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This web page was produced as an assignment for Genetics 677. An undergraduate course in UW-Madison. GSK3 and Congenital Heart Defect. Introduction to congenital heart defects. According to National Institute of Health [4]. Figure 1Heart Structure [4]. Congenital heart defects. Retrieved January 31,. Http:/ www.nhlbi.nih.gov/health/dci/index.html. GSK 3-beta and its role in cardiac morphogenesis. Figure 2). The enzyme has two isoforms GSK3-alfa and GSK3-beta [5]. Scientists are further trying to determin...

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DimitrovaGen677S09 - Home | dimitrovagen677s09.weebly.com Reviews

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This web page was produced as an assignment for Genetics 677. An undergraduate course in UW-Madison. GSK3 and Congenital Heart Defect. Introduction to congenital heart defects. According to National Institute of Health [4]. Figure 1Heart Structure [4]. Congenital heart defects. Retrieved January 31,. Http:/ www.nhlbi.nih.gov/health/dci/index.html. GSK 3-beta and its role in cardiac morphogenesis. Figure 2). The enzyme has two isoforms GSK3-alfa and GSK3-beta [5]. Scientists are further trying to determin...

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1 gene information

2 homology

3 phylogeny

4 phenotypes

5 structure/function

6 dna motifs

7 protein domains

8 protein interactions

9 miscellaneous

10 references

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gene information,homology,phylogeny,phenotypes,structure/function,dna motifs,protein domains,protein interactions,miscellaneous,references,literature,lycogen s,ynthase k,inase 3,figure 2,pathway description,visitor map,contact information,eva dimitrova

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DimitrovaGen677S09 - Home | dimitrovagen677s09.weebly.com Reviews

https://dimitrovagen677s09.weebly.com

This web page was produced as an assignment for Genetics 677. An undergraduate course in UW-Madison. GSK3 and Congenital Heart Defect. Introduction to congenital heart defects. According to National Institute of Health [4]. Figure 1Heart Structure [4]. Congenital heart defects. Retrieved January 31,. Http:/ www.nhlbi.nih.gov/health/dci/index.html. GSK 3-beta and its role in cardiac morphogenesis. Figure 2). The enzyme has two isoforms GSK3-alfa and GSK3-beta [5]. Scientists are further trying to determin...

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dimitrovagen677s09.weebly.com

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DNA motifs - DimitrovaGen677S09

http://dimitrovagen677s09.weebly.com/dna-motifs.html

This web page was produced as an assignment for Genetics 677. An undergraduate course in UW Madison. The reason why I found these factors particularly interesting is that some researchers (et al Kerkela, 2008; et al Hardt, 2002) identified NF-ATc,GATA4, Cylin D1 and c-Myc as major genes involved. Even though only NF-ATc was the only one from the above list, suggested by the database to have some influence on the GSK3B expression, GATA family transcription factors also might be interesting to investigate.

2

Protein interactions - DimitrovaGen677S09

http://dimitrovagen677s09.weebly.com/protein-interactions.html

This web page was produced as an assignment for Genetics 677. An undergraduate course in UW Madison. Homo sapiens GSK3b interactions. Mus musculus GSK3B interactions. Ndash; axin1;. Beta-transducin repeat containing protein. Frequently rearranged in advanced T-cell lymphomas 2. Dishevelled, dsh homolog 1 (Drosophila). Data retrieved from SRING website:. Http:/ string.embl.de. Networks for GSK3B and GATAs transcription factors as well as GSK3 and the genes involved in cardiac hypertrophy. Back to Home page.

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Miscellaneous - DimitrovaGen677S09

http://dimitrovagen677s09.weebly.com/miscellaneous.html

This web page was produced as an assignment for. An undergraduate course in UW Madison. GATA transcription factor family. Based on the observations that GATA transcription factors seemed to appear several times during my research I decided to investigate what is known for these proteins and what pathways are they involved in. The data I retrieved from GeneCards and SMART gave me the following summary:. Zinc finger transcription factors (they have two tandem zinc finger domains) and. The alignment of thei...

4

Protein domains - DimitrovaGen677S09

http://dimitrovagen677s09.weebly.com/protein-domains.html

This web page was produced as an assignment for Genetics 677. An undergraduate course in UW-Madison. Homology in the protein domains. All three web-based programs ( SMART. Identify a key Serine/ Threonine Kinase domain in the structure of the GSK3B. This domain is found in variety of species and seems to be highly conserved. For my analysis I will use data obtained primarily from Prosite to demonstrate the common elements between the homologues of GSK3B. Back to Home page. Http:/ www.expasy.ch.

5

Structure/Function - DimitrovaGen677S09

http://dimitrovagen677s09.weebly.com/structurefunction.html

This web page was produced as an assignment for Genetics 677. An undergraduate course in UW Madison. The complexity of GSK3B and GO. Wnt receptor signaling pathway through beta-catenin. Positive regulation of protein complex assembly. Positive regulation of protein export from nucleus. Glycogen synthase kinase 3 activity. Protein kinase A catalytic subunit binding. Data retrieved from UniProt. Http:/ www.uniprot.org. Structure and Function in general. All three web-based programs ( SMART. In this region ...

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DimitrovaGen677S09 - Home

This web page was produced as an assignment for Genetics 677. An undergraduate course in UW-Madison. GSK3 and Congenital Heart Defect. Introduction to congenital heart defects. According to National Institute of Health [4]. Figure 1Heart Structure [4]. Congenital heart defects. Retrieved January 31,. Http:/ www.nhlbi.nih.gov/health/dci/index.html. GSK 3-beta and its role in cardiac morphogenesis. Figure 2). The enzyme has two isoforms GSK3-alfa and GSK3-beta [5]. Scientists are further trying to determin...

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