P.D. Jasper, H., Rudolph, K.L&#46...2015 ...

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Positions available | The Adams Lab

https://chromatin.wordpress.com/positions-available

Informal applicants should send a CV and a brief summary of research interests to Professor Peter D. Adams at p.adams@beatson.gla.ac.uk. Create a free website or blog at WordPress.com. Follow “The Adams Lab”. Get every new post delivered to your Inbox. Build a website with WordPress.com.

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Member List | Epigenetics of Aging and Age-Associated Diseases

https://agingepigenetics.wordpress.com/member-list

Epigenetics of Aging and Age-Associated Diseases. Projects and Core Facilities. Project 1: Structural basis for epigenetics in aging and longevity. Project 2: Epigenetics of aging in S. cerevisiae and human cells. Project 3: Epigenetic regulation of senescence in yeast telomerase mutants. Project 4: Epigenetic control of human cell senescence. Core B: Protein and Vector Production. Project Director: Shelley Berger, PhD. Co-Director: Ronen Marmorstein, PhD. Project 1 Personnel ( Ronen Marmorstein, PhD.

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Peter D Adams - Epigenetics of Cancer and Ageing | Beatson Institute

http://www.beatson.gla.ac.uk/cancer-metabolism-growth-and-survival/peter-d-adams-epigenetics-of-cancer-and-ageing.html

Peter D Adams - Epigenetics of Cancer and Ageing. University of Glasgow / Beatson Associate. University of Glasgow webpage. Adams Lab Report 2014. 1993: PhD, Imperial Cancer Research Fund, London, Supervisor Peter Parker. 1989: BSc, Biochemistry, Oxford University, UK. 2008-present: Professor, University of Glasgow, CRUK Beatson Institute. 2008-2011: Associate Professor, Wistar Institute, Philadelphia, USA. 2005-2011: Associate Professor, Drexel University, Philadelphia, USA. Dou Z, Xu C, Donahue G, Shim...

mcbryan.co.uk mcbryan.co.uk

McBryan - Work

http://www.mcbryan.co.uk/work.html

Amazon Development Centre Scotland. Most recently, I've left the academic life and joined Amazon. As a Software Development Engineer. I'm currently working on distributed, big data systems that operate at very low latencies. Strong focus on machine learning, statistical analysis and prediction. Beatson Institute for Cancer Research. My previous position was at the Beatson Institute. In Glasgow within the Peter Adams. My role was bioinformatics which means I was strictly in silico. Methods of choosing app...

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Current Postdoctoral Training Opportunities

http://www.sbpdiscovery.org/careers/Pages/Postdocs.aspx

Tumor Initiation and Maintenance. Cancer Metabolism and Signaling Networks. Tumor Microenvironment and Cancer Immunology. Development, Aging and Regeneration. Bioinformatics and Structural Biology. Genomic Control of Metabolism. Learn more about health conditions and diseases that are related to our areas of research. Neuroscience and Aging Research Center. Infectious and Inflammatory Disease Center. Sanford Children’s Health Research Center. Center for Metabolic Origins of Disease. Life in Our Cities.

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The Knoepfler Lab conducts stem and cancer cell as well as chromatin/epigenetics research at the UC Davis School of Medicine, Sacramento, CA 95817. Please visit Dr. Knoepfler’s departmental site. You can contact Dr. Knoepfler at: knoepfler@ucdavis.edu. The Knoepfler Lab currently receives funding from NIH and the Alex’s Lemonade Stand Foundation.

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In A Sentence .org. The best little site that helps you understand word usage with examples. Chromatin in a sentence. I wonder if Aidens Hi-C method can be refined to determine the exact three dimensional structure of. If a miRNA alters the expression of transcription factors,. Remodeling agents, or other epigenome modifiers, the effect could last long after a person stops eating the miRNA-containing food. As an extreme example, check out this article: (ignore the title, the. Use gapingly in a sentence.

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The Adams Lab | – the epigenetics of aging and cancer

The epigenetics of senescence, aging and cancer. Chromatin assembly factories in senescence? Senescent cells stained to show DNA, blue; PML nuclear bodies, green; and histone chaperone HIRA, red. See Zhang et al, Mol Cell 2005. While age is the biggest single risk factor for most cancers, the reason for this is currently poorly understood (link to Cancer and Aging. For more details). We hypothesize that age-associated changes in chromatin structure, function and regulation contribute to the dramatic ...

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Chromatin Dynamics in Development and Disease. A Marie Sklodowska Curie Actions Innovative Training Network. The basic unit of chromatin is the nucleosome, which is composed of two copies of the histones H2A, H2B, H3 and H4 wrapped with 146 bp of DNA. Based on the decondensed beads-on-a-string. Is how these structures assemble and are maintained in the absence of membranes and moreover what are the kinetics of stable binding and/or rapid exchange of their components. This dynamic assembly and modific...

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What's new in epigenetics and chromatin biology, plus some other stuff I like. The study of chromatin structure and function is one of the most dynamic and. Exciting fields in biology today. Check back often for summaries and discussion. Of the latest breakthroughs in chromatin biology and epigenetics. 1Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. PLoS Genet. 2012 Mar;8(3):e1002576. Epub 2012 Mar 15. Lim CK, Kelley RL. Mallory MJ, Law...

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