flupol.eu

Flupol

FLUPOL : Host-specific Variants of the Influenza Virus Replication Machinery. 1 973 450 €. Summary. We aim to understand how the influenza virus replication machinery adapts during interspecies transmission and use this knowledge to provide new tools to combat potentially pandemic influenza outbreaks. 1 Prof. Rob Ruigrok, Unit of Virus Host Cell Interactions [UVHCI], UMR 5233 UJF-EMBL-CNRS. 2 Dr Vincent Lotteau, INSERM Unit 503, Lyon, France. 5 demonstrates how the last twenty residues unfold to permit b...

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FLUPOL : Host-specific Variants of the Influenza Virus Replication Machinery. 1 973 450 €. Summary. We aim to understand how the influenza virus replication machinery adapts during interspecies transmission and use this knowledge to provide new tools to combat potentially pandemic influenza outbreaks. 1 Prof. Rob Ruigrok, Unit of Virus Host Cell Interactions [UVHCI], UMR 5233 UJF-EMBL-CNRS. 2 Dr Vincent Lotteau, INSERM Unit 503, Lyon, France. 5 demonstrates how the last twenty residues unfold to permit b...

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3 contract no

4 ec contribution

5 instrument

6 fp6 strep

7 coordinator

8 stephen cusack

9 problem

10 expected results

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Flupol | flupol.eu Reviews

https://flupol.eu

FLUPOL : Host-specific Variants of the Influenza Virus Replication Machinery. 1 973 450 €. Summary. We aim to understand how the influenza virus replication machinery adapts during interspecies transmission and use this knowledge to provide new tools to combat potentially pandemic influenza outbreaks. 1 Prof. Rob Ruigrok, Unit of Virus Host Cell Interactions [UVHCI], UMR 5233 UJF-EMBL-CNRS. 2 Dr Vincent Lotteau, INSERM Unit 503, Lyon, France. 5 demonstrates how the last twenty residues unfold to permit b...

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flupharm.eu

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The 2009 H1N1 influenza A virus pandemic and the ongoing threat of highly pathogenic H5N1 avian influenza strains have focused attention worldwide on the urgent need for new options of effective anti-influenza drugs, when the public is not protected by vaccination. The need is pressing since several circulating influenza strains are resistant to the currently stockpiled neuraminidase inhibitors. If successful, FLUPHARM. Will provide new opportunities to treat both seasonal and pandemic flu, including the...

flupharm.eu

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http://flupharm.eu/concept

ANTI-INFLUENZA DRUGS TARGETING THE POLYMERASE. There are two approaches to inhibiting viral replication. Either by directly targeting viral proteins or by targeting the host proteins essential for the viral life cycle. In previous work within the EU funded FLUPOL. Project, EMBL and UJF have identified and determined the atomic structure of two key domains of the polymerase: The mRNA cap-binding domain in the PB2 subunit. And the endonuclease-active site in the PA subunit. Based on the atomic structures, ...

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FLUPOL : Host-specific Variants of the Influenza Virus Replication Machinery. 1 973 450 €. Summary. We aim to understand how the influenza virus replication machinery adapts during interspecies transmission and use this knowledge to provide new tools to combat potentially pandemic influenza outbreaks. 1 Prof. Rob Ruigrok, Unit of Virus Host Cell Interactions [UVHCI], UMR 5233 UJF-EMBL-CNRS. 2 Dr Vincent Lotteau, INSERM Unit 503, Lyon, France. 5 demonstrates how the last twenty residues unfold to permit b...

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