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Evolutionary Bioinformatics Laboratory

Tuesday, August 27, 2013. The roots of genetics lie on the peptide bond! This changes the focus of molecular biology, from replicators and genetics to molecular dynamics, emergence and the chemistries of function. Caetano-Anollés G, Wang M, Caetano-Anollés D (2013) Structural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibility. PLoS ONE 8(8): e72225. doi:10.1371/journal.pone.0072225. Thursday, June 6, 2013. The origin of viruses revealed!

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Evolutionary Bioinformatics Laboratory | gcalab.blogspot.com Reviews
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Tuesday, August 27, 2013. The roots of genetics lie on the peptide bond! This changes the focus of molecular biology, from replicators and genetics to molecular dynamics, emergence and the chemistries of function. Caetano-Anollés G, Wang M, Caetano-Anollés D (2013) Structural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibility. PLoS ONE 8(8): e72225. doi:10.1371/journal.pone.0072225. Thursday, June 6, 2013. The origin of viruses revealed!
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Evolutionary Bioinformatics Laboratory | gcalab.blogspot.com Reviews

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Tuesday, August 27, 2013. The roots of genetics lie on the peptide bond! This changes the focus of molecular biology, from replicators and genetics to molecular dynamics, emergence and the chemistries of function. Caetano-Anollés G, Wang M, Caetano-Anollés D (2013) Structural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibility. PLoS ONE 8(8): e72225. doi:10.1371/journal.pone.0072225. Thursday, June 6, 2013. The origin of viruses revealed!

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Evolutionary Bioinformatics Laboratory: The origin of viruses revealed!

http://www.gcalab.blogspot.com/2013/06/the-origin-of-viruses-revealed.html

Thursday, June 6, 2013. The origin of viruses revealed! Nasir et al. (2012) Viral evolution: Primordial cellular origins and late adaptation to parasitism. Mob. Genet. Elements 2(5): 247-252. Nasir et al. (2012) Giant viruses coexisted with the cellular ancestors and represent a distinct supergroup along with superkingdoms Archaea, Bacteria and Eukarya. BMC Evol. Biol. 12: 156. Subscribe to: Post Comments (Atom). Simple template. Powered by Blogger.

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Evolutionary Bioinformatics Laboratory: Origins of translation and cellular life

http://www.gcalab.blogspot.com/2011/08/origins-of-translation-and-cellular.html

Monday, August 22, 2011. Origins of translation and cellular life. A paper by Derek Caetano-Anollés, Kyung Mo Kim, Jay E. Mittenthal and Gustavo Caetano-Anollés, " P. Roteome evolution and the metabolic origins of translation and cellular life ",. Was recently published in the Journal of Molecular Evolution. 72: 14-32, 2011. The paper describes phylogenomic efforts to unravel the history of the translation apparatus using information in the structure of protein domains at the fold family level of structu...

3

Evolutionary Bioinformatics Laboratory: The catalytic origin of modern molecular functions inferred from phylogenomic analysis of ontological data

http://www.gcalab.blogspot.com/2010/06/catalytic-origin-of-modern-molecular.html

Monday, June 28, 2010. The catalytic origin of modern molecular functions inferred from phylogenomic analysis of ontological data. A paper by Kyung Mo Kim and Gustavo Caetano-Anollés appeared published today in Molecular Biology and Evolution. 27: 1710-1733, 2010) that describes the origin and evolution of molecular functions in biology. And the progressive development of protein biosynthetic machinery, transport systems, and regulation. Gesteland, R.F., Atkins, J.F. 1993. The RNA wor...S, G, Kim, H....

4

Evolutionary Bioinformatics Laboratory: The origin of the ribosome is in mechanics, not protein synthesis

http://www.gcalab.blogspot.com/2013/06/the-origin-of-ribosome-is-in-mechanics.html

Thursday, June 6, 2013. The origin of the ribosome is in mechanics, not protein synthesis. This changes the perception we have of the rise of modern biochemistry and prompts further analysis of the emergence of biological complexity in an ever-expanding coevolving world of macromolecules (Caetano-Anollés and Seufferheld, J. Mol. Microbiol. Biotechnol. 23 (1-2): 152-177, 2013. Subscribe to: Post Comments (Atom). Simple template. Powered by Blogger.

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Evolutionary Bioinformatics Laboratory: The roots of genetics lie on the peptide bond!

http://www.gcalab.blogspot.com/2013/08/the-roots-of-genetics-lie-on-peptide.html

Tuesday, August 27, 2013. The roots of genetics lie on the peptide bond! This changes the focus of molecular biology, from replicators and genetics to molecular dynamics, emergence and the chemistries of function. Caetano-Anollés G, Wang M, Caetano-Anollés D (2013) Structural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibility. PLoS ONE 8(8): e72225. doi:10.1371/journal.pone.0072225. December 13, 2013 at 5:37 AM. June 20, 2014 at 2:28 AM.

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Evolutionary Bioinformatics Laboratory

Tuesday, August 27, 2013. The roots of genetics lie on the peptide bond! This changes the focus of molecular biology, from replicators and genetics to molecular dynamics, emergence and the chemistries of function. Caetano-Anollés G, Wang M, Caetano-Anollés D (2013) Structural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibility. PLoS ONE 8(8): e72225. doi:10.1371/journal.pone.0072225. Thursday, June 6, 2013. The origin of viruses revealed!

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