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Quantification of population benefit of biomarkers – Thomas L Vaughan MD, MPH

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Thomas L Vaughan MD, MPH. Temporal and spacial evolution of somatic chromosomal alterations. CDKN2A Germline Variations Associated with Risk of Barrett’s and Esophageal Adenocaricnoma →. Quantification of population benefit of biomarkers. July 23, 2015. BMC Med Inform Decis Mak. 2014 Mar 6;14:15. doi: 10.1186/1472-6947-14-15. Quantification of population benefit in evaluation of biomarkers: practical implications for disease detection and prevention. Li X, Blount PL, Reid BJ, Vaughan TL. RESULTS: We prop...

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Thomas L Vaughan MD, MPH – Page 2 – Research & Publications

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Thomas L Vaughan MD, MPH. Newer posts →. Precision Prevention of Esophageal Adenocarcinoma. July 23, 2015. Nat Rev Gastroenterol Hepatol. 2015 Apr;12:243-248. Precision prevention of oesophageal adenocarcinoma. Https:/ en.wikipedia.org/wiki/Charles Joseph Minard. CDKN2A Germline Variations Associated with Risk of Barrett’s and Esophageal Adenocaricnoma. July 23, 2015. This study was led by Matt Buas, post-doctoral fellow in my group. Carcinogenesis. 2014 Dec;35(12):2740-7. July 23, 2015. Li X, Blount PL,...

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Research Interests – Thomas L Vaughan MD, MPH

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Thomas L Vaughan MD, MPH. Over the past 40 years, the incidence of adenocarcinoma of the esophagus among white males in the US has increased 10-fold. Rapid increases among females and African American males also have been observed. This rapidly fatal cancer is becoming increasingly common in parts of western Europe as well. Fred Hutchinson Cancer Center. University of Washington Epidemiology Department. Other Links of Interest. Recent Literature on Esophageal Cancer. 2016 - Thomas L Vaughan MD, MPH.

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Temporal and spacial evolution of somatic chromosomal alterations – Thomas L Vaughan MD, MPH

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Thomas L Vaughan MD, MPH. Obesity Genetic Susceptibility Linked with Esophageal Adenocarcinoma Risk in JNCI paper. Quantification of population benefit of biomarkers →. Temporal and spacial evolution of somatic chromosomal alterations. July 23, 2015. Xiaohong Li, the head statistician on our Program Project, led this multidisciplinary effort to identify the magnitude and timing of somatic chromosomal alterations during neoplastic progression to esophageal adenocarcinoma. Blount PL, Reid BJ. All cancers a...

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Publications – Thomas L Vaughan MD, MPH

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Thomas L Vaughan MD, MPH. Click here for an automated PubMed search. For publications I have authored. Click here for my Google Scholars page. Below is a more complete listing that also includes submitted manuscripts, book chapters, etc. (* indicates paper led by my student or post-doc.). Updated 18 July 2016). Voltzke KJ, Lee Y-CA, Zhang ZF, Zevallow JP, Yu, GP, Winn DM, Vaughan TL. Huang G, Zeng Y, Zeng YX, Adami HO. Development of a population-based cancer case-control study in southern China. Role of...

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CDKN2A Germline Variations Associated with Risk of Barrett’s and Esophageal Adenocaricnoma – Thomas L Vaughan MD, MPH

http://res.tlvcloud.org/2015/02/cdkn2a-germline-variations-associated-with-risk-of-barretts-and-esophageal-adenocaricnoma

Thomas L Vaughan MD, MPH. Quantification of population benefit of biomarkers. Precision Prevention of Esophageal Adenocarcinoma →. CDKN2A Germline Variations Associated with Risk of Barrett’s and Esophageal Adenocaricnoma. July 23, 2015. This study was led by Matt Buas, post-doctoral fellow in my group. Carcinogenesis. 2014 Dec;35(12):2740-7. Integrative post-genome-wide association analysis of CDKN2A and TP53 SNPs and risk of esophageal adenocarcinoma. Quantification of population benefit of biomarkers.

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Risk of esophageal adenocarcinoma decreases with increasing height – Thomas L Vaughan MD, MPH

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Thomas L Vaughan MD, MPH. Role of genetic susceptibility in Barrett’s and esophageal adenocarcinoma. Obesity Genetic Susceptibility Linked with Esophageal Adenocarcinoma Risk in JNCI paper →. Risk of esophageal adenocarcinoma decreases with increasing height. July 23, 2015. L 2014 Feb 12. pii: S1542-3565(14)00199-2. doi: 10.1016/j.cgh.2014.01.039. [Epub ahead of print]. Risk of Esophageal Adenocarcinoma Decreases with Height, Based on Consortium Analysis and Confirmed by Mendelian Randomization. Other Li...

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Photography – Thomas L Vaughan MD, MPH

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Thomas L Vaughan MD, MPH. I enjoy photography in my spare time. Click the image to visit my gallery. Fred Hutchinson Cancer Center. University of Washington Epidemiology Department. Other Links of Interest. Recent Literature on Esophageal Cancer. Oxygen can impair cancer immunotherapy in mice. Uncovering a new principle in chemotherapy resistance in breast cancer. International collaboration to create new cancer models to accelerate research. 2016 - Thomas L Vaughan MD, MPH. Proudly powered by WordPress.

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Precision Prevention of Esophageal Adenocarcinoma – Thomas L Vaughan MD, MPH

http://res.tlvcloud.org/2015/05/precision-prevention-of-esophageal-adenocarcinoma

Thomas L Vaughan MD, MPH. CDKN2A Germline Variations Associated with Risk of Barrett’s and Esophageal Adenocaricnoma. Reflux interacts with FOXP1 genotype in predisposing to Barrett’s esophagus →. Precision Prevention of Esophageal Adenocarcinoma. July 23, 2015. Nat Rev Gastroenterol Hepatol. 2015 Apr;12:243-248. Precision prevention of oesophageal adenocarcinoma. Https:/ en.wikipedia.org/wiki/Charles Joseph Minard. Reflux interacts with FOXP1 genotype in predisposing to Barrett’s esophagus →. Newly laun...