We will investigate how defects in DNA damage response and repair pathways can be used for developing rational therapies in breast and ovarian cancer, in particular therapy strategies using PARP inhibitors.
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We will investigate how defects in DNA damage response and repair pathways can be used for developing rational therapies in breast and ovarian cancer, in particular therapy strategies using PARP inhibitors.
ddresponse.eu
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Template design: Andreas Viklund. Graphics: Tom de Vries Lentsch. DDResponse is a Collaborative Project funded by the 7th Framework Programme of the European Commission in the theme Health. The start date of the project is 1 February 2011. It will end on 31 January 2015.
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Overall strategy and general description.
DDResponse
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Overall strategy and general description. Genetic (synthetic lethality) and proteomic screens of model organisms (C. elegans, S. cerevisiae) and mammalian cell lines will be carried out to discover novel therapeutic approaches that exploit individual tumour-specific DNA repair deficiencies. These approaches may extend the spectrum of tumours targeted by PARP inhibitors and may lead to novel drugs that exploit other DDR defects in tumours. Overall strategy and general description.
DDResponse
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To belong to the 10 most important breakthroughs in the entire spectrum of sciences in 2009 and the most pertinent development in the wide field of Cancer Research ( Highlight. P 961, 2009). It is the treatment par example of tailor-made, very effective cancer therapy, with comparatively minimal side effects. In this regard, the selective action of PARP inhibition on BRCA1/2 deficient tumours appears to be a 'magic bullet' therapy for this type of cancer. The DNA damage response.
DDResponse
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DDResponse is a Collaborative Project funded by the 7th Framework Programme of the European Commission in the theme Health. The start date of the project is 1 February 2011. It will end on 31 January 2015. DDReponse - New hope for hereditary breast and ovarian cancer patients. Mark OConnor, senior scientist of AstraZeneca (UK), and Jan Hoeijmakers, professor in Genetics at Erasmus MC (NL) highlight the scientific basis for the new treatment and explain why this new treatment is so effective. One of the ...
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Theater van de Wetenschap. Theater van de Wetenschap. Theater van de Wetenschap. Met diverse live optredens. Theater van de Wetenschap. Drie zondagen in theater Bonheur. Theater van de Wetenschap. In gesprek met een wetenschapper. Theater van de Wetenschap. Geniet van muziek, film, dans en natuurlijk wetenschap. Theater van de Wetenschap. Science4you kijkt terug op een geslaagde serie Theater van de Wetenschap. Hieronder de foto-impressies van de drie voorstellingen. Met Gert Jansen, celbioloog Erasmus MC.
We are honored to welcome Mark O’Connor (AstraZeneca) as keynote speaker
http://personalizedmed.eu/we-are-honored-to-welcome-mark-oconnor-astrazeneca-as-keynote-speaker
We are honored to welcome Mark O’Connor (AstraZeneca) as keynote speaker. 2nd Transatlantic conference on personalized medicine. 8-9 october 2015, Erasmus MC, Rotterdam, the Netherlands. We are honored to welcome Mark O’Connor (AstraZeneca) as keynote speaker. Dr O’Connor, Senior Principal Scientist at AstraZeneca will present on the topic of breast cancer. He was also involved in DDReponse – New hope for hereditary breast and ovarian cancer patients. New England Journal of Medicine. Keep me up to date.
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DDResponse
DDResponse is a Collaborative Project funded by the 7th Framework Programme of the European Commission in the theme Health. The start date of the project is 1 February 2011. It will end on 31 January 2015. DDReponse - New hope for hereditary breast and ovarian cancer patients. Mark OConnor, senior scientist of AstraZeneca (UK), and Jan Hoeijmakers, professor in Genetics at Erasmus MC (NL) highlight the scientific basis for the new treatment and explain why this new treatment is so effective. One of the ...
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