heroin.org.uk
Dopamine: the pleasure and the pain
http://heroin.org.uk/dopamine
Pain, Itself, Elicits Pain Relief,. And Does So Through "Reward" Pathway. Researchers have long known that the body can activate its own form of pain relief in response to painful stimuli. Now, UC San Francisco investigators have determined that, in rats, this long-lasting relief is produced by the brain's "reward" pathway - the neural circuitry activated by drugs of abuse. In their study, published in the August 15 issue of Journal of Neuroscience. We're showing that something aversive - exposure to a p...
erythroxylum-coca.com
Coca, cocaine and crack
http://www.erythroxylum-coca.com/refs/index.html
Coca, Cocaine and Crack. AMPA/kainate, NMDA, and mGlu5 receptors. Cocaine/dopamine d2/mu opioid connection. Cocaine hydrochloride vs crack. Crack smoking and Brillo pads. Gene expression profiles: heroin vs cocaine. Noradrenaline/dopamine vs serotonin releasers. Perniosis, pulp atrophy and 'parrot-beaked' clawing. TAC (tetracaine, adrenaline and cocaine). Viral transduction of cocaine hydrolase. Coca, cocaine and crack info. Human Rights and the Drug War. Google Cocaine and Crack Directory.
opioids.com
Kappa opioid antagonists as antidepressants : norbinaltorphimine, 5'-guanidinonaltrindole (GNTI) and 5'-acetamidinoethylnaltrindole (ANTI)
http://www.opioids.com/norbinaltorphimine/antidepressant.html
Antidepressant-like effects of kappa-opioid. Receptor antagonists in the forced swim test in rats. Mague SD, Pliakas AM, Todtenkopf MS,. Tomasiewicz HC, Zhang Y, Stevens WC Jr,. Jones RM, Portoghese PS, Carlezon WA Jr. Behavioral Genetics Laboratory,. Department of Psychiatry,. Harvard Medical School,. McLean Hospital, Belmont,. Massachusetts 02478, USA. J Pharmacol Exp Ther. Endomorphins 1 and 2. The Pleasures of Opium. Opioids, depression and learned helplessness. Critique of Huxley's Brave New World.
