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Crews Laboratory at Yale University | | crewslab.yale.edu Reviews

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Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). The Next Generation Proteasome Inhibitor. Exploring Cell Biology using Small Molecules. Studying Nature’s Induced Pluripotent Stem Cells (iPSCs). Controlling Intracellular Protein Levels using Small Molecules. The Broad Foci of the Crews Laboratory. John Hines has received the R50 Research Specialists Award. From the National Cancer Institute.

<META> KEYWORDS

1 research

2 carfilzomib/kyprolis

3 chemical biology

4 methionine aminopeptidase 2

5 proteasome inhibitors

6 regenerative biology

7 the undruggable proteome

8 hydrophobic tagging

9 people

10 craig crews biosketch

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research,carfilzomib/kyprolis,chemical biology,methionine aminopeptidase 2,proteasome inhibitors,regenerative biology,the undruggable proteome,hydrophobic tagging,people,craig crews biosketch,publications,group news,lab photos,positions,all news

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Crews Laboratory at Yale University | | crewslab.yale.edu Reviews

https://crewslab.yale.edu

Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). The Next Generation Proteasome Inhibitor. Exploring Cell Biology using Small Molecules. Studying Nature’s Induced Pluripotent Stem Cells (iPSCs). Controlling Intracellular Protein Levels using Small Molecules. The Broad Foci of the Crews Laboratory. John Hines has received the R50 Research Specialists Award. From the National Cancer Institute.

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crewslab.yale.edu

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Lab Photos | Crews Laboratory at Yale University

http://crewslab.yale.edu/lab-photos

Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). Summer 2016 Crews Lab Annual Picnic. November 2015 Craig receives the Yale Cancer Center Translational Research Prize. June 2015 Crews Lab. December 2013 Craig receives CURE's inaugural Entrepreneur of the Year Award. Left to right: David Mack, partner at the law firm of Shipman and Goodwin LLP; Craig M. Crews; Dr. Susan Froshauer, president and CEO of CURE. 1995 The origina...

2

Publications | Crews Laboratory at Yale University

http://crewslab.yale.edu/publications

Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells. Induced Protein Degradation: An Emerging Drug Discovery Paradigm. Lai AC, Crews CM. Nature Reviews Drug Discovery. Targeted Protein Degradation by Small Molecules. Bondeson DP, Crews CM. Small-Mole...

3

Craig Crews Biosketch | Crews Laboratory at Yale University

http://crewslab.yale.edu/people/craig-crews-biosketch

Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). Craig awarded the 2017 AACR Award. For Outstanding Achievement in Chemistry in Cancer Research. John Hines has received the R50 Research Specialists Award. From the National Cancer Institute. Congratulations to Dan Bondeson who received the NCI Predoctoral to Postdoctoral Fellow Transition Award. Content may not have been approved by or reflect the views of Yale University.

4

Positions | Crews Laboratory at Yale University

http://crewslab.yale.edu/positions

Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). Postdoctoral candidates should contact Prof. Crews at craig.crews@yale.edu. Please include a brief statement describing. Why you are interested in the laboratory. The contact information for three references. Preference will be given to candidates who can secure their own postdoctoral funding support. Craig awarded the 2017 AACR Award. From the National Cancer Institute.

5

Group News | Crews Laboratory at Yale University

http://crewslab.yale.edu/group-news

Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). Craig awarded the 2017 AACR Award. For Outstanding Achievement in Chemistry in Cancer Research. John Hines has received the R50 Research Specialists Award. From the National Cancer Institute. Congratulations to Dan Bondeson who received the NCI Predoctoral to Postdoctoral Fellow Transition Award. Craig receives the Yale Cancer Center Translational Research Prize.

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Officers & Committees | ACS Division of Biological Chemistry Website

http://www.divbiolchem.org/officers

ACS Chemistry for Life. ACS DIVISION OF BIOLOGICAL CHEMISTRY. Bylaws and Meeting Minutes. Conferences of Broad Interest. Journal of Biological Chemistry. Officers & Committees. The Division is indebted to the members who have agreed to further its interests by serving as officers or committee members. University of Texas, Austin. Committee Chair, 2014. Committee Chair, 2015. Committee Chair, 2016. Committee Chair, 2017. Advisory Committee (At Large). University of California, Los Angeles.

mcdb.yale.edu

Faculty | Molecular, Cellular and Developmental Biology

http://mcdb.yale.edu/people/faculty

Skip to main content. Molecular, Cellular and Developmental Biology. Asst Prof Mol Cell and Dev Biology. 300 Heffernan Dr #B31, West Haven, CT 06516. Asst Professor Mol Cell and Dev Biol. 219 Prospect St, New Haven, CT 06511-2106. Adjunct Professor Mol Cell and Dev Biology. Henry Ford II Professor of Molecular, Cellular and Developmental Biology; Investigator, Howard Hughes Medical Institute; Chair, Molecular, Cellular and Developmental Biology. 219 Prospect St, New Haven, CT 06511-2106. Leave of absence...

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Leadership | Arvinas

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Skip to main content. Manny Litchman, MD. Timothy Shannon, MD. Timothy Shannon, MD is the Chairman of the Board of Arvinas and a Venture Partner at Canaan Partners. He also serves on the boards of Aldea Pharmaceuticals. Dr Shannon previously was president and chief executive officer of CuraGen, a biopharmaceutical company focused on oncology, after serving as executive vice president of R&D and chief medical officer. He also held positions of increasing responsibility for Bayer’s Pharmaceutical Busin...

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Scientific Advisory Board | Arvinas

http://www.arvinas.com/about/scientific-advisory-board

Skip to main content. Craig M. Crews, Ph.D. Is the Founder and Chief Scientific Advisor of Arvinas as well as the L.B. Cullman Professor of Molecular, Cellular and Developmental Biology, Chemistry and Pharmacology at Yale University. And became carfilzomib/Kyprolis , which received FDA approval for relapsed/refractory multiple myeloma in 2012. Daniel D. Von Hoff, M.D., F.A.C.P. Dr Von Hoff is the past President of the American Association for Cancer Research (the world’s largest cancer research organizat...

chemicalbiology.yale.edu

Faculty | Graduate Studies in Chemical Biology

http://chemicalbiology.yale.edu/faculty

Yale and New Haven. Yale and the World. Graduate Studies in Chemical Biology. Chemistry and Chemical Biology. Graduate Studies in Chemical Biology home. Yale Graduate Studies in Chemical Biology combine the strengths of selected faculty from the departments of Chemistry; Molecular, Cellular and Developmental Biology; Molecular Biophysics and Biochemistry; and Pharmacology. Chemistry and Chemical Biology: Chemical Diversity, Natural Product Mode of Action, and Organic Synthesis. Proteins and Cell Biology).

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Drupal | SNP Technologies

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Skip to main content. Drupal Website Design and Development. Engage with SNP staff to evaluate your organization's web presence and discuss your objectives. Our team recommends solutions to accelerate and achieve your goals. After SNP has assessed your requirements, SNP's solution architects and designers develop a road map for implementation. This road map outlines the requirements of the project, a timeline, scope, and budget. HOW CAN DRUPAL BENEFIT YOUR BUSINESS? We have an established relationship wi...

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Skip to main content. Drupal Website Design and Development. Engage with SNP staff to evaluate your organization's web presence and discuss your objectives. Our team recommends solutions to accelerate and achieve your goals. After SNP has assessed your requirements, SNP's solution architects and designers develop a road map for implementation. This road map outlines the requirements of the project, a timeline, scope, and budget. HOW CAN DRUPAL BENEFIT YOUR BUSINESS? We have an established relationship wi...

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Crews Laboratory at Yale University |

Skip to main content. Crews Laboratory at Yale University. E3 Ubiquitin Ligase Inhibitors. PROTACs (Proteolysis Targeting Chimera). The Next Generation Proteasome Inhibitor. Exploring Cell Biology using Small Molecules. Studying Nature’s Induced Pluripotent Stem Cells (iPSCs). Controlling Intracellular Protein Levels using Small Molecules. The Broad Foci of the Crews Laboratory. John Hines has received the R50 Research Specialists Award. From the National Cancer Institute.

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