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EpiGenSys

EpiGenSys project page

http://www.epigensys.org/

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DKFZ Heidelberg

Tobias Reber

Im Neuen●●●●●●●●Feld 280

Hei●●●erg , 69120

DE

49.6●●●●2356
49.6●●●●2399
t.●●●●●@dkfz.de

View this contact

DKFZ Heidelberg

Tobias Reber

Im Neuen●●●●●●●●Feld 280

Hei●●●erg , 69120

DE

49.6●●●●2356
49.6●●●●2399
t.●●●●●@dkfz.de

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EpiGenSys | epigensys.org Reviews
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EpiGenSys project page
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EpiGenSys | epigensys.org Reviews

https://epigensys.org

EpiGenSys project page

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epigensys.org epigensys.org
1

Epi-Gen-Sys

https://www.epigensys.org/wp4.html

System Biological Determination of the Epigenomic Structure – Function Relation. Ndash; EpiGenSys –. Simulations of nucleosomal, chromatin fiber and chromosome architecture and dynamics. TA Knoch/F. Grosveld. Kepper, N., Ettig, R., Stehr, R., Wedemann, G. and Rippe, K. (2011). Force spectroscopy of chromatin fibers: extracting energetics and structural information from Monte Carlo simulations,.

2

EpiGenSys

https://www.epigensys.org/publications.html

System Biological Determination of the Epigenomic Structure – Function Relation. Ndash; EpiGenSys –. Pham, T.-H., Minderjahn, J., Schmidl, C., Hoffmeister, H., Schmidhofer, S., Chen, W., Längst, G., Benner, C. and Rehli, M. (2013). Mechanisms of in-vivo binding site selection of the hematopoietic master transcription factor PU.1. Published online 26 Feb 2013. Published online 23 March 2013. Nat Struct. Mol. Biol. Mol Cell. Biol. Kolovos, P., Knoch, T. A., Grosveld, F. G., Cook, P....Ettig, R., Kepper...

3

Epi-Gen-Sys

https://www.epigensys.org/wp5.html

System Biological Determination of the Epigenomic Structure – Function Relation. Ndash; EpiGenSys –. System biological result integration via the GLOBE 3D Genome Platform. Here we show some movies which illustrate the capabilities of the GLOBE 3D Genome Platform:. Overview Movie 1 (95 MB). Overview Movie 2 (200 MB). Overview Movie 3 (221 MB). Gene Duplication Movie (15 MB). DNA Clone Movie (119 MB). DNA FISH/Duplication Movie (16 MB ). TA Knoch/F. Grosveld.

4

Epi-Gen-Sys

https://www.epigensys.org/wp3.html

System Biological Determination of the Epigenomic Structure – Function Relation. Ndash; EpiGenSys –. In WP3 "transcriptional structure relationship" we will focus on the determination of transcription rates of selected loci by qRT-PCR, DNA and RNA FISH using intronic probes and high-resolution laser-scanning and single molecule imaging with advanced image analysis tools. Transcription-dependent changes of active and inactive loci as well as rapid synchronous transcription alteration against the uncha...

5

Epi-Gen-Sys

https://www.epigensys.org/wp.html

System Biological Determination of the Epigenomic Structure – Function Relation. Ndash; EpiGenSys –. Our systems biology approach will involve 5 work packages. WP1: Nucleosomal association changes. WP2: Intra/inter chromosomal architecture. WP3: Transcriptional structure relationship. WP4: Simulations of nucleosomal, chromatin fiber and chromosome architecture and dynamics. WP5: System biological result integration via the GLOBE 3D Genome Platform.

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System Biological Determination of the Epigenomic Structure – Function Relation. Ndash; EpiGenSys –. July 29, 2013, Oxford, UK – Public lecture: Nucleosome positioning during embryonic stem cell development by Karsten Rippe. July 29-31 2013, Oxford, UK – From nucleosome positions to chromatin folding organized by Peter Cook. 3-5 July 2012, Oxford, UK – Chromatin structure-function relationships: Linking exeriments and models, Organizers: Argyrios Papantonis and Peter Cook.

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