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Developing First-in-Class Dual Inhibitors Targeting Both BET Bromodomains and Dopamine Receptor 2 for the Treatment of Cancer

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Developing First-in-Class Dual Inhibitors Targeting Both BET Bromodomains and Dopamine Receptor 2 for the Treatment of Cancer
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Developing First-in-Class Dual Inhibitors Targeting Both BET Bromodomains and Dopamine Receptor 2 for the Treatment of Cancer

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Scientific Advisory Board - ConverGenePharma

http://convergenepharma.com/about-ConVergene/scientific-advisory-board

Jian Jin, Ph.D. Dr Jin is currently. Professor of Structural and Chemical Biology, Oncological Sciences, and Pharmacology at. The Icahn School of Medicine at Mount Sinai. Over the last six years, Dr. Jin's research has. Focused on discovering chemical probes of protein methyltransferases and functionally selective ligands of G protein-coupled receptors. Prior to joining the faculty of the Icahn School of Medicine,. Before moving to the University of North Carolina at Chapel Hill,. Stefan Knapp, Ph.D.

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ConverGenePharma

http://convergenepharma.com/home

Developing Bromodomain and ExtraTerminal (BET) Protein Inhibitors. ConverGene is an early-stage biopharmaceutical company focusing on the discovery and development of novel cancer drugs targeting the root regulatory mechanisms within cancer cells. Our primary goal is the development of small-molecule drugs that target bromodomains, a well-characterized structural feature of proteins which mediate epigenetic changes in DNA and DNA-packaging proteins. Inhibition of BRD4 Suppresses MYC. ACS Med Chem Lett&#4...

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About ConverGene - ConverGenePharma

http://convergenepharma.com/about-ConVergene

ConverGene has discovered and developed a propriety library of small molecules that have profound effects on the MYC gene, a critical oncogene that controls progression of cancer. From this compound library, we have established our first program to develop novel BRD4 inhibitors. ConverGene scientists in conjunction with University of Maryland Baltimore researchers. Design new class of dual BET/PLK1 inhibitors. ACS Med Chem Lett. 2015 May 18;6(7):764-9. ConverGene receives $25,000 IMPACT grant award.

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Management Team - ConverGenePharma

http://convergenepharma.com/about-ConVergene/management-team

Jeffrey W. Strovel, Ph.D. President and Chief Executive Officer. Dr Strovel has led programs for small-molecule drug discovery and development including drug target discovery, hit-to-lead, drug lead optimization, and biomarker discovery and validation. Earlier in his career, Dr. Strovel held positions at the University of Maryland and the National Cancer Institute. Sunil Sharma, MD, FACP. He also serves as the CMO for Beta Cat Pharmaceuticals. Dr Sharma has been involved with over 150 phase 1 and 2 clini...

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Portfolio - Noble Bioventures

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NexImmune Announces $3 Million Financing. Noble Life Sciences Acquires Spring Valley Labs. Specializes in developing targeted small molecule cancer therapies that affect a novel node in the beta catenin cellular control pathway. Beta Cat has a stellar management and advisory team with successful leadership experience in all aspects of cancer drug discovery and development. The company’s first product is poised to enter clinical trials during the next 12-18 months. Nanotechnology developed at Johns Hopkin...

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Both BET Bromodomains and. Dopamine Receptor 2 for the. Treatment of Rare Diseases.

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