davidquigley.com

David Quigley - UCSF - Cancer Genetics

David Quigley, PhD. Research Summary - CV. I am a translational geneticist focused on improving outcomes for patients whose tumors bear DNA repair defects, in particular patients with metastatic prostate cancer. My research in Alan Ashworth’s laboratory. At the UCSF Helen Diller Comprehensive Cancer Center. Provided the first demonstration of multi-clonal BRCA2. Reversion mutations in metastatic prostate cancer patients who developed resistance to talazoparib and olaparib using liquid biopsy. University ...

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David Quigley - UCSF - Cancer Genetics | davidquigley.com Reviews

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David Quigley, PhD. Research Summary - CV. I am a translational geneticist focused on improving outcomes for patients whose tumors bear DNA repair defects, in particular patients with metastatic prostate cancer. My research in Alan Ashworth’s laboratory. At the UCSF Helen Diller Comprehensive Cancer Center. Provided the first demonstration of multi-clonal BRCA2. Reversion mutations in metastatic prostate cancer patients who developed resistance to talazoparib and olaparib using liquid biopsy. University ...

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1 publications

2 carmen

3 equalizer

4 talks

5 introduction

6 email

7 davidquigley

8 at ucsf edu

9 address

10 quigley et al

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David Quigley - UCSF - Cancer Genetics | davidquigley.com Reviews

https://davidquigley.com

David Quigley, PhD. Research Summary - CV. I am a translational geneticist focused on improving outcomes for patients whose tumors bear DNA repair defects, in particular patients with metastatic prostate cancer. My research in Alan Ashworth’s laboratory. At the UCSF Helen Diller Comprehensive Cancer Center. Provided the first demonstration of multi-clonal BRCA2. Reversion mutations in metastatic prostate cancer patients who developed resistance to talazoparib and olaparib using liquid biopsy. University ...

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davidquigley.com

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David Quigley - UCSF - Cancer Genetics - equalizer

http://www.davidquigley.com/equalizer.html

Affymetrix microarrays are designed using a reference genome from human, mouse, or another organism. Single Nucleotide Polymorphisms (SNPs) in the genomes of individual humans and model organisms that vary from the reference annotations affect the binding of cDNA to microarray probes, affecting the results of experiments measuring gene expression in organisms with distinct genomes. Genetic experiments performed using these arrays are subject to systemic bias unless the effect of these SNPs is acc...And t...

2

David Quigley - UCSF - Cancer Genetics

http://www.davidquigley.com/index.html

David Quigley, PhD. Research Summary - CV. I study how tumor progression and the tumor microenvironment affect the genetic architecture of cancer. I was the first member of Alan Ashworth's. Lab at the UCSF Helen Diller Comprehensive Cancer Center. In 2015 I joined the UCSF Department of Epidemiology and Biostatistics. As an Assistant Adjunct Professor. For the previous eight years I was in Allan Balmain's laboratory. At UCSF. In October 2014 I defended my PhD thesis in the Department of Genetics. Approac...

3

David Quigley - UCSF - Cancer Genetics - Publications

http://www.davidquigley.com/publications.html

David Quigley, PhD. Age, estrogen, and immune response in breast adenocarcinoma and adjacent normal tissue. Tahiri A, Lüders T, Riis MH., Balmain A Børresen-Dale A, Bukholm I, Kristensen V. Code and data to reproduce. Gene expression architecture of mouse dorsal and tail skin reveals functional differences in inflammation and cancer. Kandyba E, Huang P, Halliwill K, Sjölund J, Pelorosso F, Wong C, Hirst G, Wu D, Delrosario R, Kumar A, and Balmain A. Code and data to reproduce. Hackett C, Quigley DA.

4

David Quigley - UCSF - Cancer Genetics - CARMEN

http://www.davidquigley.com/carmen.html

CARMEN is a point-and-click application that permits plotting gene expression. And differential expression analysis. What can it do? The principle functions of CARMEN are:. Plot gene expression data. Calculate Correlation between genes. Generate Correlation networks and export them to Cytoscape. Calculate Differential Expression between two conditions. Find annotations for genes, or genes which match a GO annotation. What do I Need to Run CARMEN? You can get started with data sets we have prepared for you.

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David Quigley - UCSF - Cancer Genetics - Reproducible Results

http://www.davidquigley.com/reproduce.html

Reproducible Results - CARMEN. Although I try to spend as much time working on biology as I can, I write a lot of software in R. Python, and C . For software engineering with C I make heavy use of the Boost. For cross-platform software development. Source code for my software, including CARMEN. Is available at github.com/DavidQuigley. Quigley et al. Nature 2009. Raw expression data for this paper (Affymetrix CEL files) are available at GEO, GSE12248. Software that I wrote. BIN EQTL=/notebook/code/src/eqt...

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David Quigley - UCSF - Cancer Genetics

David Quigley, PhD. Research Summary - CV. I am a translational geneticist focused on improving outcomes for patients whose tumors bear DNA repair defects, in particular patients with metastatic prostate cancer. My research in Alan Ashworth’s laboratory. At the UCSF Helen Diller Comprehensive Cancer Center. Provided the first demonstration of multi-clonal BRCA2. Reversion mutations in metastatic prostate cancer patients who developed resistance to talazoparib and olaparib using liquid biopsy. University ...

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David Quigley | usable technology, connecting people

February 8, 2015. What’s wrong with this question from a web form I recently came across? Creating great web forms is not easy. There are so many details to get right, and you really need to consider who your particular audience is. In this case one improvement that could be made would be to order the options in age order instead of alphabetical order. So for example:. 16 – 18. September 3, 2014. Key Performance Indicators (KPI’s). Awareness / New Audience Development. Because we’re a niche broadca...

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The practice has developed an international client base with projects completed in Paris, Barcelona, Istanbul and throughout the UK. The projects range from one off individual houses to large housing developments for developers and Housing Associations. Leisure projects have included refurbishment of the Winter Gardens in Blackpool, small flower shops on the Strand, London and refurbishment and alteration to Rules restaurant on Maiden Lane, London.

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998 Parkland Drive, Suite 104. Healthy smiles for life! Welcome to David Quigley Dentistry in Halifax. We provide a full suite of modern dental services including sedation dentistry, implant dentistry, family dentistry, cosmetic and restorative dentistry, orthodontics (Invisalign), oral hygiene, oral surgery (wisdom tooth removal), and a wide range of other services. Our compassionate and friendly team is ready to put you at ease. Give us a call today. And patient education videos.

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Life is full of moments, places, people and creatures that you wish you could just hold onto forever. I look for those moments and my camera is my tool at capturing them. I am constantly striving to improve my skills and sharing my photos with others is my reward. David - Mt. Washington Summit - August 28, 2009. Dave getting ready for a shot Feb - 2006 -. Dave setting up for a shot! Along the Glen Ellis River. - New Hampshire.