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ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. CD40 is a major regulatory receptor in the immune system. There is a wealth of literature supporting the involvement of the CD40 pathway in the pathophysiology of a variety of chronic inflammatory / autoimmune diseases. FF Pharma company profile. FF Pharma is a privately owned biopharmaceutical company, which was founded in October 2012. The com...

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ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. CD40 is a major regulatory receptor in the immune system. There is a wealth of literature supporting the involvement of the CD40 pathway in the pathophysiology of a variety of chronic inflammatory / autoimmune diseases. FF Pharma company profile. FF Pharma is a privately owned biopharmaceutical company, which was founded in October 2012. The com...

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ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. CD40 is a major regulatory receptor in the immune system. There is a wealth of literature supporting the involvement of the CD40 pathway in the pathophysiology of a variety of chronic inflammatory / autoimmune diseases. FF Pharma company profile. FF Pharma is a privately owned biopharmaceutical company, which was founded in October 2012. The com...

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FFPharma.com - Press Releases

http://www.ffpharma.com/2014/index.php/news-more/press-releases

FF Pharmaceuticals initiates Phase II Pilot Studies in PBC and CD with anti-CD40 Monoclonal Antibody. FF Pharmaceuticals closes Series A financing round. Postal address: Yalelaan 46 - 3584 CM Utrecht. Visiting address: Yalelaan 62 - 3584 CM Utrecht. Agoralaan A bis - B-3590 Diepenbeek.

2

FFPharma.com - CD40

http://www.ffpharma.com/2014/index.php/science-and-medicine/cd40

CD40 also plays a role in the efficient activation of T-cells by antigen presenting cells (APCs). The physiological ligand for CD40 is CD154. T-cell CD154 binding to CD40 on immature dendritic cells (DC) causes DC maturation, increases expression of the co-stimulatory molecules CD80 and CD86 on DCs, and causes increased production of cytokines, including TNF-α, interleukin 8 (IL-8) and IL-12, to be released from APCs. Postal address: Yalelaan 46 - 3584 CM Utrecht. Agoralaan A bis - B-3590 Diepenbeek.

3

FFPharma.com - Primary Biliary Cirrhosis

http://www.ffpharma.com/2014/index.php/science-and-medicine/primary-biliary-cirrhosis

Postal address: Yalelaan 46 - 3584 CM Utrecht. Visiting address: Yalelaan 62 - 3584 CM Utrecht. Agoralaan A bis - B-3590 Diepenbeek.

4

FFPharma.com - Crohn’s Disease

http://www.ffpharma.com/2014/index.php/science-and-medicine/crohn-s-disease

Ch5D12, the precursor molecule of FFP104 was already tested in a clinical study with subjects suffering from CD. 18 CD patients were enrolled into 4 dose cohorts. A significant decrease of the CDAI score was observed after a single dose of ch5D12. Details of this ch5D12 study can be found in the Kasran paper under NEWS AND MORE READING ROOM. Postal address: Yalelaan 46 - 3584 CM Utrecht. Visiting address: Yalelaan 62 - 3584 CM Utrecht. Agoralaan A bis - B-3590 Diepenbeek.

5

FFPharma.com - Therapeutic Antibodies

http://www.ffpharma.com/2014/index.php/science-and-medicine/therapeutic-antibodies

Monoclonal antibodies are exciting molecules having made a dramatic transformation from scientific tools to powerful human therapeutics. Having been in the doldrums for almost three decades, they are now living up to their promise as therapeutic drugs. At present, more than 30 therapeutic monoclonal antibodies are marketed in the United States and Europe in a variety of indications. Postal address: Yalelaan 46 - 3584 CM Utrecht. Visiting address: Yalelaan 62 - 3584 CM Utrecht.

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ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. ANTI-CD40 ANTIBODY THERAPY FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES. CD40 is a major regulatory receptor in the immune system. There is a wealth of literature supporting the involvement of the CD40 pathway in the pathophysiology of a variety of chronic inflammatory / autoimmune diseases. FF Pharma company profile. FF Pharma is a privately owned biopharmaceutical company, which was founded in October 2012. The com...

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