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Esashi Lab – investigating genome stability control

The Esashi group aims to understand how proliferating human cells protect their genomic DNA against various environmental stresses (e.g., radiation, genotoxic drugs) as well as those arising from normal processes of cell growth (e.g., replication, transcription). We are particularly interested in homologous recombination (HR), which provides a powerful mechanism to repair broken DNA faithfully and…

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Esashi Lab – investigating genome stability control | esashilab.wordpress.com Reviews

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The Esashi group aims to understand how proliferating human cells protect their genomic DNA against various environmental stresses (e.g., radiation, genotoxic drugs) as well as those arising from normal processes of cell growth (e.g., replication, transcription). We are particularly interested in homologous recombination (HR), which provides a powerful mechanism to repair broken DNA faithfully and…

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Esashi Lab – investigating genome stability control | esashilab.wordpress.com Reviews

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The Esashi group aims to understand how proliferating human cells protect their genomic DNA against various environmental stresses (e.g., radiation, genotoxic drugs) as well as those arising from normal processes of cell growth (e.g., replication, transcription). We are particularly interested in homologous recombination (HR), which provides a powerful mechanism to repair broken DNA faithfully and…

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Publication – Esashi Lab

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Investigating genome stability control. Orpinell M, Grauffel C, Scheer E, Garnier JM, Ye T, Chavant V, Joint M, Esashi F. Dejaegere A, Gonczy P, Tora L. KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification. Nat. Commun. 2016 Oct 31. DOI: 10.1038/ncomms13227. Moudry P, Watanabe K, Wolanin KM, Bartkova J, Wassing IE. Watanabe S, Strauss R, Troelsgaard Pedersen R, Oestergaard VH, Lisby M, Andújar-Sánchez M, Maya-Mendoza A, Esashi F. Pefani DE, Latusek R, ...

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Josh leaving – Esashi Lab

https://esashilab.wordpress.com/2016/08/12/josh-leaving

Investigating genome stability control. August 12, 2016. September 25, 2016. We are really sad that Josh is leaving after a very productive 8-week summer project… Well done Josh and all the best for future! Regulation of Plk4 by acetylation. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). You are commenting using your WordPress.com account. ( Log Out. You are commenting using your Twitter account. ( Log Out.

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Links – Esashi Lab

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Investigating genome stability control. Sir William Dunn School of Pathology. Departmental Prize Studentship Competition. The University of Oxford Doctoral Training Centre. Wellcome Trust DPhil in Chromosome and Developmental Biology. Lab retreat at Dinefwr, Llandeilo (21st-24th Jan 2017). January 28, 2017. January 18, 2017. Welcome back, Lucia! January 9, 2017. X’mas gathering at Fumiko’s place. December 17, 2016. Congratulations, Kirsten & Federico! October 5, 2016. Sir William Dunn School of Pathology.

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X’mas gathering at Fumiko’s place – Esashi Lab

https://esashilab.wordpress.com/2016/12/17/xmas-gathering-at-fumikos-place

Investigating genome stability control. X’mas gathering at Fumiko’s place. December 17, 2016. December 29, 2016. Thanks everyone for bringing delicious food to share! Congratulations, Kirsten & Federico! Welcome back, Lucia! Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). You are commenting using your WordPress.com account. ( Log Out. You are commenting using your Twitter account. ( Log Out. January 28, 2017.

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About Fumiko Esashi – Esashi Lab

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Investigating genome stability control. Wellcome Trust Senior Research Fellow. Associate Professor at the University of Oxford. Frontiers in Cell and Dev. Biol. 2001-2007 Cancer Research UK, London Research Institute. Postdoctoral research with Dr Stephen C. West. Project: The role of familial breast cancer gene BRCA2 in genome stability. 1995-2001 Kyoto University, Department of Biophysics, Japan. MSc, Ph.D. and postdoctoral research with Prof. Mitsuhiro Yanagida. January 28, 2017. January 18, 2017.

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Group | DUSHEK LAB

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Laboratory for molecular immunology. Enas Abu Shah (Post-doctoral fellow, joint with. John Nguyen (D.Phil student). Nicola Coker Gordon (D.Phil student). Citlali Solis Salas (D.Phil student, joint with. Federico Paoletti (D.Phil student, joint with. Mikhail Kutuzov (Post-doctoral fellow). Marcus Bridge (Laboratory manager). We are always interested in hearing from excellent scientists interested in joining the laboratory. Left to right: Federico, Enas, Philipp, John, Nicola, James, Citlali, Omer.

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Fumiko Esashi | Sir William Dunn School of Pathology

http://www.path.ox.ac.uk/content/fumiko-esashi

Skip to main content. Cancer and Genome stability. Development and stem cells. RNA and Gene expression. Anton van der Merwe. Genome Engineering Oxford (GEO). Surface Plasmon Resonance Facility. The James Martin Stem Cell Facility. Departmental Prize Studentship Competition. Fees, funding and Colleges. This week at Dunn school. The Norman Heatley Lecture. Final year honours schools in Infection and Immunity and Molecular Medicine. Matthew Freeman, Head of Department. The Discovery of Penicillin. Yata, K, ...

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Esashi Lab – investigating genome stability control

Investigating genome stability control. Our previous studies revealed several unexpected regulatory mechanisms for HR, whereby the key HR proteins Rad51, BRCA2 and PALB2 are regulated spatio-temporally by central cell cycle kinases such as cyclin-dependent kinases (CDKs) and polo-like kinase 1 (Plk1) in proliferating human cells. The group continues to tackle challenging questions regarding the regulation of HR using a multidisciplinary approach, including protein biochemistry, molecular and cellular...

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