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Brennan Crystallography Research Laboratory. About Dr. Brennan. History of the Lab.

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Brennan Crystallography Research Laboratory. About Dr. Brennan. History of the Lab.
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Current Members

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Brennan Crystallography Research Laboratory. The major invasive fungal pathogens ( Candida albicans. Cryptococcus infection has become one of the leading causes of death among immunocompromised people around the world. It has been found that trehalose is very essential for Cryptococcus to maintain its virulence. Disruption of trehalose synthesis pathway reduces or even abolishes the virulence of Cryptococcus in rabbits, conferring this pathway a very good antifungal drug target.Therefore, my ...HipA is a...

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Publications

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Brennan Crystallography Research Laboratory. Selected Publications Highlighting Brennan Laboratory Research. Schumacher, M.A.*, Balani, P. Min, J., Chinnam, N.b., Hansen, S., Vulic, M., Lewis,K.*, Brennan R.G.*. Co-corresponding authors). HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Cuthbert, B. J., Brennan R.G.*. Schindler, B.D., Seo, S.M., Birukou,I., Brennan, R.G. J Bacteriol. (2015). Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.

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Brennan Crystallography Research Laboratory. About Dr. Brennan. History of the Lab.

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Past Members

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Brennan Crystallography Research Laboratory. Maria A. Schumacher, Ph.D. Graduate Student and Postdoctoral Fellow. Professor at Duke University. Ekaterina E. Heldwein, Ph.D. Associate Professor at Tufts University Medical School. Joy L Huffman, Ph.D. Director of Strategic Planning, Pfizer. Michael H. Godsey, Ph.D. Associate Professor at Concordia College. Gregory S. Allen, Ph.D. Postdoctoral Fellow at SUNY Albany with Dr. Joachim Frank (2003 - 2008). Minsun Hong, Ph.D. Benjamin E. Brooks, Ph.D. Cynthia L&...

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Brennan Crystallography Research Laboratory. Keri Hamilton, Ph.D. Yi Miao, Ph.D., and Tien-Jui Yen, Ph.D. Congratulations to Dr. Keri Hamilton, Dr. Yi Miao and Dr. Tien-Jui Yen, all of whom successfully defended their theses in the month of March. Keri started off on 1 March with the defence of thesis entitled Biochemical and Structural Studies on PrfA, the Transcriptional Regulator of Virulence in Listeria monocytogenes. Unfortunately, Keri will be leaving the lab in the beginning of May to start her po...

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