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Rebekah L. Rogers: Evolutionary Genetics

The Rogers lab studies evolution of genome structure. We explore the ways that complex mutations like duplications, deletions, rearrangements, and retrogenes can create new genetic material. We study how these new mutations are important for adaptation. We are currently working on projects in. Mammoths, and Frogs. This multi-organism approach can help us understand when and why complex mutations are important for organism fitness. We are actively recruiting postdocs and graduate students.

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Rebekah L. Rogers: Evolutionary Genetics | evolscientist.com Reviews

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The Rogers lab studies evolution of genome structure. We explore the ways that complex mutations like duplications, deletions, rearrangements, and retrogenes can create new genetic material. We study how these new mutations are important for adaptation. We are currently working on projects in. Mammoths, and Frogs. This multi-organism approach can help us understand when and why complex mutations are important for organism fitness. We are actively recruiting postdocs and graduate students.

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1 Genetic novelty

2 evolutionary genetics

3 evolution

4 Rebekah L. Rogers

5 RL Rogers

6 Rogers RL

7 Rebekah Rogers

8 new genes

9 genetics

10 Drosophila

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Rebekah L. Rogers: Evolutionary Genetics | evolscientist.com Reviews

https://evolscientist.com

The Rogers lab studies evolution of genome structure. We explore the ways that complex mutations like duplications, deletions, rearrangements, and retrogenes can create new genetic material. We study how these new mutations are important for adaptation. We are currently working on projects in. Mammoths, and Frogs. This multi-organism approach can help us understand when and why complex mutations are important for organism fitness. We are actively recruiting postdocs and graduate students.

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evolscientist.com

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Rebekah L. Rogers: Evolutionary Genetics

http://www.evolscientist.com/Chims.html

Chimeric genes arise when portions of two existing coding sequences combine to produce a single open reading frame. These new genes can provide a significant source of genetic novelty and are often associated with selective sweeps. Figure 1. Mechanisms of Chimeric Gene Formation. A. Large loop mismatch repair. B. Replication Slippage. C. Ectopic Recombination. D. Retrotransposition. Our current work in. Figure 2. Selective Sweep on. Surveyed to date, but has not been found in strains of. Also show statis...

2

Rebekah L. Rogers: Evolutionary Genetics

http://www.evolscientist.com/FastQDownload.html

Fastq Files for D. yakuba. Due to IT issues with the UCI public data servers, fastq files have been moved. Files may be accessed here:. We were recently notified that the NCBI data processing pipeline for the SRA has modified the .bam files for our D. yakuba.

3

Rebekah L. Rogers: Evolutionary Genetics

http://www.evolscientist.com/CNV.html

Duplications are a fundamental source of genetic novelty and genomic complexity and their prevalance in natural populations is expected to influence evolutionary trajectories. We have surveyed natural populations of. To assess the number and types of gene duplciatons present among standing variation as well as the impacts that duplicates can have in adaptive evolution. Figure 1. Locations of duplications identified in 20 strains of. We have generated paired end Illumina sequencing reads for 20 strains of.

4

Rebekah L. Rogers: Publications

http://www.evolscientist.com/Pubs.html

And M Slatkin. 2015. Genomic disintegration in woolly mammoths on Wrangel island. ArXiv preprint. 2015 Chromosomal rearrangments as barriers to genetic homogenization between archaic and modern humans. Accepted. Moluecular Biology and Evolution. ArXiv preprint. Early online from MBE. JM Cridland, L Shao, TT Hu, P. Andolfatto, and KR Thornton. 2015. Tandem duplications and the limits of natural selection in Drosophila yakuba. Group G3:Genes, Genomes, Genetics. And DL Hartl. 2012. Pontaroli, AC, RL Rogers.

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Rebekah L. Rogers: Evolutionary Genetics

http://www.evolscientist.com/NeanderthalStruct.html

Genome structure variants identified using archaic human genomes. A zip archive of structural variant calls identified using the sequenced genomes of archaic humans is available here. Manuscripts using genome structure calls prior to publication must. Cite Rogers 2015 "Chromosomal rearrangements as barriers to genetic homogenization between modern and archaic humans" available from ArXiv. The data set may not be used prior to publication without preprint citation under any circumstances.

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Rebekah L. Rogers: Evolutionary Genetics

The Rogers lab studies evolution of genome structure. We explore the ways that complex mutations like duplications, deletions, rearrangements, and retrogenes can create new genetic material. We study how these new mutations are important for adaptation. We are currently working on projects in. Mammoths, and Frogs. This multi-organism approach can help us understand when and why complex mutations are important for organism fitness. We are actively recruiting postdocs and graduate students.

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