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Cryostax | tebu-bio

CryostaX Single-Freeze Pooled Human Hepatocytes

http://cryostax.tebu-bio.com/

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Cryostax | tebu-bio | cryostax.tebu-bio.com Reviews
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CryostaX Single-Freeze Pooled Human Hepatocytes
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1 hepatocytes
2 xenotech
3 pool
4 microsomes
5 ADME
6 liver
7 tox
8 metabolism
9 cryoinjury
10 hepatocyte
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cryoinjury,udp glucuronosyl transferases,characterisation,customisation,thawing procedures,welcome to tebu bios,with cryostax™,the additional cryoinjury,trade;,cryostax,cryostax™,single freeze,process,pooled human hepatocytes,reduced cryoinjury,large lots
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Cryostax | tebu-bio | cryostax.tebu-bio.com Reviews

https://cryostax.tebu-bio.com

CryostaX Single-Freeze Pooled Human Hepatocytes

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1

Free, on-demand custom pooling with no minimum order | tebu-bio

http://cryostax.tebu-bio.com/minisite/106/Customisation.html

Phase I and II Enzymes. Comparison vs. individual. Free, on-demand custom pooling with no minimum order. Design the CYP panel you need with precision! CryostaX™ is flexible and adapts to your needs with no minimum order. XenoTech provides comprehensive, predictable outcomes for your custom pool, taking the guesswork out of your results. Low or high activity pool for selected CYPs. Select by age, gender, ethnicity. Serologic status (CMV free). Quick preparation and delivery. Dont hesitate to contact us.

2

The effects of multiple freezes on the activity of UDP-Glucuronosyl Transferases in Human hepatocytes | tebu-bio

http://cryostax.tebu-bio.com/minisite/101/UDP-Glucuronosyl_Transferases_.html

Phase I and II Enzymes. Comparison vs. individual. Phase I and II Enzymes. The effects of multiple freezes on the activity of UDP-Glucuronosyl Transferases in Human hepatocytes. Why does single freeze make a difference? Are damaged by the freezing and thawing process. XenoTech’s. Unique, patent-pending process used to prepare CryostaX. Eliminates the need for the second freeze used in conventional pooling methods, minimizing cryoinjury. And preserving enzymatic activity. Tebu-bio Antibody Arrays website.

3

Effects of Cryopreservation on Phase I and II Enzymes | tebu-bio

http://cryostax.tebu-bio.com/minisite/100/Phase_I_and_II_Enzymes.html

Phase I and II Enzymes. Comparison vs. individual. Phase I and II Enzymes. Effects of Cryopreservation on Phase I and II Enzymes. Why does single freeze make a difference? Hepatocytes are damaged by the freezing and thawing process. XenoTech’s unique, patent-pending process used to prepare CryostaX, eliminates the need for the second freeze used in conventional pooling methods, thus minimising cryoinjury and preserving enzymatic activity. Tebu-bio Antibody Arrays website. Tebu-bio Cell Migration website.

4

Characterisation provided | tebu-bio

http://cryostax.tebu-bio.com/minisite/102/Characterisation.html

Phase I and II Enzymes. Comparison vs. individual. We stand by the quality of our products. We measure our enzymatic activities using validated methods. Each order of our 10 and 20-donor CryostaX is accompanied by a lot-specific data sheet. CYP2C9 Diclofenac 4 -hydroxylation. CYP2C19 S-Mephenytoin 4 -hydroxylation. CYP3A4/5 Testosterone 6β-hydroxylation. CYP3A4 Midazolam 1 -hydroxylation. Please refer to Pool of 10 and Pool of 20 pages for respective specifications. Tebu-bio Antibody Arrays website.

5

Pool of 20 | tebu-bio

http://cryostax.tebu-bio.com/minisite/104/Pool_of_20.html

Phase I and II Enzymes. Comparison vs. individual. Single Freeze Pooled Cryopreserved. Gender: Males (10), Females (10). Age: 32 - 76 years of age. Race: Caucasian (13), African American (3), Hispanic (2), Indian (1), Pacific Islander (1). Cause of Death: Anoxia (5), Head Trauma (3), Cerebrovascular. Accident (11), Aortic Aneurysm (1). 16 donors positive, 4 donors negative. Assured Minimum Yield: 10.0 x 10. Per vial / 5.0 x 10. Yield and viability are based on experiments performed at XenoTech.

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venaflux.tebu-bio.com venaflux.tebu-bio.com

Primary cells | tebu-bio

http://venaflux.tebu-bio.com/minisite/204/Related_Products.html

Vena 4Y and 4Y2 Biochips. Vena8 with Glass Coverslip. ExiGo - Microfluidic Pump. Are not "stand alone" products but are used with:. Range of primary cells. Range of cell suspensions. Neutrophils, platelets, PBMCs. Fibrinogen, Gelatin and more. Fibrinogen, Gelatin and more. Range of primary cells. Range of cell suspensions. Neutrophils, platelets, PBMCs. Offers these products through their partners. Tebu-bio Antibody Arrays website. Tebu-bio Cell Migration website. Tebu-bio tebu-bio United Kingdom website.

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journals | tebu-bio

http://venaflux.tebu-bio.com/minisite/245/Publications.html

Vena 4Y and 4Y2 Biochips. Vena8 with Glass Coverslip. ExiGo - Microfluidic Pump. See how others have used these biochips. Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking. W, Heinemann A.J Allergy Clin. 2012 Jun 14. [ Epub. Determinants that govern nanoparticle. Uptake by human endothelial cells under flow. Stephen Paul Samuel, Namrata. Toby Paul, Dmitry Kashanin. Valerie A Gerard, Yurii. International Journal of Nanomedicine. Toby Paul, Dmitry Kashanin.

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therapeutic areas microfluidic biochips | tebu-bio

http://venaflux.tebu-bio.com/minisite/190/Applications.html

Vena 4Y and 4Y2 Biochips. Vena8 with Glass Coverslip. ExiGo - Microfluidic Pump. By checking out those applications where the versatile system has been validated. By going through our frequently asked questions. By other researchers using our microfluidics. Tebu-bio Antibody Arrays website. Tebu-bio Cell Migration website. Tebu-bio Stem Cell and Cell Reprogramming website. Tebu-bio tebu-bio United Kingdom website.

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Sandwich-based antibody arrays: the most specific profiling tool | tebu-bio

http://abarray.tebu-bio.com/minisite/85/Target_profiling:_Sandwich-based.html

History: from gene to protein. How to select RayBiotech's Arrays. Antibody arrays products panel. Publications Full Moon Kinome. Tips on sample preparation. Antibody arrays products panel. Sandwich-based antibody arrays: the most specific profiling tool. Compatible with detection in chemiluminescence. Membrane solid support) or fluorescence (glass-slide). Specificity guaranteed by the combination of matching antibodies. No need for any specific device :. Cell and tissue culture supernatant.

ubiquitination.tebu-bio.com ubiquitination.tebu-bio.com

Detection with Ubiquitin affinity matrices | tebu-bio

http://ubiquitination.tebu-bio.com/minisite/138/Detection_with_Ubiquitin_matrices.html

Detection with Ubiquitin matrices. Ubiquitin: WT and Mutants. Detection with Ubiquitin matrices. Detection with Ubiquitin affinity matrices. A Revolution in Polyubiquitin. Traditional strategies leading to the characterization of ubiquitylated. Proteins often require immunoprecipitation. Tag or, the use of Ubiquitin. Antibodies (this latter being expensive for large scale studies). Alternatively, isolation of polyubiquitylated. Proteins can be achieved with certain Ubiquitin. Were developed (Life Sensors).

ubiquitination.tebu-bio.com ubiquitination.tebu-bio.com

UB/UBL-AMC | tebu-bio

http://ubiquitination.tebu-bio.com/minisite/151/UB/UBL-AMC.html

Detection with Ubiquitin matrices. Ubiquitin: WT and Mutants. Ubiquitin: WT and Mutants. The conjugation of the Carboxyl extremity of mature Ubiquitin. With AMC quenches the intrinsic fluorescence of AMC. Upon incubation with a protease recognizing Ubiquitin. AMC is released and the increase in fluorescence can be measured using Ex380. To determine the activity and specificity of Ubiquitin. High throughput screening for modulators of Deubiquitylase. Tebu-bio Antibody Arrays website.

ubiquitination.tebu-bio.com ubiquitination.tebu-bio.com

Ubiquitin-TAMRA | tebu-bio

http://ubiquitination.tebu-bio.com/minisite/248/UB_-TAMRA.html

Detection with Ubiquitin matrices. Ubiquitin: WT and Mutants. Ubiquitin: WT and Mutants. DUB Fluorescence Polarization Substrate. Is an ideal fluorescence polarization substrate for deubiquitinating. Enzymes. The substrate consists of a 5-carboxytetramethylrhodamine. Where the Ɛ-amino group of Lys. Is linked to the C-terminus of ubiquitin. The substrate allows continuous fluorescence polarization measurement of cleavage of the isopeptide. And the Ɛ-amino group of Lys. By MS ( calc.

ubiquitination.tebu-bio.com ubiquitination.tebu-bio.com

UB/UBL-Rhodamine | tebu-bio

http://ubiquitination.tebu-bio.com/minisite/150/UB/UBL-Rhodamine.html

Detection with Ubiquitin matrices. Ubiquitin: WT and Mutants. Ubiquitin: WT and Mutants. Is a quenched and fluorescent substrate for Deubiquitylases. In particular for Ubiquitin. Cleavage of the amide bond between the C-terminal glycine. Results in an increase in Rhodamine. Fluorescence at 535 nm ( Exc. Is a quenched fluorescent substrate for Desumoylases. Protease 1 ( SenP1. Cleavage of the amide bond between the C-terminal glycine. 110 resulting in an increase in Rhodamine. Fluorescence at 520 nm ( Exc.

ubiquitination.tebu-bio.com ubiquitination.tebu-bio.com

CHOP Isopeptidase Assay | tebu-bio

http://ubiquitination.tebu-bio.com/minisite/155/Isopeptidase_activity.html

Detection with Ubiquitin matrices. Ubiquitin: WT and Mutants. CHOP: a revolutionary technology for characterizing. CHOP-Reporter technology offers a rapid. Activity. Previous Ub. Assays relied on the fusion of small chemical adducts to the C-terminus of the Ub. In many cases this molecule is not recognized by the Isopeptidase. Of interest. The CHOP assay platforms utilize protein fusions. Which are more physiologically relevant and can be recognized by Isopeptidases. That do not recognize other substrates.

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Phase I and II Enzymes. Comparison vs. individual. Mini-website dedicated to Cryostax™. Gain more predictable and accurate results from pooled hepatocytes. A unique approach measures each pool’s characterisation. Before and after pooling, for a double measure of quality control. Our single freeze process provides the highest enzymatic activity possible by minimising. Caused by a second freeze required by conventional pooling methods. We invite you to discover Cryostax. Patent pending single-freeze process.

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