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Simulation and Reconstruction of 3-D Epithelial Structure.3-D Structural Histology.

Simulation and Reconstruction of 3-D Epithelial Structure. 3-D Structural Histology. We suggest a new concept of predictable developmental biology dealing with 3D histology and histopathology. Our approach is based on two ideas:. These basic ideas allow revealing the principles of spatial organization of epithelial sheets, computing their structural variants and, thereby, predicting and measuring tissue development. Based on these ideas, the computer programs "Histoarch" and "Histored" have been develope...

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Simulation and Reconstruction of 3-D Epithelial Structure.3-D Structural Histology. | gensav.tripod.com Reviews
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Simulation and Reconstruction of 3-D Epithelial Structure. 3-D Structural Histology. We suggest a new concept of predictable developmental biology dealing with 3D histology and histopathology. Our approach is based on two ideas:. These basic ideas allow revealing the principles of spatial organization of epithelial sheets, computing their structural variants and, thereby, predicting and measuring tissue development. Based on these ideas, the computer programs Histoarch and Histored have been develope...
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Simulation and Reconstruction of 3-D Epithelial Structure.3-D Structural Histology. | gensav.tripod.com Reviews

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Simulation and Reconstruction of 3-D Epithelial Structure. 3-D Structural Histology. We suggest a new concept of predictable developmental biology dealing with 3D histology and histopathology. Our approach is based on two ideas:. These basic ideas allow revealing the principles of spatial organization of epithelial sheets, computing their structural variants and, thereby, predicting and measuring tissue development. Based on these ideas, the computer programs "Histoarch" and "Histored" have been develope...

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Bibliography

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1 Savostyanov G.A. The base of structural histology. Spatial organization of epithelia. Sankt Petersburg, Nauka, 2005, 375 p. (Read in Russian). Savost'yanov G. A. Theoretical and Evolutionary Biology: Structural Defects in Regular Cell Mosaics and Their Putative Functional Significance / Paleontological Journal, 2014, Vol. 48, No. 11, pp. 1152-1162. DOI: 10.1134/S0031030114110100. Read this article in Russian. Also read this article in English. 3 Savost`yanov G.A. Modeling of processes of specia...4 Sav...

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An area of the scientific interests

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We are and area of our scientific interests. Authors of this Web-site are working at the Sechenov Institute for Evolutionary Physiology and Biochemistry under the Russian Academy of Science (IEPhB RAS), 44, M. Thorez, St-Petersburg, 194223, Russia. We are a small but energetic team including three experts, as follows from left to right:. Ekatherina Magnitskaya (Savostyanova), PHD, Junior Researcher, Laboratory of Mathematical Simulation of Evolution (now unemployed). The subject of the investigation:.

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Моделирование и реконструкция трехмерной структуры эпителиев.Структурная гистология

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Моделирование и реконструкция трехмерной структуры эпителиев. Структурная гистология. Предлагается новый подход к построению предсказательной биологии развития, а также трехмерной гистологии и патологии. Этот подход базируется на двух идеях:. Эти идеи позволяют выяснять принципы пространственной организации клеточных пластов, вычислять варианты их строения и, тем самым, прогнозировать и измерять тканевое развитие. Полученные модели и их сечения позволили разработать новый подход к реконструкции трехмерно...

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Picture gallery

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2-dimensional (2-d) tissue structure:. 1 Eleven versions of simple epithelia structure. 2 Demonstration of the epithelia stoichiometry. 3 Epithelia chromatic models. 3-dimensional (3-d) tissue structure:. 4 The structure of the frog embryo epidermis consisting of AB cells. 5 The structure of the epedermis consisting of tetragonal cells. 6 Spatial organization of the AB2 two layer sensory epithelium. 7 Spatial organization of the AB2 two layer sensory epithelium (continuation). Back to the Homepage.

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Reconstructing Architecture of 3-D Epithelia

http://gensav.tripod.com/theory.htm

A new approach to reconstruction of epithelia 3-D architectures. The spatial organization of epithelia (pseudostratified or stratified) actually remains unknown so far because of the methodical complexity of the 3-D cell sheets architectonics reconstruction as well as the lack of a sufficiently developed formalized theory of the biologic tissue structure (Lewis 1946, Smolyaninov 1980, Dormer. Maresin 1990 et al. Summary of the Suggested Theory. The advantage of the new approach. Some results and examples.

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Simulation and Reconstruction of 3-D Epithelial Structure.3-D Structural Histology.

Simulation and Reconstruction of 3-D Epithelial Structure. 3-D Structural Histology. We suggest a new concept of predictable developmental biology dealing with 3D histology and histopathology. Our approach is based on two ideas:. These basic ideas allow revealing the principles of spatial organization of epithelial sheets, computing their structural variants and, thereby, predicting and measuring tissue development. Based on these ideas, the computer programs "Histoarch" and "Histored" have been develope...

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