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Antibiotics have been called the miracle drugs of the 20th century,. But evolution of bacterial resistance poses an ongoing challenge. Our new drug candidates have entirely novel mechanisms,. Breaking the cycle of bacterial growth and resistance. CRS3123 for treatment of Clostridium difficile. Novel oral agents for treatment of MRSA, VRE and other Gram-positive infections.

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Antibiotics have been called the miracle drugs of the 20th century,. But evolution of bacterial resistance poses an ongoing challenge. Our new drug candidates have entirely novel mechanisms,. Breaking the cycle of bacterial growth and resistance. CRS3123 for treatment of Clostridium difficile. Novel oral agents for treatment of MRSA, VRE and other Gram-positive infections.
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1 crestone inc
2 pipeline
3 people
4 team
5 careers
6 code of ethics
7 news
8 recent news
9 publications
10 infection
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Home | crestonepharma.com Reviews

https://crestonepharma.com

Antibiotics have been called the miracle drugs of the 20th century,. But evolution of bacterial resistance poses an ongoing challenge. Our new drug candidates have entirely novel mechanisms,. Breaking the cycle of bacterial growth and resistance. CRS3123 for treatment of Clostridium difficile. Novel oral agents for treatment of MRSA, VRE and other Gram-positive infections.

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1

News

http://www.crestonepharma.com/index.php/news

July 25, 2014 Crestone was awarded a Phase 1 SBIR grant entitled Optimization and Lead Selection of Novel Antimycobacterial Agents. July 9, 2014 A Phase 1 Multiple Ascending Dose clinical study of CRS3123 was initiated, under sponsorship of NIH. Http:/ www.niaid.nih.gov/news/newsreleases/2014/Pages/CdifficileTrial.aspx. Http:/ www.clinicaltrials.gov/ct2/show/NCT02106338? Term=CRS3123&rank=2http:/ www.clinicaltrials.gov/ct2/show/NCT02106338?

2

Team

http://www.crestonepharma.com/index.php/people/team

Founders and Senior Management. Nebojsa Janjic, Ph.D. Thale Jarvis, Ph.D. John Rohloff, Ph.D. And oseltamivir phosphate (Tamiflu. Urs Ochsner, Ph.D. Joshua Day, Ph.D.

3

Home

http://www.crestonepharma.com/index.php

Antibiotics have been called the miracle drugs of the 20th century,. But evolution of bacterial resistance poses an ongoing challenge. Our new drug candidates have entirely novel mechanisms,. Breaking the cycle of bacterial growth and resistance. CRS3123 for treatment of Clostridium difficile. Novel oral agents for treatment of MRSA, VRE and other Gram-positive infections.

4

Pipeline

http://www.crestonepharma.com/index.php/pipeline

Crestone is a clinical stage company focused on developing small molecule drugs for serious bacterial infections. The R&D pipeline includes several programs that address areas of significant and growing unmet medical need, utilizing with novel mechanism of action agents. CRS3123 for treatment of. DNA Polymerase inhibitors for treatment of Gram-positive infections.

5

DNA

http://www.crestonepharma.com/index.php/dna

Preclinical program targeting antibiotic-resistant Gram-positive infections. MRSA and PRSP pneumonia. We are developing a novel class of small molecule antibiotics targeting PolC, the replicative DNA polymerase in Gram-positive bacteria. By inhibiting a novel bacterial target, these compounds circumvent existing mechanisms of antibiotic resistance. These agents exhibit broad spectrum activity against all clinically significant Gram-positive bacteria, including methicillin-resistant.

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Antibiotics have been called the miracle drugs of the 20th century,. But evolution of bacterial resistance poses an ongoing challenge. Our new drug candidates have entirely novel mechanisms,. Breaking the cycle of bacterial growth and resistance. CRS3123 for treatment of Clostridium difficile. Novel oral agents for treatment of MRSA, VRE and other Gram-positive infections.

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