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The Furlong Laboratory – Developmental Regulatory Genomics

Dissecting fundamental principles of transcriptional regulation, and how it drives cell fate decisions during development, focusing on the organisational and functional properties of the genome.

http://furlonglab.embl.de/

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The Furlong Laboratory – Developmental Regulatory Genomics | furlonglab.embl.de Reviews
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Dissecting fundamental principles of transcriptional regulation, and how it drives cell fate decisions during development, focusing on the organisational and functional properties of the genome.
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1 transcription
2 transcriptional networks
3 muscle
4 development
5 regulatory network
6 CoCo
7 developmental networks
8 ChIP-on-chip
9 ChIP-chip
10 Chromatin Immunoprecipitation
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The Furlong Laboratory – Developmental Regulatory Genomics | furlonglab.embl.de Reviews

https://furlonglab.embl.de

Dissecting fundamental principles of transcriptional regulation, and how it drives cell fate decisions during development, focusing on the organisational and functional properties of the genome.

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1

Furlong Laboratory • People

http://furlonglab.embl.de/people

Group Leader and Head of Genome Biology Unit at EMBL. Software Developer, Bioinformatician and Head of Genome Biology Computational Support. Janus S. Jackobsen.

2

Furlong Laboratory • Publications

http://furlonglab.embl.de/publications

All supplementary data is available in the Download section. Yad Ghavi-Helm, Felix A. Klein*, Tibor Pakozdi*, Lucia Ciglar, Daan Noordermeer, Wolfgang Huber and Eileen E.M. Furlong. Enhancer loops appear stable during development and are associated with paused polymerase. Lucia Ciglar, Charles Girardot, Bartek Wilczynski, Martina Braun and Eileen E.M. Furlong. Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis. Jan 15, 2014; 28 (2). Tseng, Q.,...

3

Furlong Laboratory • Data

http://furlonglab.embl.de/data

Supplementary information about lab publications can be found in the Data downloads. Genome browser featuring all 4C-seq view points published in Ghavi-Helm et al. Allows you to search our ChIP-on-chip data for transcription factor binding in the vicinity of your gene of interest. The affect of a loss of function mutation on the expression of a gene can be visualised as either a histogram or a spline.

4

Furlong Laboratory • Methods

http://furlonglab.embl.de/methods

The following protocols are available for download:. ChIP-on-chip protocol optimized for Drosophila. We have developed a number of tools to facilitate genomic experiments in Drosophila. CoCo – ChIP-on-chip online. Automated target gene assignment from ChIP-on-chip data.

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Home Page of Bartek Wilczynski

http://bartek.rezolwenta.eu.org/notmyblog/index.html

Homepage of Bartek Wilczyński. I'm interested in computational biology approaches to gene expression regulation. This falls into two main areas:. Role of chromatin state in transcription regulation. Computational modeling of transcriptional regulation in the context of chromatin dynamics. Modeling gene regulatory networks. Many regulatory interactions depend on specific sequence signals like cis-regulatory elements, microRNA sequences or amino-acid sequence motifs in proteins. Understanding the preci...

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Home Page of Bartek Wilczynski

http://bartek.rezolwenta.eu.org/notmyblog/pubs.html

Homepage of Bartek Wilczyński. A specialized histone H1 variant is required for adaptive responses to complex abiotic stress and related DNA methylation in Arabidopsis. Plant Physiology September 2015 pp.00493.2015. Krisztian Buza, Bartek Wilczynski, and Norbert Dojer,. RECORD: Reference-Assisted Genome Assembly for Closely Related Genomes. International Journal of Genomics, May 2015. Y Wei, S. Mondal, R. Mouawad, B. Wilczynski, R.W. Henry, D. Arnosti. G3 May 20, 2015 g3.115.019166. BMC Systems Biology, ...

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Jacob Degner's homepage

https://sites.google.com/site/jfdegner

I am a Senior Scientist at the global pharmaceutical company, AbbVie. I am working within the Pharmacogenetics and Pharmacogenomics division where I apply my academic training in bioinformatics, statistics, and genetics to understanding the genetic basis of inter-individual variation in drug response across a wide range of therapeutic areas. Previous education and work. I grew up on Chicago's northwest side. And developed an early interest in biological research working in the Department of Zoology.

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CardioSignal WebTools

http://www.cardiosignal.org/links/links.html

The heart of creatures is the foundation of life, the Prince of all, the sun of their microcosm, from where all vigor and strength does flow. - William Harvey, De Motu Cordis, 1628. NAR Database Summary Paper Category List. Regulatory Element Database for. CArdiac Regulatory INteraction database (CARIN). MOODS: Motif Occurrence Detection Suite. Stark Lab Deciphering the transcriptional cis-regulatory code. The Furlong lab: Transcriptional networks. Young Lab, MIT. Stam Lab, university of washington.

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The Furlong Laboratory – Developmental Regulatory Genomics

September 1, 2017. Jelena, Tibor and Raquel's paper: Enhancers function as PcG dependent silencers and viceversa ncbi.nlm.nih.gov/pubmed/28381411. September 1, 2017. Congrats Yad @yad ghavi. On your new lab ghavihelmlab.com. Powered by The Furlong Laboratory.

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