designer-drug.com

opioids.com

Use of µ-opiate agonists oxycodone and oxymorphone to treat major depression

http://www.opioids.com/antidepressant/opiate.html

Source: American Journal of Psychiatry. Date: 156:2017, December 1999. Treatment Augmentation With Opiates in Severe and Refractory Major Depression. ANDREW L. STOLL, M.D. and STEPHANIE RUETER, B.A. Letter to the Editor. To the Editor: Substantial evidence supports the antidepressant efficacy of opiates (1). This report summarizes our open-label experience using the µ-opiate agonists oxycodone or oxymorphone in patients with highly refractory and chronic major depression. We used oxycodone in three addit...

opioids.com

Naltrexone ( Trexan ) and suicide

http://opioids.com/naltrexone/suicide.html

Australia: Suicides, Overdoses Linked To Detox Drug. URL: http:/ www.mapinc.org/drugnews/v01/n1008/a07.html. Pubdate: Wed, 06 Jun 2001. Source: Courier-Mail, The (Australia). Contact: cmletters@qnp.newsltd.com.au. Website: http:/ www.thecouriermail.com.au/. Details: http:/ www.mapinc.org/media/98. Authors: Catriona Mathewson, Sean Parnell. SUICIDES, OVERDOSES LINKED TO DETOX DRUG. Mr Beattie, who conceded he had not been fully briefed on the investigation, said there were "difficulties" in the relationsh...

opioids.com

Opioids : past, present and future

http://opioids.com/index.html

THE BIRTH OF A NEW GENERATION. Of the population only feel truly well on opioids. In effect, they self-medicate. Taking responsibility for their own mental health in defiance of medical orthodoxy. It would indeed be extraordinary if - alone among the neurotransmitter systems of the brain - the endogenous opioid families. Were immune from dysfunction. Enkephalins. To "basal hedonic tone" i.e. whether we naturally feel happy or sad. Yet the therapeutic. Today, by contrast, immense energy is devoted by the ...

mdma.net

MDMA in a Psychotherapeutic Context

http://www.mdma.net/misc/liftingtheveil.html

Lifting the Veil: A Review of the History, Clinical-Usage and. Safety of LSD, Ibogaine and MDMA in a Psychotherapeutic Context. By Christopher D. Lovett. The University of Arizona. Program in Cognition and Neural Systems. Part IV - MDMA. My throat is dry.". I'll get you a glass of water." Which I did. It did no good. I'm having trouble breathing.". Do you think I smoke too much? Do you think you smoke too much? I don't think so.". Then the answer is: probably not.". It was now an hour into the experiment...

wireheading.com

Happiness, hypermotivation and the meaning of life

http://www.wireheading.com/hypermotivation.html

And the Meaning Of Life. Video clip (WMV; 0.94Mb) of an Olds' rat crossing an. Electrified grid to self-stimulate its pleasure-centres. Stepping on a strongly electrified grid is highly aversive. A desperately hungry rat - even a rat who hasn't eaten for 10 days - won't run across an electrified cage-floor to reach a food-source: the shocks are too painful. But a rat with electrodes implanted in its neural reward circuitry will. Cross the grid, repeatedly, to gain the chance to self-stimulate. That regul...

dimethyltryptamine.com

DMT

http://www.dimethyltryptamine.com/synthesis.html

Tryptamines I Have Known And Loved. 6 DMT TRYPTAMINE, N,N-DIMETHYL; INDOLE, 3-[2-(DIMETHYLAMINO)ETHYL]; N,N-DIMETHYLTRYPTAMINE; 3-[2-(DIMETHYLAMINO)ETHYL]INDOLE; DESOXYBUFOTENINE; NIGERINE. There are several comments to be made as to salts, melting points, and spectra. 60 - 100 mg (intramuscularly). 60 - 100 mg (subcutaneously). 60 - 100 mg (smoking). 4 - 30 mg (intravenously). With 150 mg, orally) "No observable psychic or vegetative effects.". With 250 mg, orally) "It was inactive.". With 80 mg, intram...